ID   NOP9_CANAW              Reviewed;         715 AA.
AC   C4YEN2;
DT   03-MAY-2011, integrated into UniProtKB/Swiss-Prot.
DT   28-JUL-2009, sequence version 1.
DT   25-MAY-2022, entry version 47.
DE   RecName: Full=Nucleolar protein 9;
DE   AltName: Full=Pumilio domain-containing protein NOP9;
GN   Name=NOP9; ORFNames=CAWG_00989;
OS   Candida albicans (strain WO-1) (Yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Debaryomycetaceae; Candida/Lodderomyces clade; Candida.
OX   NCBI_TaxID=294748;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=WO-1;
RX   PubMed=19465905; DOI=10.1038/nature08064;
RA   Butler G., Rasmussen M.D., Lin M.F., Santos M.A.S., Sakthikumar S.,
RA   Munro C.A., Rheinbay E., Grabherr M., Forche A., Reedy J.L., Agrafioti I.,
RA   Arnaud M.B., Bates S., Brown A.J.P., Brunke S., Costanzo M.C.,
RA   Fitzpatrick D.A., de Groot P.W.J., Harris D., Hoyer L.L., Hube B.,
RA   Klis F.M., Kodira C., Lennard N., Logue M.E., Martin R., Neiman A.M.,
RA   Nikolaou E., Quail M.A., Quinn J., Santos M.C., Schmitzberger F.F.,
RA   Sherlock G., Shah P., Silverstein K.A.T., Skrzypek M.S., Soll D.,
RA   Staggs R., Stansfield I., Stumpf M.P.H., Sudbery P.E., Srikantha T.,
RA   Zeng Q., Berman J., Berriman M., Heitman J., Gow N.A.R., Lorenz M.C.,
RA   Birren B.W., Kellis M., Cuomo C.A.;
RT   "Evolution of pathogenicity and sexual reproduction in eight Candida
RT   genomes.";
RL   Nature 459:657-662(2009).
CC   -!- FUNCTION: RNA-binding nucleolar protein required for pre-rRNA
CC       processing. Involved in production of 18S rRNA and assembly of small
CC       ribosomal subunit (By similarity). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus, nucleolus {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the NOP9 family. {ECO:0000305}.
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DR   EMBL; CH672346; EEQ42768.1; -; Genomic_DNA.
DR   AlphaFoldDB; C4YEN2; -.
DR   SMR; C4YEN2; -.
DR   STRING; 5476.C4YEN2; -.
DR   EnsemblFungi; EEQ42768; EEQ42768; CAWG_00989.
DR   VEuPathDB; FungiDB:CAWG_00989; -.
DR   HOGENOM; CLU_008720_1_1_1; -.
DR   OMA; IWDELGS; -.
DR   Proteomes; UP000001429; Chromosome 1, Supercontig 1.1.
DR   GO; GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR   GO; GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.
DR   Gene3D; 1.25.10.10; -; 3.
DR   InterPro; IPR011989; ARM-like.
DR   InterPro; IPR016024; ARM-type_fold.
DR   InterPro; IPR040000; NOP9.
DR   InterPro; IPR001313; Pumilio_RNA-bd_rpt.
DR   PANTHER; PTHR13102; PTHR13102; 1.
DR   SMART; SM00025; Pumilio; 8.
DR   SUPFAM; SSF48371; SSF48371; 1.
DR   PROSITE; PS50302; PUM; 7.
PE   3: Inferred from homology;
KW   Nucleus; Repeat; Ribosome biogenesis; rRNA processing.
FT   CHAIN           1..715
FT                   /note="Nucleolar protein 9"
FT                   /id="PRO_0000407804"
FT   REPEAT          95..130
FT                   /note="Pumilio 1"
FT   REPEAT          131..166
FT                   /note="Pumilio 2"
FT   REPEAT          201..237
FT                   /note="Pumilio 3"
FT   REPEAT          285..326
FT                   /note="Pumilio 4"
FT   REPEAT          334..372
FT                   /note="Pumilio 5"
FT   REPEAT          374..410
FT                   /note="Pumilio 6"
FT   REPEAT          525..562
FT                   /note="Pumilio 7"
FT   REPEAT          567..605
FT                   /note="Pumilio 8"
FT   REGION          1..30
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          651..715
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        651..707
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   715 AA;  82775 MW;  FCDC01D123DE7FE3 CRC64;
     MGKTKSRGRR AEKKNKKNEP GFNEDVSNLD SDVTITNQEP LSSSISSTSG IPNTFFGLVD
     NNELDYFKQA ESTLNINAFE TDEERQGFIN SVLDEAQGKE LKLVTNQICS KLMERLILFA
     NHNQLKKIFK QFQNHFVSLA FHKYASHVLE TLLVRSAALI EKELTQTDEE KLEKAEEEEA
     EENSLNNDVP MEDLFISMLN EFKPHLTTMI DHSYASHVLR LLILILAGKE LPSSVTSNST
     LRSKKSKIAR KMIEIKDNED FDRAFQTPQS FKNELREYCQ TIIAGLDTKS ARELSIHKIG
     SPVLQLLIQV EGLVDRERSF WHLIFAKDSE GKDSVEESFV EYLLSESVGS HFLESIIKND
     GARPKYIERL YKLYMKDRVL KLAKRSTTGV YIIQALLFKL KPVEVEYILD QIIPELAELI
     SIAENQNLDL ANKLIDASIS RGNYRRDEII NQLFIKFAPN YDIENPSDNT STEFIENILQ
     LTGSTLGNTR DDWPTAEERK RALFLEKLME YDYKCVICTW FNFMALPIER FVQMCFHGVF
     CHVVEKALIV EPEEPKPIQI LRKRLLNIFQ GQIVGLACNS YGSHIVDSLW NFTVLLPMYK
     DRIASELLGD SHRVKESTYG RLVWKNWGME LFVRKKYDWK ALIKQQEQEY YGETEDSTEK
     RTKKPIELKM ERLAEEKRRQ EEMAERAQSG YTKRKLEEAT GTASEKKQKL RGRRR