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NOP9_BLAGS
ID   NOP9_BLAGS              Reviewed;         682 AA.
AC   C5JK19; A0A179UFF3;
DT   03-MAY-2011, integrated into UniProtKB/Swiss-Prot.
DT   28-JUL-2009, sequence version 1.
DT   03-AUG-2022, entry version 51.
DE   RecName: Full=Nucleolar protein 9;
DE   AltName: Full=Pumilio domain-containing protein NOP9;
GN   Name=NOP9; ORFNames=BDBG_02872;
OS   Blastomyces gilchristii (strain SLH14081) (Blastomyces dermatitidis).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Onygenales; Ajellomycetaceae; Blastomyces.
OX   NCBI_TaxID=559298;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=SLH14081;
RX   PubMed=26439490; DOI=10.1371/journal.pgen.1005493;
RA   Munoz J.F., Gauthier G.M., Desjardins C.A., Gallo J.E., Holder J.,
RA   Sullivan T.D., Marty A.J., Carmen J.C., Chen Z., Ding L., Gujja S.,
RA   Magrini V., Misas E., Mitreva M., Priest M., Saif S., Whiston E.A.,
RA   Young S., Zeng Q., Goldman W.E., Mardis E.R., Taylor J.W., McEwen J.G.,
RA   Clay O.K., Klein B.S., Cuomo C.A.;
RT   "The dynamic genome and transcriptome of the human fungal pathogen
RT   Blastomyces and close relative Emmonsia.";
RL   PLoS Genet. 11:E1005493-E1005493(2015).
CC   -!- FUNCTION: RNA-binding nucleolar protein required for pre-rRNA
CC       processing. Involved in production of 18S rRNA and assembly of small
CC       ribosomal subunit (By similarity). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus, nucleolus {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the NOP9 family. {ECO:0000305}.
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DR   EMBL; GG657451; OAT06704.1; -; Genomic_DNA.
DR   RefSeq; XP_002626695.1; XM_002626649.1.
DR   AlphaFoldDB; C5JK19; -.
DR   SMR; C5JK19; -.
DR   STRING; 559298.C5JK19; -.
DR   PRIDE; C5JK19; -.
DR   EnsemblFungi; OAT06704; OAT06704; BDBG_02872.
DR   GeneID; 8510002; -.
DR   KEGG; bgh:BDBG_02872; -.
DR   VEuPathDB; FungiDB:BDBG_02872; -.
DR   HOGENOM; CLU_008720_1_1_1; -.
DR   Proteomes; UP000002038; Unassembled WGS sequence.
DR   GO; GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR   GO; GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.
DR   Gene3D; 1.25.10.10; -; 3.
DR   InterPro; IPR011989; ARM-like.
DR   InterPro; IPR016024; ARM-type_fold.
DR   InterPro; IPR040000; NOP9.
DR   InterPro; IPR001313; Pumilio_RNA-bd_rpt.
DR   PANTHER; PTHR13102; PTHR13102; 1.
DR   SMART; SM00025; Pumilio; 5.
DR   SUPFAM; SSF48371; SSF48371; 1.
PE   3: Inferred from homology;
KW   Nucleus; Reference proteome; Repeat; Ribosome biogenesis; rRNA processing.
FT   CHAIN           1..682
FT                   /note="Nucleolar protein 9"
FT                   /id="PRO_0000407792"
FT   REPEAT          108..143
FT                   /note="Pumilio 1"
FT   REPEAT          347..382
FT                   /note="Pumilio 2"
FT   REPEAT          383..419
FT                   /note="Pumilio 3"
FT   REPEAT          524..562
FT                   /note="Pumilio 4"
FT   REPEAT          563..600
FT                   /note="Pumilio 5"
FT   REGION          1..46
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          249..272
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1..37
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        249..270
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   682 AA;  76477 MW;  179FED85FD8DCDB6 CRC64;
     MPRERQKRGR RAEAKRKRDD EVGDRTAPKR QKASEGDNDF NPLHSQAKIG DDYIPLEEEP
     ASSMDTPFYG LLDPDEQEYF SHASGLLELN QFETEEEKSI FIERVYEEAD GKELKIACSQ
     SCSRLMEKLI SASTVSQIKS LFNKFVGQFL NLVQHRFASH CCESLFLRAA PYVTLEMKKN
     SAEKNDNECE DSSANLRLED LFLAVLSELE GNWGYLLTER FASHTIRVLL LILAGEQLDN
     PSKATVIASR KKENLDKPKV TQRDKSASDR RAVPPSFNAA LEKMMNDLVT GLDNTYLRAL
     ATHPVGNPVL QVLLSVELTH LGKSKARDPD SVFRRLVPDE NLEEGSESAA FIKGLFYDPV
     GSRLLETMVQ LAPGKFFKTF YKALVLERIG SLSRNEIAGH VVARILERLS KEDLKSSMDL
     ILPEVLSLVK RSRFTVIKTL IERGVIRGVD LRPLADSLLL AFGTDPIARI NNVLKLHHLN
     EENDDTKRSS KNSTPEQLHG SLLAQTMLKA PGPLSELIQS SLLAVTLETL IAIAKDPVAS
     HVLQDALTLP TSTIQFRRQI TSRFSGKMAE LALDSSGSHV VDAVWSATEN LIFIKQRFAE
     ELLANERPLR DSFVGRAVWK NWSMDLYKRR RGHWIAVAKG LESVNPSNSE NRQPPKSNLD
     LARARFAEKS NTSTPKKISA TF
 
 
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