NOP5B_ARATH
ID NOP5B_ARATH Reviewed; 533 AA.
AC Q9MAB3;
DT 15-MAY-2007, integrated into UniProtKB/Swiss-Prot.
DT 01-OCT-2000, sequence version 1.
DT 25-MAY-2022, entry version 124.
DE RecName: Full=Probable nucleolar protein 5-2;
DE AltName: Full=MAR-binding NOP56/58 homolog 2;
DE AltName: Full=Nucleolar protein 58-2;
GN Name=NOP5-2; Synonyms=NOP58-2; OrderedLocusNames=At3g05060;
GN ORFNames=T12H1.2;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA].
RA Phelan T.J., Spiker S.L.;
RT "Arabidopsis MAR binding NOP56/58 homologs.";
RL Submitted (SEP-2000) to the EMBL/GenBank/DDBJ databases.
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130713; DOI=10.1038/35048706;
RA Salanoubat M., Lemcke K., Rieger M., Ansorge W., Unseld M., Fartmann B.,
RA Valle G., Bloecker H., Perez-Alonso M., Obermaier B., Delseny M.,
RA Boutry M., Grivell L.A., Mache R., Puigdomenech P., De Simone V.,
RA Choisne N., Artiguenave F., Robert C., Brottier P., Wincker P.,
RA Cattolico L., Weissenbach J., Saurin W., Quetier F., Schaefer M.,
RA Mueller-Auer S., Gabel C., Fuchs M., Benes V., Wurmbach E., Drzonek H.,
RA Erfle H., Jordan N., Bangert S., Wiedelmann R., Kranz H., Voss H.,
RA Holland R., Brandt P., Nyakatura G., Vezzi A., D'Angelo M., Pallavicini A.,
RA Toppo S., Simionati B., Conrad A., Hornischer K., Kauer G., Loehnert T.-H.,
RA Nordsiek G., Reichelt J., Scharfe M., Schoen O., Bargues M., Terol J.,
RA Climent J., Navarro P., Collado C., Perez-Perez A., Ottenwaelder B.,
RA Duchemin D., Cooke R., Laudie M., Berger-Llauro C., Purnelle B., Masuy D.,
RA de Haan M., Maarse A.C., Alcaraz J.-P., Cottet A., Casacuberta E.,
RA Monfort A., Argiriou A., Flores M., Liguori R., Vitale D., Mannhaupt G.,
RA Haase D., Schoof H., Rudd S., Zaccaria P., Mewes H.-W., Mayer K.F.X.,
RA Kaul S., Town C.D., Koo H.L., Tallon L.J., Jenkins J., Rooney T., Rizzo M.,
RA Walts A., Utterback T., Fujii C.Y., Shea T.P., Creasy T.H., Haas B.,
RA Maiti R., Wu D., Peterson J., Van Aken S., Pai G., Militscher J.,
RA Sellers P., Gill J.E., Feldblyum T.V., Preuss D., Lin X., Nierman W.C.,
RA Salzberg S.L., White O., Venter J.C., Fraser C.M., Kaneko T., Nakamura Y.,
RA Sato S., Kato T., Asamizu E., Sasamoto S., Kimura T., Idesawa K.,
RA Kawashima K., Kishida Y., Kiyokawa C., Kohara M., Matsumoto M., Matsuno A.,
RA Muraki A., Nakayama S., Nakazaki N., Shinpo S., Takeuchi C., Wada T.,
RA Watanabe A., Yamada M., Yasuda M., Tabata S.;
RT "Sequence and analysis of chromosome 3 of the plant Arabidopsis thaliana.";
RL Nature 408:820-822(2000).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=14593172; DOI=10.1126/science.1088305;
RA Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA Ecker J.R.;
RT "Empirical analysis of transcriptional activity in the Arabidopsis
RT genome.";
RL Science 302:842-846(2003).
RN [5]
RP IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RC STRAIN=cv. Landsberg erecta;
RX PubMed=17272265; DOI=10.1074/mcp.m600408-mcp200;
RA Maor R., Jones A., Nuehse T.S., Studholme D.J., Peck S.C., Shirasu K.;
RT "Multidimensional protein identification technology (MudPIT) analysis of
RT ubiquitinated proteins in plants.";
RL Mol. Cell. Proteomics 6:601-610(2007).
CC -!- FUNCTION: Required for 60S ribosomal subunit biogenesis. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Nucleus, nucleolus {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the NOP5/NOP56 family. {ECO:0000305}.
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DR EMBL; AF302491; AAG40837.1; -; mRNA.
DR EMBL; AC009177; AAF27012.1; -; Genomic_DNA.
DR EMBL; CP002686; AEE74181.1; -; Genomic_DNA.
DR EMBL; AF412080; AAL06533.1; -; mRNA.
DR RefSeq; NP_187157.1; NM_111378.4.
DR AlphaFoldDB; Q9MAB3; -.
DR SMR; Q9MAB3; -.
DR BioGRID; 5003; 43.
DR IntAct; Q9MAB3; 5.
DR STRING; 3702.AT3G05060.1; -.
DR iPTMnet; Q9MAB3; -.
DR MetOSite; Q9MAB3; -.
DR PaxDb; Q9MAB3; -.
DR PRIDE; Q9MAB3; -.
DR ProteomicsDB; 250540; -.
DR EnsemblPlants; AT3G05060.1; AT3G05060.1; AT3G05060.
DR GeneID; 819668; -.
DR Gramene; AT3G05060.1; AT3G05060.1; AT3G05060.
DR KEGG; ath:AT3G05060; -.
DR Araport; AT3G05060; -.
DR TAIR; locus:2096214; AT3G05060.
DR eggNOG; KOG2572; Eukaryota.
DR HOGENOM; CLU_015495_5_2_1; -.
DR InParanoid; Q9MAB3; -.
DR OMA; THCDGET; -.
DR OrthoDB; 632707at2759; -.
DR PhylomeDB; Q9MAB3; -.
DR PRO; PR:Q9MAB3; -.
DR Proteomes; UP000006548; Chromosome 3.
DR ExpressionAtlas; Q9MAB3; baseline and differential.
DR Genevisible; Q9MAB3; AT.
DR GO; GO:0031428; C:box C/D RNP complex; IBA:GO_Central.
DR GO; GO:0005730; C:nucleolus; HDA:TAIR.
DR GO; GO:0032040; C:small-subunit processome; IBA:GO_Central.
DR GO; GO:0003729; F:mRNA binding; IDA:TAIR.
DR GO; GO:0030515; F:snoRNA binding; IBA:GO_Central.
DR GO; GO:0042254; P:ribosome biogenesis; IEA:UniProtKB-KW.
DR Gene3D; 1.10.246.90; -; 1.
DR InterPro; IPR045056; Nop56/Nop58.
DR InterPro; IPR012974; NOP5_N.
DR InterPro; IPR042239; Nop_C.
DR InterPro; IPR002687; Nop_dom.
DR InterPro; IPR036070; Nop_dom_sf.
DR InterPro; IPR012976; NOSIC.
DR PANTHER; PTHR10894; PTHR10894; 1.
DR Pfam; PF01798; Nop; 1.
DR Pfam; PF08156; NOP5NT; 1.
DR SMART; SM00931; NOSIC; 1.
DR SUPFAM; SSF89124; SSF89124; 1.
DR PROSITE; PS51358; NOP; 1.
PE 1: Evidence at protein level;
KW Nucleus; Reference proteome; Ribosome biogenesis.
FT CHAIN 1..533
FT /note="Probable nucleolar protein 5-2"
FT /id="PRO_0000287348"
FT DOMAIN 281..399
FT /note="Nop"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00690"
FT REGION 401..433
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 445..533
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 450..522
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 533 AA; 59003 MW; 26BD22129A52B2CE CRC64;
MVLVLYETAA GFALFKVKDE GKMANVEDLC KEFDTPDSAR KMVKLKAFEK FDNTSEALEA
VAKLLEGAPS KGLRKFLKAN CQGETLAVAD SKLGNVIKEK LKIDCIHNNA VMELLRGVRS
QFTELISGLG DQDLAPMSLG LSHSLARYKL KFSSDKVDTM IIQAIGLLDD LDKELNTYAM
RVREWYGWHF PELAKIISDN ILYAKSVKLM GNRVNAAKLD FSEILADEIE ADLKDAAVIS
MGTEVSDLDL LHIRELCDQV LSLSEYRAQL YDYLKSRMNT IAPNLTALVG ELVGARLISH
GGSLLNLSKQ PGSTVQILGA EKALFRALKT KHATPKYGLI FHASLVGQAA PKHKGKISRS
LAAKTVLAIR VDALGDSQDN TMGLENRAKL EARLRNLEGK DLGRLSGSSK GKPKIEVYNK
DKKMGSGGLI TPAKTYNTAA DSLLGETSAK SEEPSKKKDK KKKKKVEEEK PEEEEPSEKK
KKKKAEAETE AVVEVAKEEK KKNKKKRKHE EEETTETPAK KKDKKEKKKK SKD
