ID   NOP9_CLAL4              Reviewed;         715 AA.
AC   C4Y3N8;
DT   03-MAY-2011, integrated into UniProtKB/Swiss-Prot.
DT   28-JUL-2009, sequence version 1.
DT   25-MAY-2022, entry version 49.
DE   RecName: Full=Nucleolar protein 9;
DE   AltName: Full=Pumilio domain-containing protein NOP9;
GN   Name=NOP9; ORFNames=CLUG_03151;
OS   Clavispora lusitaniae (strain ATCC 42720) (Yeast) (Candida lusitaniae).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Metschnikowiaceae; Clavispora.
OX   NCBI_TaxID=306902;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 42720;
RX   PubMed=19465905; DOI=10.1038/nature08064;
RA   Butler G., Rasmussen M.D., Lin M.F., Santos M.A.S., Sakthikumar S.,
RA   Munro C.A., Rheinbay E., Grabherr M., Forche A., Reedy J.L., Agrafioti I.,
RA   Arnaud M.B., Bates S., Brown A.J.P., Brunke S., Costanzo M.C.,
RA   Fitzpatrick D.A., de Groot P.W.J., Harris D., Hoyer L.L., Hube B.,
RA   Klis F.M., Kodira C., Lennard N., Logue M.E., Martin R., Neiman A.M.,
RA   Nikolaou E., Quail M.A., Quinn J., Santos M.C., Schmitzberger F.F.,
RA   Sherlock G., Shah P., Silverstein K.A.T., Skrzypek M.S., Soll D.,
RA   Staggs R., Stansfield I., Stumpf M.P.H., Sudbery P.E., Srikantha T.,
RA   Zeng Q., Berman J., Berriman M., Heitman J., Gow N.A.R., Lorenz M.C.,
RA   Birren B.W., Kellis M., Cuomo C.A.;
RT   "Evolution of pathogenicity and sexual reproduction in eight Candida
RT   genomes.";
RL   Nature 459:657-662(2009).
CC   -!- FUNCTION: RNA-binding nucleolar protein required for pre-rRNA
CC       processing. Involved in production of 18S rRNA and assembly of small
CC       ribosomal subunit (By similarity). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus, nucleolus {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the NOP9 family. {ECO:0000305}.
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DR   EMBL; CH408078; EEQ39025.1; -; Genomic_DNA.
DR   RefSeq; XP_002617707.1; XM_002617661.1.
DR   AlphaFoldDB; C4Y3N8; -.
DR   SMR; C4Y3N8; -.
DR   STRING; 306902.C4Y3N8; -.
DR   EnsemblFungi; EEQ39025; EEQ39025; CLUG_03151.
DR   GeneID; 8498109; -.
DR   KEGG; clu:CLUG_03151; -.
DR   VEuPathDB; FungiDB:CLUG_03151; -.
DR   HOGENOM; CLU_008720_1_1_1; -.
DR   InParanoid; C4Y3N8; -.
DR   OMA; TPNGSHI; -.
DR   Proteomes; UP000007703; Unassembled WGS sequence.
DR   GO; GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR   GO; GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.
DR   Gene3D; 1.25.10.10; -; 3.
DR   InterPro; IPR011989; ARM-like.
DR   InterPro; IPR016024; ARM-type_fold.
DR   InterPro; IPR040000; NOP9.
DR   InterPro; IPR001313; Pumilio_RNA-bd_rpt.
DR   PANTHER; PTHR13102; PTHR13102; 1.
DR   SMART; SM00025; Pumilio; 8.
DR   SUPFAM; SSF48371; SSF48371; 1.
DR   PROSITE; PS50302; PUM; 5.
PE   3: Inferred from homology;
KW   Nucleus; Reference proteome; Repeat; Ribosome biogenesis; rRNA processing.
FT   CHAIN           1..715
FT                   /note="Nucleolar protein 9"
FT                   /id="PRO_0000407808"
FT   REPEAT          99..134
FT                   /note="Pumilio 1"
FT   REPEAT          135..170
FT                   /note="Pumilio 2"
FT   REPEAT          206..243
FT                   /note="Pumilio 3"
FT   REPEAT          291..326
FT                   /note="Pumilio 4"
FT   REPEAT          340..377
FT                   /note="Pumilio 5"
FT   REPEAT          379..415
FT                   /note="Pumilio 6"
FT   REPEAT          531..568
FT                   /note="Pumilio 7"
FT   REPEAT          575..613
FT                   /note="Pumilio 8"
FT   REGION          1..52
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          688..715
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        8..23
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        688..706
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   715 AA;  82601 MW;  0DB81AB71094E2FE CRC64;
     MPKPRGRRVQ SAFKERVENS EATHENSIAE TGSDVEISLH EDQPQTSDNK NQGEFSSVFY
     GLVDSAEIDY FKQAESTLNA NVFESDEDRA GFIRSVLEES RGKELKLVTN QICSKLMERL
     VLLASDRQLK HIFHQFLGHF PALAHHKYSS HVLETLLVRS AALIEKEIVN EYQQDEEDQD
     ENADNDEDNF VASTTMESMF LQMLDQLEPY WSSMIQHQYA SHVMRIIILI VSGKELPSST
     MANSVLRSKK SKVARKMIEI KDNEDFNRAY QVPSSFKDRL RTIISAVSSP LDTKSARSLA
     IHKVASPVLQ LIIRVEGIVD KERSVWHLIF LSEKAPKDSS EEAFVEYLLS DSVGSHFLEA
     IIKNDGARMK YIERLYRLYM KDRVLKLARR ATTGVYIIQA LLLKLKPGEV EHILDEIIPE
     LSSLISISES QNIDLGKAII DASISRFNYR RDELIEQLFQ KFAPNYNVSD PSEDTTTELF
     ENVLQLASST LGNTRDDWPT AEERRRSLFL EKLMQYDYSF VVCVWLNCMA LPQERLMQMC
     FHGVFSHVIE HALVVKPASE GEPKEVLILR KKFLNLFQGK IFELACNSYG SHIVDKLWDF
     TVLLPMYKDR IASEMMAQAN RVKDSTYGRL VWKNWSMELF VRKKYDWKVL VKEQEENYYA
     EEGTQGDAMK KKKPIELKME EIFKKKQYQE ERAKREGEDL AGSNQKRMKG RGRNR