NOP9_CANGA
ID NOP9_CANGA Reviewed; 665 AA.
AC Q6FUX0;
DT 03-MAY-2011, integrated into UniProtKB/Swiss-Prot.
DT 19-JUL-2004, sequence version 1.
DT 03-AUG-2022, entry version 95.
DE RecName: Full=Nucleolar protein 9;
DE AltName: Full=Pumilio domain-containing protein NOP9;
GN Name=NOP9; OrderedLocusNames=CAGL0E06534g;
OS Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL
OS Y-65) (Yeast) (Torulopsis glabrata).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Saccharomycetaceae; Nakaseomyces;
OC Nakaseomyces/Candida clade.
OX NCBI_TaxID=284593;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65;
RX PubMed=15229592; DOI=10.1038/nature02579;
RA Dujon B., Sherman D., Fischer G., Durrens P., Casaregola S., Lafontaine I.,
RA de Montigny J., Marck C., Neuveglise C., Talla E., Goffard N., Frangeul L.,
RA Aigle M., Anthouard V., Babour A., Barbe V., Barnay S., Blanchin S.,
RA Beckerich J.-M., Beyne E., Bleykasten C., Boisrame A., Boyer J.,
RA Cattolico L., Confanioleri F., de Daruvar A., Despons L., Fabre E.,
RA Fairhead C., Ferry-Dumazet H., Groppi A., Hantraye F., Hennequin C.,
RA Jauniaux N., Joyet P., Kachouri R., Kerrest A., Koszul R., Lemaire M.,
RA Lesur I., Ma L., Muller H., Nicaud J.-M., Nikolski M., Oztas S.,
RA Ozier-Kalogeropoulos O., Pellenz S., Potier S., Richard G.-F.,
RA Straub M.-L., Suleau A., Swennen D., Tekaia F., Wesolowski-Louvel M.,
RA Westhof E., Wirth B., Zeniou-Meyer M., Zivanovic Y., Bolotin-Fukuhara M.,
RA Thierry A., Bouchier C., Caudron B., Scarpelli C., Gaillardin C.,
RA Weissenbach J., Wincker P., Souciet J.-L.;
RT "Genome evolution in yeasts.";
RL Nature 430:35-44(2004).
CC -!- FUNCTION: RNA-binding nucleolar protein required for pre-rRNA
CC processing. Involved in production of 18S rRNA and assembly of small
CC ribosomal subunit (By similarity). {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Nucleus, nucleolus {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the NOP9 family. {ECO:0000305}.
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DR EMBL; CR380951; CAG58893.1; -; Genomic_DNA.
DR RefSeq; XP_445974.1; XM_445974.1.
DR AlphaFoldDB; Q6FUX0; -.
DR SMR; Q6FUX0; -.
DR STRING; 5478.XP_445974.1; -.
DR EnsemblFungi; CAG58893; CAG58893; CAGL0E06534g.
DR GeneID; 2887295; -.
DR KEGG; cgr:CAGL0E06534g; -.
DR CGD; CAL0128762; CAGL0E06534g.
DR VEuPathDB; FungiDB:CAGL0E06534g; -.
DR eggNOG; KOG2188; Eukaryota.
DR HOGENOM; CLU_008720_1_1_1; -.
DR InParanoid; Q6FUX0; -.
DR OMA; TPNGSHI; -.
DR Proteomes; UP000002428; Chromosome E.
DR GO; GO:0030686; C:90S preribosome; IEA:EnsemblFungi.
DR GO; GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
DR GO; GO:0030688; C:preribosome, small subunit precursor; IEA:EnsemblFungi.
DR GO; GO:0032040; C:small-subunit processome; IEA:EnsemblFungi.
DR GO; GO:0003729; F:mRNA binding; IEA:UniProt.
DR GO; GO:0000480; P:endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); IEA:EnsemblFungi.
DR GO; GO:0000447; P:endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); IEA:EnsemblFungi.
DR GO; GO:0000472; P:endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA); IEA:EnsemblFungi.
DR GO; GO:0017148; P:negative regulation of translation; IEA:UniProt.
DR GO; GO:0065008; P:regulation of biological quality; IEA:UniProt.
DR GO; GO:0000056; P:ribosomal small subunit export from nucleus; IEA:EnsemblFungi.
DR Gene3D; 1.25.10.10; -; 2.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR040000; NOP9.
DR InterPro; IPR033133; PUM-HD.
DR InterPro; IPR001313; Pumilio_RNA-bd_rpt.
DR PANTHER; PTHR13102; PTHR13102; 1.
DR Pfam; PF00806; PUF; 2.
DR SMART; SM00025; Pumilio; 8.
DR SUPFAM; SSF48371; SSF48371; 1.
DR PROSITE; PS50303; PUM_HD; 1.
PE 3: Inferred from homology;
KW Nucleus; Reference proteome; Repeat; Ribosome biogenesis; rRNA processing.
FT CHAIN 1..665
FT /note="Nucleolar protein 9"
FT /id="PRO_0000407806"
FT REPEAT 87..122
FT /note="Pumilio 1"
FT REPEAT 123..158
FT /note="Pumilio 2"
FT REPEAT 187..228
FT /note="Pumilio 3"
FT REPEAT 285..321
FT /note="Pumilio 4"
FT REPEAT 333..368
FT /note="Pumilio 5"
FT REPEAT 370..406
FT /note="Pumilio 6"
FT REPEAT 510..547
FT /note="Pumilio 7"
FT REPEAT 548..586
FT /note="Pumilio 8"
FT REGION 1..42
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 8..33
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 665 AA; 77401 MW; 68BD0915798F2A7B CRC64;
MGKPRGRKLE KKIKDQEFHP EQDSEKISEN YNYDGHPESD TSNPQMFFGV LDRDELEYFK
QTEATLSLDT FETEEEKAQF VTNVIQEAEG KELKLVTSQI CSKLMERLIL NCNDIQLKKL
FQAFNGNFYN ISCHKYASHV VETLLVRSAS LVEKELITPH FDNMDASVDG SDVFAPMESL
FLFMLNEIKP HLKSMINHQY ASHVLRLIIL ILSSKTLPST TQNNSIVRSK KSKIARKMID
LKDNEDFNKV YQTPESFKSE LKMMLNDLYS DLTGHAKPKA EINPTVITKF REFCVDKVAS
PVIQLIIQVE GIFDRDRSFW RLAFNTNDEK DAKEQSFMEY LLSDPVGSHF LENVISFAKT
KYVERLYRVY IKDQIVRLAK RDTTGAFVIQ SLLKNMKDKE VKEILDALLP DLSILLNSNM
DFGTTIINAC IKQNNYKRDE VIGQLMKKYY PDGSSEKNIL ESCLLLASST LGNTKDDWPT
AEERRRSIFL EELIDFDDKF LEVAIESMLN LPEERLLQMC YHGVFSHVVE HVLQVQRVDI
IKRKLLLNIL IKDIVKLACN AYGSHIVDKL WDFTAKLTLY KERIAAALVE NSEMVKNSVY
GRQVWKNWQL EKYIRKRWEW KKIIKESDLE TFPNMRVLQP NMQERAAIKR KNDDKAFDSM
KKSRK
