NOP5C_ARATH
ID NOP5C_ARATH Reviewed; 450 AA.
AC O04656; F4K2U4;
DT 01-NOV-1997, integrated into UniProtKB/Swiss-Prot.
DT 15-MAY-2007, sequence version 2.
DT 25-MAY-2022, entry version 129.
DE RecName: Full=Putative nucleolar protein 5-3;
DE AltName: Full=Nucleolar protein 58-3;
GN Name=NOP5-3; Synonyms=NOP58-3; OrderedLocusNames=At5g27140;
GN ORFNames=T21B4_50, TM021B04.13;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130714; DOI=10.1038/35048507;
RA Tabata S., Kaneko T., Nakamura Y., Kotani H., Kato T., Asamizu E.,
RA Miyajima N., Sasamoto S., Kimura T., Hosouchi T., Kawashima K., Kohara M.,
RA Matsumoto M., Matsuno A., Muraki A., Nakayama S., Nakazaki N., Naruo K.,
RA Okumura S., Shinpo S., Takeuchi C., Wada T., Watanabe A., Yamada M.,
RA Yasuda M., Sato S., de la Bastide M., Huang E., Spiegel L., Gnoj L.,
RA O'Shaughnessy A., Preston R., Habermann K., Murray J., Johnson D.,
RA Rohlfing T., Nelson J., Stoneking T., Pepin K., Spieth J., Sekhon M.,
RA Armstrong J., Becker M., Belter E., Cordum H., Cordes M., Courtney L.,
RA Courtney W., Dante M., Du H., Edwards J., Fryman J., Haakensen B.,
RA Lamar E., Latreille P., Leonard S., Meyer R., Mulvaney E., Ozersky P.,
RA Riley A., Strowmatt C., Wagner-McPherson C., Wollam A., Yoakum M., Bell M.,
RA Dedhia N., Parnell L., Shah R., Rodriguez M., Hoon See L., Vil D.,
RA Baker J., Kirchoff K., Toth K., King L., Bahret A., Miller B., Marra M.A.,
RA Martienssen R., McCombie W.R., Wilson R.K., Murphy G., Bancroft I.,
RA Volckaert G., Wambutt R., Duesterhoeft A., Stiekema W., Pohl T.,
RA Entian K.-D., Terryn N., Hartley N., Bent E., Johnson S., Langham S.-A.,
RA McCullagh B., Robben J., Grymonprez B., Zimmermann W., Ramsperger U.,
RA Wedler H., Balke K., Wedler E., Peters S., van Staveren M., Dirkse W.,
RA Mooijman P., Klein Lankhorst R., Weitzenegger T., Bothe G., Rose M.,
RA Hauf J., Berneiser S., Hempel S., Feldpausch M., Lamberth S.,
RA Villarroel R., Gielen J., Ardiles W., Bents O., Lemcke K., Kolesov G.,
RA Mayer K.F.X., Rudd S., Schoof H., Schueller C., Zaccaria P., Mewes H.-W.,
RA Bevan M., Fransz P.F.;
RT "Sequence and analysis of chromosome 5 of the plant Arabidopsis thaliana.";
RL Nature 408:823-826(2000).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
CC -!- FUNCTION: Required for 60S ribosomal subunit biogenesis. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Nucleus, nucleolus {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the NOP5/NOP56 family. {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=AAB61074.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
CC Sequence=AED93654.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR EMBL; AF007271; AAB61074.1; ALT_SEQ; Genomic_DNA.
DR EMBL; CP002688; AED93654.1; ALT_SEQ; Genomic_DNA.
DR EMBL; CP002688; ANM68536.1; -; Genomic_DNA.
DR PIR; T01805; T01805.
DR RefSeq; NP_001330282.1; NM_001343993.1.
DR RefSeq; NP_198066.1; NM_122596.1.
DR AlphaFoldDB; O04656; -.
DR SMR; O04656; -.
DR BioGRID; 18046; 37.
DR STRING; 3702.AT5G27140.1; -.
DR PaxDb; O04656; -.
DR PRIDE; O04656; -.
DR ProteomicsDB; 251070; -.
DR EnsemblPlants; AT5G27140.2; AT5G27140.2; AT5G27140.
DR GeneID; 832772; -.
DR Gramene; AT5G27140.2; AT5G27140.2; AT5G27140.
DR KEGG; ath:AT5G27140; -.
DR Araport; AT5G27140; -.
DR eggNOG; KOG2572; Eukaryota.
DR HOGENOM; CLU_015495_5_2_1; -.
DR InParanoid; O04656; -.
DR OrthoDB; 632707at2759; -.
DR PhylomeDB; O04656; -.
DR PRO; PR:O04656; -.
DR Proteomes; UP000006548; Chromosome 5.
DR ExpressionAtlas; O04656; baseline and differential.
DR Genevisible; O04656; AT.
DR GO; GO:0031428; C:box C/D RNP complex; IBA:GO_Central.
DR GO; GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
DR GO; GO:0032040; C:small-subunit processome; IBA:GO_Central.
DR GO; GO:0030515; F:snoRNA binding; IBA:GO_Central.
DR GO; GO:0042254; P:ribosome biogenesis; IEA:UniProtKB-KW.
DR Gene3D; 1.10.246.90; -; 1.
DR InterPro; IPR045056; Nop56/Nop58.
DR InterPro; IPR012974; NOP5_N.
DR InterPro; IPR042239; Nop_C.
DR InterPro; IPR002687; Nop_dom.
DR InterPro; IPR036070; Nop_dom_sf.
DR InterPro; IPR012976; NOSIC.
DR PANTHER; PTHR10894; PTHR10894; 2.
DR Pfam; PF01798; Nop; 1.
DR Pfam; PF08156; NOP5NT; 1.
DR SMART; SM00931; NOSIC; 1.
DR SUPFAM; SSF89124; SSF89124; 1.
DR PROSITE; PS51358; NOP; 1.
PE 3: Inferred from homology;
KW Nucleus; Reference proteome; Ribosome biogenesis.
FT CHAIN 1..450
FT /note="Putative nucleolar protein 5-3"
FT /id="PRO_0000219032"
FT DOMAIN 252..370
FT /note="Nop"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00690"
FT REGION 375..423
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 381..423
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 450 AA; 49935 MW; 388773BE16346912 CRC64;
MLVLFETSGG FALFKVLDEG KLSNVEDLGT EFYSAESARR MGLHKFLKNN CDDGEILAVA
DPKLGDIITE KLDIECVHND AVMELLRGVR SQLTELLSGL DDNDLAPVSL ELSHILARYK
LKITSDKVET MIILSISLLD DLDKELNTYT TSVCELYGLH FPELANIVQD NILYAKVVKL
MGNRINAATL DFSEILADEV EAELKEASMV STRTEVSDLD LMHIQELCDQ VLSIAEDKTL
LCDDLKNKMN KIAPNLTALV GELVGARLIS HCGSLWNLSK LPWSTIQILG AEKTLYKALK
TKQATPKYGL IYHAPLVRQA APENKGKIAR SLAAKSALAI RCDAFGNGQD NTMGVESRLK
LEARLRNLEG GDLGACEEEE EVNDKDTKKE ADDEEEPKTE ECSKKRKKEA ELETVEDPAK
KSKQEGVTGL LLLMLLISLI YFFSVNQLLW
