ID   NOP58_VANPO             Reviewed;         514 AA.
AC   A7TIF5;
DT   23-SEP-2008, integrated into UniProtKB/Swiss-Prot.
DT   02-OCT-2007, sequence version 1.
DT   25-MAY-2022, entry version 64.
DE   RecName: Full=Nucleolar protein 58;
GN   Name=NOP58; ORFNames=Kpol_1010p5;
OS   Vanderwaltozyma polyspora (strain ATCC 22028 / DSM 70294 / BCRC 21397 / CBS
OS   2163 / NBRC 10782 / NRRL Y-8283 / UCD 57-17) (Kluyveromyces polysporus).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Vanderwaltozyma.
OX   NCBI_TaxID=436907;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 22028 / DSM 70294 / BCRC 21397 / CBS 2163 / NBRC 10782 / NRRL
RC   Y-8283 / UCD 57-17;
RX   PubMed=17494770; DOI=10.1073/pnas.0608218104;
RA   Scannell D.R., Frank A.C., Conant G.C., Byrne K.P., Woolfit M., Wolfe K.H.;
RT   "Independent sorting-out of thousands of duplicated gene pairs in two yeast
RT   species descended from a whole-genome duplication.";
RL   Proc. Natl. Acad. Sci. U.S.A. 104:8397-8402(2007).
CC   -!- FUNCTION: Required for pre-18S rRNA processing. May bind microtubules
CC       (By similarity). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus, nucleolus {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the NOP5/NOP56 family. {ECO:0000305}.
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DR   EMBL; DS480396; EDO17893.1; -; Genomic_DNA.
DR   RefSeq; XP_001645751.1; XM_001645701.1.
DR   AlphaFoldDB; A7TIF5; -.
DR   SMR; A7TIF5; -.
DR   STRING; 436907.A7TIF5; -.
DR   EnsemblFungi; EDO17893; EDO17893; Kpol_1010p5.
DR   GeneID; 5546142; -.
DR   KEGG; vpo:Kpol_1010p5; -.
DR   eggNOG; KOG2572; Eukaryota.
DR   HOGENOM; CLU_015495_5_2_1; -.
DR   InParanoid; A7TIF5; -.
DR   OMA; MGMRSNW; -.
DR   OrthoDB; 632707at2759; -.
DR   PhylomeDB; A7TIF5; -.
DR   Proteomes; UP000000267; Unassembled WGS sequence.
DR   GO; GO:0031428; C:box C/D RNP complex; IEA:InterPro.
DR   GO; GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
DR   GO; GO:0032040; C:small-subunit processome; IEA:InterPro.
DR   GO; GO:0030515; F:snoRNA binding; IEA:InterPro.
DR   GO; GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.
DR   Gene3D; 1.10.246.90; -; 1.
DR   InterPro; IPR045056; Nop56/Nop58.
DR   InterPro; IPR012974; NOP5_N.
DR   InterPro; IPR042239; Nop_C.
DR   InterPro; IPR002687; Nop_dom.
DR   InterPro; IPR036070; Nop_dom_sf.
DR   InterPro; IPR012976; NOSIC.
DR   PANTHER; PTHR10894; PTHR10894; 1.
DR   Pfam; PF01798; Nop; 1.
DR   Pfam; PF08156; NOP5NT; 1.
DR   SMART; SM00931; NOSIC; 1.
DR   SUPFAM; SSF89124; SSF89124; 1.
DR   PROSITE; PS51358; NOP; 1.
PE   3: Inferred from homology;
KW   Nucleus; Reference proteome; Ribonucleoprotein; Ribosome biogenesis;
KW   rRNA processing.
FT   CHAIN           1..514
FT                   /note="Nucleolar protein 58"
FT                   /id="PRO_0000350994"
FT   DOMAIN          283..403
FT                   /note="Nop"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00690"
FT   REGION          430..514
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        450..494
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        495..514
FT                   /note="Basic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   514 AA;  57190 MW;  EA74207C757527A6 CRC64;
     MAYVLTETSA GYALLKASDK KIYKSSSLIQ DLDSSDKVLK EFKIAAFSKF NSAANALEEA
     NSIIEGKVSP QLQKLLEEAK KDKKSTLVVS ETKLANAINK LGLNFNVVSD AVTLDIYRAV
     KEYLPDLLPG LNDTDLSKMS LGLAHSIGRH KLKFSADKVD VMIIQAIALL DDLDKELNTY
     AMRCKEWYGW HFPELAKIVT DSVAYARIIL AMGVRSKCAD TDLSEILPEE VEERVKTAAE
     VSMGTEITET DLDNIKALAD QIVDFAAYRE QLSNYLSSRM KAIAPNLTQL VGELVGARLI
     AHSGSLISLA KSPASTIQIL GAEKALFRAL KTKHDTPKYG LLYHASLVGQ ATGKNKGKIA
     RVLAAKAAVS LRYDALAEDR DDSGDIGLEA RAKVENRLSQ LEGRDLRTTP KVVREAKKVE
     ITEARAYNAD ADTAAVEESA SDSDDEEEEE DKKKEKKEKK DKKDKKDKKD KKDKKRKRDE
     EDEEKKESKK SKKDKKEKKE KKDKKDKKSK KEKK