ID   NOP9_COCP7              Reviewed;         722 AA.
AC   C5P9D1;
DT   03-MAY-2011, integrated into UniProtKB/Swiss-Prot.
DT   03-MAY-2011, sequence version 2.
DT   25-MAY-2022, entry version 57.
DE   RecName: Full=Nucleolar protein 9;
DE   AltName: Full=Pumilio domain-containing protein NOP9;
GN   Name=NOP9; ORFNames=CPC735_005150;
OS   Coccidioides posadasii (strain C735) (Valley fever fungus).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Onygenales; Onygenaceae; Coccidioides.
OX   NCBI_TaxID=222929;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=C735;
RX   PubMed=19717792; DOI=10.1101/gr.087551.108;
RA   Sharpton T.J., Stajich J.E., Rounsley S.D., Gardner M.J., Wortman J.R.,
RA   Jordar V.S., Maiti R., Kodira C.D., Neafsey D.E., Zeng Q., Hung C.-Y.,
RA   McMahan C., Muszewska A., Grynberg M., Mandel M.A., Kellner E.M.,
RA   Barker B.M., Galgiani J.N., Orbach M.J., Kirkland T.N., Cole G.T.,
RA   Henn M.R., Birren B.W., Taylor J.W.;
RT   "Comparative genomic analyses of the human fungal pathogens Coccidioides
RT   and their relatives.";
RL   Genome Res. 19:1722-1731(2009).
CC   -!- FUNCTION: RNA-binding nucleolar protein required for pre-rRNA
CC       processing. Involved in production of 18S rRNA and assembly of small
CC       ribosomal subunit (By similarity). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus, nucleolus {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the NOP9 family. {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=EER26343.1; Type=Erroneous initiation; Note=Extended N-terminus.; Evidence={ECO:0000305};
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DR   EMBL; ACFW01000030; EER26343.1; ALT_INIT; Genomic_DNA.
DR   RefSeq; XP_003068488.1; XM_003068442.1.
DR   AlphaFoldDB; C5P9D1; -.
DR   SMR; C5P9D1; -.
DR   EnsemblFungi; EER26343; EER26343; CPC735_005150.
DR   GeneID; 9693971; -.
DR   KEGG; cpw:CPC735_005150; -.
DR   HOGENOM; CLU_008720_1_1_1; -.
DR   Proteomes; UP000009084; Unassembled WGS sequence.
DR   GO; GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR   GO; GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.
DR   Gene3D; 1.25.10.10; -; 3.
DR   InterPro; IPR011989; ARM-like.
DR   InterPro; IPR016024; ARM-type_fold.
DR   InterPro; IPR040000; NOP9.
DR   InterPro; IPR001313; Pumilio_RNA-bd_rpt.
DR   PANTHER; PTHR13102; PTHR13102; 1.
DR   Pfam; PF00806; PUF; 1.
DR   SMART; SM00025; Pumilio; 7.
DR   SUPFAM; SSF48371; SSF48371; 1.
PE   3: Inferred from homology;
KW   Nucleus; Repeat; Ribosome biogenesis; rRNA processing.
FT   CHAIN           1..722
FT                   /note="Nucleolar protein 9"
FT                   /id="PRO_0000407809"
FT   REPEAT          113..152
FT                   /note="Pumilio 1"
FT   REPEAT          153..188
FT                   /note="Pumilio 2"
FT   REPEAT          303..339
FT                   /note="Pumilio 3"
FT   REPEAT          357..392
FT                   /note="Pumilio 4"
FT   REPEAT          393..429
FT                   /note="Pumilio 5"
FT   REPEAT          535..573
FT                   /note="Pumilio 6"
FT   REPEAT          574..611
FT                   /note="Pumilio 7"
FT   REGION          1..54
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          187..207
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          684..722
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1..43
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        684..709
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   722 AA;  80347 MW;  EEB91F775EFC9671 CRC64;
     MPRERQKRGR RAEAKKDKDS QKRKRGHEAT EAEITKRQKI QGDESSEVPV PHDSVFGHGD
     DYIPLEEEAA PVDDTPFYGL LDSDEQEYFS RANQTLELNQ FENDEDRQLF IDSVLQEAGG
     KELKIACSQS CSRLMEKLIS MSSASQLKQL FGKFSGHFLH LVQHRFASHC CERLFLRAAP
     IVTYESKPRT KKGDDAEENQ DGGESASSLP MADLVLNAIS ELEGNWGYLL TESFASHTIR
     VLLLILAGKS LDNSSNIAVV ASRKKENFDA FKTDPQSSSG KRSVPPVFQD ALEKMINGLV
     AGLDTTYLRA LATHPVGSPV LQVLLAVELT HLGKDRAKDP NSVLRRLIPD DSLENTESAT
     FINGLFYDPV GSRLLETLFQ HVPGKFFKMI YKSIVRERIG SLSRNEIASY VAVRVLERLS
     KEDLQATMDT ILREVPSMVE RSRLNVIKAL IERGAVRGAN LTPLANTLKS AYGEEAVSRL
     KKILKLDEAS EPSKEDPTKS ATNLPSQQLH GSLLAQAMLR VPGPLAEMIR SSFLEATVPF
     LLDIAKSPTG SRVLQESLIF SKATGQFRRQ IIPKFSGHLC ELALNTSGSH VVDILWQATS
     DLLFLKQRLA DELVANEKAL RDSFLGRAVW RNWSMDLYKR KRGEWISRAK GLDLNASTAD
     SSNNEQVTKP KSKLDLARER FAAQVEEKAR KPESENPKGK EEIKAGKKRK PAALSAKSLL
     SA