NOP9_BLAGS
ID NOP9_BLAGS Reviewed; 682 AA.
AC C5JK19; A0A179UFF3;
DT 03-MAY-2011, integrated into UniProtKB/Swiss-Prot.
DT 28-JUL-2009, sequence version 1.
DT 03-AUG-2022, entry version 51.
DE RecName: Full=Nucleolar protein 9;
DE AltName: Full=Pumilio domain-containing protein NOP9;
GN Name=NOP9; ORFNames=BDBG_02872;
OS Blastomyces gilchristii (strain SLH14081) (Blastomyces dermatitidis).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Onygenales; Ajellomycetaceae; Blastomyces.
OX NCBI_TaxID=559298;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SLH14081;
RX PubMed=26439490; DOI=10.1371/journal.pgen.1005493;
RA Munoz J.F., Gauthier G.M., Desjardins C.A., Gallo J.E., Holder J.,
RA Sullivan T.D., Marty A.J., Carmen J.C., Chen Z., Ding L., Gujja S.,
RA Magrini V., Misas E., Mitreva M., Priest M., Saif S., Whiston E.A.,
RA Young S., Zeng Q., Goldman W.E., Mardis E.R., Taylor J.W., McEwen J.G.,
RA Clay O.K., Klein B.S., Cuomo C.A.;
RT "The dynamic genome and transcriptome of the human fungal pathogen
RT Blastomyces and close relative Emmonsia.";
RL PLoS Genet. 11:E1005493-E1005493(2015).
CC -!- FUNCTION: RNA-binding nucleolar protein required for pre-rRNA
CC processing. Involved in production of 18S rRNA and assembly of small
CC ribosomal subunit (By similarity). {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Nucleus, nucleolus {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the NOP9 family. {ECO:0000305}.
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DR EMBL; GG657451; OAT06704.1; -; Genomic_DNA.
DR RefSeq; XP_002626695.1; XM_002626649.1.
DR AlphaFoldDB; C5JK19; -.
DR SMR; C5JK19; -.
DR STRING; 559298.C5JK19; -.
DR PRIDE; C5JK19; -.
DR EnsemblFungi; OAT06704; OAT06704; BDBG_02872.
DR GeneID; 8510002; -.
DR KEGG; bgh:BDBG_02872; -.
DR VEuPathDB; FungiDB:BDBG_02872; -.
DR HOGENOM; CLU_008720_1_1_1; -.
DR Proteomes; UP000002038; Unassembled WGS sequence.
DR GO; GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
DR GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR GO; GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.
DR Gene3D; 1.25.10.10; -; 3.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR040000; NOP9.
DR InterPro; IPR001313; Pumilio_RNA-bd_rpt.
DR PANTHER; PTHR13102; PTHR13102; 1.
DR SMART; SM00025; Pumilio; 5.
DR SUPFAM; SSF48371; SSF48371; 1.
PE 3: Inferred from homology;
KW Nucleus; Reference proteome; Repeat; Ribosome biogenesis; rRNA processing.
FT CHAIN 1..682
FT /note="Nucleolar protein 9"
FT /id="PRO_0000407792"
FT REPEAT 108..143
FT /note="Pumilio 1"
FT REPEAT 347..382
FT /note="Pumilio 2"
FT REPEAT 383..419
FT /note="Pumilio 3"
FT REPEAT 524..562
FT /note="Pumilio 4"
FT REPEAT 563..600
FT /note="Pumilio 5"
FT REGION 1..46
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 249..272
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..37
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 249..270
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 682 AA; 76477 MW; 179FED85FD8DCDB6 CRC64;
MPRERQKRGR RAEAKRKRDD EVGDRTAPKR QKASEGDNDF NPLHSQAKIG DDYIPLEEEP
ASSMDTPFYG LLDPDEQEYF SHASGLLELN QFETEEEKSI FIERVYEEAD GKELKIACSQ
SCSRLMEKLI SASTVSQIKS LFNKFVGQFL NLVQHRFASH CCESLFLRAA PYVTLEMKKN
SAEKNDNECE DSSANLRLED LFLAVLSELE GNWGYLLTER FASHTIRVLL LILAGEQLDN
PSKATVIASR KKENLDKPKV TQRDKSASDR RAVPPSFNAA LEKMMNDLVT GLDNTYLRAL
ATHPVGNPVL QVLLSVELTH LGKSKARDPD SVFRRLVPDE NLEEGSESAA FIKGLFYDPV
GSRLLETMVQ LAPGKFFKTF YKALVLERIG SLSRNEIAGH VVARILERLS KEDLKSSMDL
ILPEVLSLVK RSRFTVIKTL IERGVIRGVD LRPLADSLLL AFGTDPIARI NNVLKLHHLN
EENDDTKRSS KNSTPEQLHG SLLAQTMLKA PGPLSELIQS SLLAVTLETL IAIAKDPVAS
HVLQDALTLP TSTIQFRRQI TSRFSGKMAE LALDSSGSHV VDAVWSATEN LIFIKQRFAE
ELLANERPLR DSFVGRAVWK NWSMDLYKRR RGHWIAVAKG LESVNPSNSE NRQPPKSNLD
LARARFAEKS NTSTPKKISA TF