ID   NOP9_ASPNC              Reviewed;         692 AA.
AC   A2R3A7;
DT   03-MAY-2011, integrated into UniProtKB/Swiss-Prot.
DT   06-MAR-2007, sequence version 1.
DT   25-MAY-2022, entry version 66.
DE   RecName: Full=Nucleolar protein 9;
DE   AltName: Full=Pumilio domain-containing protein nop9;
GN   Name=nop9; ORFNames=An14g03620;
OS   Aspergillus niger (strain CBS 513.88 / FGSC A1513).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus;
OC   Aspergillus subgen. Circumdati.
OX   NCBI_TaxID=425011;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CBS 513.88 / FGSC A1513 / ATCC MYA-4892;
RX   PubMed=17259976; DOI=10.1038/nbt1282;
RA   Pel H.J., de Winde J.H., Archer D.B., Dyer P.S., Hofmann G., Schaap P.J.,
RA   Turner G., de Vries R.P., Albang R., Albermann K., Andersen M.R.,
RA   Bendtsen J.D., Benen J.A.E., van den Berg M., Breestraat S., Caddick M.X.,
RA   Contreras R., Cornell M., Coutinho P.M., Danchin E.G.J., Debets A.J.M.,
RA   Dekker P., van Dijck P.W.M., van Dijk A., Dijkhuizen L., Driessen A.J.M.,
RA   d'Enfert C., Geysens S., Goosen C., Groot G.S.P., de Groot P.W.J.,
RA   Guillemette T., Henrissat B., Herweijer M., van den Hombergh J.P.T.W.,
RA   van den Hondel C.A.M.J.J., van der Heijden R.T.J.M., van der Kaaij R.M.,
RA   Klis F.M., Kools H.J., Kubicek C.P., van Kuyk P.A., Lauber J., Lu X.,
RA   van der Maarel M.J.E.C., Meulenberg R., Menke H., Mortimer M.A.,
RA   Nielsen J., Oliver S.G., Olsthoorn M., Pal K., van Peij N.N.M.E.,
RA   Ram A.F.J., Rinas U., Roubos J.A., Sagt C.M.J., Schmoll M., Sun J.,
RA   Ussery D., Varga J., Vervecken W., van de Vondervoort P.J.J., Wedler H.,
RA   Woesten H.A.B., Zeng A.-P., van Ooyen A.J.J., Visser J., Stam H.;
RT   "Genome sequencing and analysis of the versatile cell factory Aspergillus
RT   niger CBS 513.88.";
RL   Nat. Biotechnol. 25:221-231(2007).
CC   -!- FUNCTION: RNA-binding nucleolar protein required for pre-rRNA
CC       processing. Involved in production of 18S rRNA and assembly of small
CC       ribosomal subunit (By similarity). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus, nucleolus {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the NOP9 family. {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AM270320; CAK46599.1; -; Genomic_DNA.
DR   AlphaFoldDB; A2R3A7; -.
DR   SMR; A2R3A7; -.
DR   PaxDb; A2R3A7; -.
DR   EnsemblFungi; CAK46599; CAK46599; An14g03620.
DR   VEuPathDB; FungiDB:An14g03620; -.
DR   HOGENOM; CLU_008720_1_1_1; -.
DR   Proteomes; UP000006706; Chromosome 1R.
DR   GO; GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR   GO; GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.
DR   Gene3D; 1.25.10.10; -; 3.
DR   InterPro; IPR011989; ARM-like.
DR   InterPro; IPR016024; ARM-type_fold.
DR   InterPro; IPR040000; NOP9.
DR   InterPro; IPR001313; Pumilio_RNA-bd_rpt.
DR   PANTHER; PTHR13102; PTHR13102; 1.
DR   Pfam; PF00806; PUF; 1.
DR   SMART; SM00025; Pumilio; 7.
DR   SUPFAM; SSF48371; SSF48371; 1.
PE   3: Inferred from homology;
KW   Nucleus; Reference proteome; Repeat; Ribosome biogenesis; rRNA processing.
FT   CHAIN           1..692
FT                   /note="Nucleolar protein 9"
FT                   /id="PRO_0000407800"
FT   REPEAT          96..131
FT                   /note="Pumilio 1"
FT   REPEAT          132..168
FT                   /note="Pumilio 2"
FT   REPEAT          196..231
FT                   /note="Pumilio 3"
FT   REPEAT          335..370
FT                   /note="Pumilio 4"
FT   REPEAT          371..407
FT                   /note="Pumilio 5"
FT   REPEAT          535..575
FT                   /note="Pumilio 6"
FT   REPEAT          577..614
FT                   /note="Pumilio 7"
FT   REGION          1..53
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          163..182
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          466..507
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1..43
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        466..485
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   692 AA;  77763 MW;  07104C135453D271 CRC64;
     MPREKVKRGR RATEKANKEA SKRKRDDAPE DVVPKRVKPS DDETNDFGAQ TGDMPFYGLL
     DPEEQEYFSR ANEVLETNQF GDAEERRVFV ESVYKEAEGK ELKISCSQSC SRLMEKLISM
     SDIHQIRRLF SKFIGHFLHL VQHRFASHCC ETLFIHAAPG VSQKPSKKAS KTEAEEGDEP
     EPELSLAEMF MKVIEELEGN WGYLLTERFA SHTIRVLLLV LAGEPVDLSL SDSVVASRKK
     ERHGVLNEVQ DENPVAQKRS VPESFEGTLK KIMQDMVSVL DDTYLRALAT HPVGNPVLQV
     LVYLELSHFG KASAKDPKSI IRRLIPDDTF EEGTESTVFI RGLLYDPVGS RLLETIVRYM
     PGKLFKGLYK NFLRDQLRSL SRNITAGYVV LKVLERLGKD DLENAVELLV PQIPNLIERS
     RVIVPKTLVE RCIVRGVDTT PIARSLETAY DSDPAKRLSQ MLTLEDTTTT SEPQQQNQAQ
     DQDDHQQPPA IPDFGPDNAN ANINTNPKGA KLHNSLFVQT ILTAPGPLSA LVYSSLLSQT
     PESLLTIAKD PTASHVIQKS LTLPTSTPQF RRQFAVRFTG HLEELALDSS GSRVVDALWH
     ATKDVFFVKE RMAQELARSE MALRDSFVGR AVWRNWSMDL YKRRRGEWAA KAKGLDVGGE
     GGQKPKSRIE LARERFAAKA AESEKKKNGE DA