NOP58_USTMA
ID NOP58_USTMA Reviewed; 582 AA.
AC Q4PBF2; A0A0D1CRI5;
DT 23-SEP-2008, integrated into UniProtKB/Swiss-Prot.
DT 19-JUL-2005, sequence version 1.
DT 25-MAY-2022, entry version 84.
DE RecName: Full=Nucleolar protein 58;
GN Name=NOP58; ORFNames=UMAG_02561;
OS Ustilago maydis (strain 521 / FGSC 9021) (Corn smut fungus).
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Ustilaginomycotina;
OC Ustilaginomycetes; Ustilaginales; Ustilaginaceae; Ustilago.
OX NCBI_TaxID=237631;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=521 / FGSC 9021;
RX PubMed=17080091; DOI=10.1038/nature05248;
RA Kaemper J., Kahmann R., Boelker M., Ma L.-J., Brefort T., Saville B.J.,
RA Banuett F., Kronstad J.W., Gold S.E., Mueller O., Perlin M.H.,
RA Woesten H.A.B., de Vries R., Ruiz-Herrera J., Reynaga-Pena C.G.,
RA Snetselaar K., McCann M., Perez-Martin J., Feldbruegge M., Basse C.W.,
RA Steinberg G., Ibeas J.I., Holloman W., Guzman P., Farman M.L.,
RA Stajich J.E., Sentandreu R., Gonzalez-Prieto J.M., Kennell J.C., Molina L.,
RA Schirawski J., Mendoza-Mendoza A., Greilinger D., Muench K., Roessel N.,
RA Scherer M., Vranes M., Ladendorf O., Vincon V., Fuchs U., Sandrock B.,
RA Meng S., Ho E.C.H., Cahill M.J., Boyce K.J., Klose J., Klosterman S.J.,
RA Deelstra H.J., Ortiz-Castellanos L., Li W., Sanchez-Alonso P.,
RA Schreier P.H., Haeuser-Hahn I., Vaupel M., Koopmann E., Friedrich G.,
RA Voss H., Schlueter T., Margolis J., Platt D., Swimmer C., Gnirke A.,
RA Chen F., Vysotskaia V., Mannhaupt G., Gueldener U., Muensterkoetter M.,
RA Haase D., Oesterheld M., Mewes H.-W., Mauceli E.W., DeCaprio D., Wade C.M.,
RA Butler J., Young S.K., Jaffe D.B., Calvo S.E., Nusbaum C., Galagan J.E.,
RA Birren B.W.;
RT "Insights from the genome of the biotrophic fungal plant pathogen Ustilago
RT maydis.";
RL Nature 444:97-101(2006).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=521 / FGSC 9021;
RA Gueldener U., Muensterkoetter M., Walter M.C., Mannhaupt G., Kahmann R.;
RL Submitted (SEP-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Required for pre-18S rRNA processing. May bind microtubules
CC (By similarity). {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Nucleus, nucleolus {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the NOP5/NOP56 family. {ECO:0000305}.
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DR EMBL; CM003145; KIS69213.1; -; Genomic_DNA.
DR RefSeq; XP_011388968.1; XM_011390666.1.
DR AlphaFoldDB; Q4PBF2; -.
DR SMR; Q4PBF2; -.
DR STRING; 5270.UM02561P0; -.
DR EnsemblFungi; KIS69213; KIS69213; UMAG_02561.
DR GeneID; 23563279; -.
DR KEGG; uma:UMAG_02561; -.
DR VEuPathDB; FungiDB:UMAG_02561; -.
DR eggNOG; KOG2572; Eukaryota.
DR HOGENOM; CLU_015495_5_2_1; -.
DR InParanoid; Q4PBF2; -.
DR OMA; TATQELM; -.
DR OrthoDB; 632707at2759; -.
DR Proteomes; UP000000561; Chromosome 6.
DR GO; GO:0031428; C:box C/D RNP complex; IBA:GO_Central.
DR GO; GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
DR GO; GO:0032040; C:small-subunit processome; IBA:GO_Central.
DR GO; GO:0030515; F:snoRNA binding; IBA:GO_Central.
DR GO; GO:0017069; F:snRNA binding; IEA:EnsemblFungi.
DR GO; GO:0000494; P:box C/D RNA 3'-end processing; IEA:EnsemblFungi.
DR GO; GO:0000480; P:endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); IEA:EnsemblFungi.
DR GO; GO:0000447; P:endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); IEA:EnsemblFungi.
DR GO; GO:0000472; P:endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA); IEA:EnsemblFungi.
DR GO; GO:1902570; P:protein localization to nucleolus; IEA:EnsemblFungi.
DR GO; GO:0000452; P:snoRNA guided rRNA 2'-O-methylation; IEA:EnsemblFungi.
DR Gene3D; 1.10.246.90; -; 1.
DR InterPro; IPR045056; Nop56/Nop58.
DR InterPro; IPR012974; NOP5_N.
DR InterPro; IPR042239; Nop_C.
DR InterPro; IPR002687; Nop_dom.
DR InterPro; IPR036070; Nop_dom_sf.
DR InterPro; IPR012976; NOSIC.
DR PANTHER; PTHR10894; PTHR10894; 1.
DR Pfam; PF01798; Nop; 1.
DR Pfam; PF08156; NOP5NT; 1.
DR SMART; SM00931; NOSIC; 1.
DR SUPFAM; SSF89124; SSF89124; 1.
DR PROSITE; PS51358; NOP; 1.
PE 3: Inferred from homology;
KW Nucleus; Reference proteome; Ribonucleoprotein; Ribosome biogenesis;
KW rRNA processing.
FT CHAIN 1..582
FT /note="Nucleolar protein 58"
FT /id="PRO_0000350993"
FT DOMAIN 293..417
FT /note="Nop"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00690"
FT REGION 461..582
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 482..506
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 521..563
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 582 AA; 63155 MW; 664A4665F9B57C76 CRC64;
MVKVLFETAV GFCLFNVSDS SKLEATKNLH ESLDSAEGAS NLLKLSAIHR FTNTAEAVED
ISAINEGKMS KSLKKFLTDE IVEGKGKEKE NLIVAESKLA SNIAKKLGIQ VTYDSELLDL
YRGIRENLAT LLSSSSGDES LDPRDLNTMS LGLSHSLSRY KLKFSPDKVD TMVVQAIGLL
DDLDKEINIY AMRVKEWYGW HFPEMGKIIT DNLAYAKVIR AMGFRTNASA TDFSEILPEE
IEETLKAAAE ISMGTEISET DLEHIWSLCD QVISITQYRT QLYQYLQNRM AAIAPNLTAL
VGDLVGARLI SHAGSLMNLA KHPASTVQIL GAEKALFRAL KTKHDTPKYG LIYHSSLVGQ
APQKLKGKMA RMVATKAALS IRLDALADAD TKSDEGAPTV GIEARAKLES RLRALEMQSG
LSGMRSARNA AGDQGHKQKG FQMEAGGRSY NAAADAAGPS DMASAANMAP SMLPSTPAKP
STTTDEEKKL SKEERKALKK ARKSEIAASE PATPAAASEA GDDKLSKEER KALKKAKKDA
NGVETPKKEK KDKKKRSADE ADVNGTPKSE PGSSKKKKSK KD
