NOP9_ASPFU
ID NOP9_ASPFU Reviewed; 699 AA.
AC Q4WXY3;
DT 03-MAY-2011, integrated into UniProtKB/Swiss-Prot.
DT 05-JUL-2005, sequence version 1.
DT 25-MAY-2022, entry version 91.
DE RecName: Full=Nucleolar protein 9;
DE AltName: Full=Pumilio domain-containing protein nop9;
GN Name=nop9; ORFNames=AFUA_3G11110;
OS Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC
OS A1100) (Aspergillus fumigatus).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus;
OC Aspergillus subgen. Fumigati.
OX NCBI_TaxID=330879;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100;
RX PubMed=16372009; DOI=10.1038/nature04332;
RA Nierman W.C., Pain A., Anderson M.J., Wortman J.R., Kim H.S., Arroyo J.,
RA Berriman M., Abe K., Archer D.B., Bermejo C., Bennett J.W., Bowyer P.,
RA Chen D., Collins M., Coulsen R., Davies R., Dyer P.S., Farman M.L.,
RA Fedorova N., Fedorova N.D., Feldblyum T.V., Fischer R., Fosker N.,
RA Fraser A., Garcia J.L., Garcia M.J., Goble A., Goldman G.H., Gomi K.,
RA Griffith-Jones S., Gwilliam R., Haas B.J., Haas H., Harris D.E.,
RA Horiuchi H., Huang J., Humphray S., Jimenez J., Keller N., Khouri H.,
RA Kitamoto K., Kobayashi T., Konzack S., Kulkarni R., Kumagai T., Lafton A.,
RA Latge J.-P., Li W., Lord A., Lu C., Majoros W.H., May G.S., Miller B.L.,
RA Mohamoud Y., Molina M., Monod M., Mouyna I., Mulligan S., Murphy L.D.,
RA O'Neil S., Paulsen I., Penalva M.A., Pertea M., Price C., Pritchard B.L.,
RA Quail M.A., Rabbinowitsch E., Rawlins N., Rajandream M.A., Reichard U.,
RA Renauld H., Robson G.D., Rodriguez de Cordoba S., Rodriguez-Pena J.M.,
RA Ronning C.M., Rutter S., Salzberg S.L., Sanchez M., Sanchez-Ferrero J.C.,
RA Saunders D., Seeger K., Squares R., Squares S., Takeuchi M., Tekaia F.,
RA Turner G., Vazquez de Aldana C.R., Weidman J., White O., Woodward J.R.,
RA Yu J.-H., Fraser C.M., Galagan J.E., Asai K., Machida M., Hall N.,
RA Barrell B.G., Denning D.W.;
RT "Genomic sequence of the pathogenic and allergenic filamentous fungus
RT Aspergillus fumigatus.";
RL Nature 438:1151-1156(2005).
CC -!- FUNCTION: RNA-binding nucleolar protein required for pre-rRNA
CC processing. Involved in production of 18S rRNA and assembly of small
CC ribosomal subunit (By similarity). {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Nucleus, nucleolus {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the NOP9 family. {ECO:0000305}.
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DR EMBL; AAHF01000002; EAL92470.1; -; Genomic_DNA.
DR RefSeq; XP_754508.1; XM_749415.1.
DR AlphaFoldDB; Q4WXY3; -.
DR SMR; Q4WXY3; -.
DR STRING; 746128.CADAFUBP00003725; -.
DR EnsemblFungi; EAL92470; EAL92470; AFUA_3G11110.
DR GeneID; 3512084; -.
DR KEGG; afm:AFUA_3G11110; -.
DR VEuPathDB; FungiDB:Afu3g11110; -.
DR eggNOG; KOG2188; Eukaryota.
DR HOGENOM; CLU_008720_1_1_1; -.
DR InParanoid; Q4WXY3; -.
DR OMA; TPNGSHI; -.
DR OrthoDB; 238378at2759; -.
DR Proteomes; UP000002530; Chromosome 3.
DR GO; GO:0030686; C:90S preribosome; IBA:GO_Central.
DR GO; GO:0005730; C:nucleolus; IBA:GO_Central.
DR GO; GO:0030688; C:preribosome, small subunit precursor; IBA:GO_Central.
DR GO; GO:0003723; F:RNA binding; IBA:GO_Central.
DR GO; GO:0000480; P:endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); IBA:GO_Central.
DR GO; GO:0000447; P:endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); IBA:GO_Central.
DR GO; GO:0000472; P:endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA); IBA:GO_Central.
DR GO; GO:0000056; P:ribosomal small subunit export from nucleus; IBA:GO_Central.
DR Gene3D; 1.25.10.10; -; 2.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR040000; NOP9.
DR InterPro; IPR001313; Pumilio_RNA-bd_rpt.
DR PANTHER; PTHR13102; PTHR13102; 1.
DR Pfam; PF00806; PUF; 2.
DR SMART; SM00025; Pumilio; 5.
DR SUPFAM; SSF48371; SSF48371; 1.
PE 3: Inferred from homology;
KW Nucleus; Reference proteome; Repeat; Ribosome biogenesis; rRNA processing.
FT CHAIN 1..699
FT /note="Nucleolar protein 9"
FT /id="PRO_0000407799"
FT REPEAT 120..155
FT /note="Pumilio 1"
FT REPEAT 156..191
FT /note="Pumilio 2"
FT REPEAT 361..396
FT /note="Pumilio 3"
FT REPEAT 397..433
FT /note="Pumilio 4"
FT REPEAT 540..580
FT /note="Pumilio 5"
FT REPEAT 582..619
FT /note="Pumilio 6"
FT REGION 1..66
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 491..510
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..37
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 38..52
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 491..505
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 699 AA; 78077 MW; 243324A9DAA0B5EB CRC64;
MPREKQKRGR RAEDKAKKDA AKRKRDEGPE ESAVKRLKPS AETNTSNNEI ISGADYIPLG
QDDGGNDVPM NDAPANDMPF YGLLDSEEQE YFSKANEVLE LNQFHDAEER RLFVDSVYRE
ADGKELKVAC SQSCSRLMEK LISLSDMRQI RRLFSKFIGH FLHLVQHRFA SHCCETLFIN
AAPGVTEKIS KSKGRKAEVD EEDEPEPELS LAEMFMKVVE ELEGNWGYLL TERFASHTIR
VLLFVLAGEP VDLSSTDSVV ASRKKERLGI VNTEAPEEKA AAEKRKVPEV FEATLKKVMN
DMVSGLDNTY LRALATHPVG NPVLQVLVFL ELSHFGKASA KDPNSIIRRL IPDDDFGENA
ESSTFVRGLL YDPVGSRLLE TIIKSMPGKL FKSLYKNIIR DRIGSLARNT TAGYVVLRTL
ERLGKDDLQD AMESIIPEIP GLIERSRLIV PKVLIERCLV RGVDTKPLSD ALESAYDKDP
AQRLEQMLKL EPAASEDDSE EKRKQTGNNQ TAAAEKLHGS LLAQTMLTAS GPVSGLIYSS
LLAQSPDSLL RLAKDPTASR VLQQALTAPT STSQFRRQFT TRFSGHLVEL ALDSSGSHVV
DALWPATKDL FFVKERMAQE LLNEELSLRD SFVGRAVWRN WSMDLYKRRR GEWASKAKGL
DSIENGQRER PKSRIDLARA KFAAKAAEES SKAPVAAKT
