ID   NOP9_DEBHA              Reviewed;         720 AA.
AC   Q6BRH3;
DT   03-MAY-2011, integrated into UniProtKB/Swiss-Prot.
DT   04-NOV-2008, sequence version 2.
DT   03-AUG-2022, entry version 91.
DE   RecName: Full=Nucleolar protein 9;
DE   AltName: Full=Pumilio domain-containing protein NOP9;
GN   Name=NOP9; OrderedLocusNames=DEHA2D16368g;
OS   Debaryomyces hansenii (strain ATCC 36239 / CBS 767 / BCRC 21394 / JCM 1990
OS   / NBRC 0083 / IGC 2968) (Yeast) (Torulaspora hansenii).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Debaryomycetaceae; Debaryomyces.
OX   NCBI_TaxID=284592;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 36239 / CBS 767 / BCRC 21394 / JCM 1990 / NBRC 0083 / IGC 2968;
RX   PubMed=15229592; DOI=10.1038/nature02579;
RA   Dujon B., Sherman D., Fischer G., Durrens P., Casaregola S., Lafontaine I.,
RA   de Montigny J., Marck C., Neuveglise C., Talla E., Goffard N., Frangeul L.,
RA   Aigle M., Anthouard V., Babour A., Barbe V., Barnay S., Blanchin S.,
RA   Beckerich J.-M., Beyne E., Bleykasten C., Boisrame A., Boyer J.,
RA   Cattolico L., Confanioleri F., de Daruvar A., Despons L., Fabre E.,
RA   Fairhead C., Ferry-Dumazet H., Groppi A., Hantraye F., Hennequin C.,
RA   Jauniaux N., Joyet P., Kachouri R., Kerrest A., Koszul R., Lemaire M.,
RA   Lesur I., Ma L., Muller H., Nicaud J.-M., Nikolski M., Oztas S.,
RA   Ozier-Kalogeropoulos O., Pellenz S., Potier S., Richard G.-F.,
RA   Straub M.-L., Suleau A., Swennen D., Tekaia F., Wesolowski-Louvel M.,
RA   Westhof E., Wirth B., Zeniou-Meyer M., Zivanovic Y., Bolotin-Fukuhara M.,
RA   Thierry A., Bouchier C., Caudron B., Scarpelli C., Gaillardin C.,
RA   Weissenbach J., Wincker P., Souciet J.-L.;
RT   "Genome evolution in yeasts.";
RL   Nature 430:35-44(2004).
CC   -!- FUNCTION: RNA-binding nucleolar protein required for pre-rRNA
CC       processing. Involved in production of 18S rRNA and assembly of small
CC       ribosomal subunit (By similarity). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus, nucleolus {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the NOP9 family. {ECO:0000305}.
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DR   EMBL; CR382136; CAG87368.2; -; Genomic_DNA.
DR   RefSeq; XP_459197.2; XM_459197.1.
DR   AlphaFoldDB; Q6BRH3; -.
DR   SMR; Q6BRH3; -.
DR   STRING; 4959.XP_459197.2; -.
DR   EnsemblFungi; CAG87368; CAG87368; DEHA2D16368g.
DR   GeneID; 2901579; -.
DR   KEGG; dha:DEHA2D16368g; -.
DR   VEuPathDB; FungiDB:DEHA2D16368g; -.
DR   eggNOG; KOG2188; Eukaryota.
DR   HOGENOM; CLU_008720_1_1_1; -.
DR   InParanoid; Q6BRH3; -.
DR   OMA; TPNGSHI; -.
DR   OrthoDB; 238378at2759; -.
DR   Proteomes; UP000000599; Chromosome D.
DR   GO; GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003729; F:mRNA binding; IEA:UniProt.
DR   GO; GO:0017148; P:negative regulation of translation; IEA:UniProt.
DR   GO; GO:0065008; P:regulation of biological quality; IEA:UniProt.
DR   GO; GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.
DR   Gene3D; 1.25.10.10; -; 3.
DR   InterPro; IPR011989; ARM-like.
DR   InterPro; IPR016024; ARM-type_fold.
DR   InterPro; IPR040000; NOP9.
DR   InterPro; IPR033133; PUM-HD.
DR   InterPro; IPR001313; Pumilio_RNA-bd_rpt.
DR   PANTHER; PTHR13102; PTHR13102; 1.
DR   SMART; SM00025; Pumilio; 8.
DR   SUPFAM; SSF48371; SSF48371; 1.
DR   PROSITE; PS50302; PUM; 6.
DR   PROSITE; PS50303; PUM_HD; 1.
PE   3: Inferred from homology;
KW   Nucleus; Reference proteome; Repeat; Ribosome biogenesis; rRNA processing.
FT   CHAIN           1..720
FT                   /note="Nucleolar protein 9"
FT                   /id="PRO_0000407812"
FT   REPEAT          90..125
FT                   /note="Pumilio 1"
FT   REPEAT          126..161
FT                   /note="Pumilio 2"
FT   REPEAT          198..234
FT                   /note="Pumilio 3"
FT   REPEAT          278..318
FT                   /note="Pumilio 4"
FT   REPEAT          332..369
FT                   /note="Pumilio 5"
FT   REPEAT          371..407
FT                   /note="Pumilio 6"
FT   REPEAT          523..560
FT                   /note="Pumilio 7"
FT   REPEAT          567..605
FT                   /note="Pumilio 8"
FT   REGION          1..40
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          680..720
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1..20
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        680..714
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   720 AA;  83680 MW;  9F6ACCD2416BA3ED CRC64;
     MVQPKVRGRR AEKKSKEVNT QPEDYSPNDR SELEENDDKV ESNPALKTTF FGLVDSNEID
     YFKQAESTLN VNAFDNDEER EGFIRSVLEE ARGKELKLVT NQICSKLMER LVLFATDRQL
     KNIFRQFSGH FVALAHHKYS SHVLETLLVR AAALIEKELV NDFKQDEGEV DDEISQDNDR
     EDEAVVSMET LFVKMLDEFN PHLKTMVDHQ YSSHVLRLLI LIIAGKELPS TTTSNSTLRS
     KKSKIARKMI EIKDNDDFNR SFQTPPSFKD QLRKLCNSLG SKGDMKHMRE LAINKVASPV
     LQLLIQVEGI VDKERTFWHL IFLSENSDKN PQEEAFVEYL LSDSVGSHFL ESVIRNGGAR
     MKYIERLYKL YMKDRVLKLS KRSTTGVFII QALLFKLKPA EVLFILDQII PELASLISID
     ENQNLELGKN IIDASISRDN YRREELIEQL FVKFAPNYDR HNPSADTSSE FLENTLHLTG
     STLGNTRDDW PTAQERRRSL FLEKLMEYDH SFVVCTWLNF LALPIARFIQ MCYHGVFSHV
     VENSLVVIPA SEGEPKSVLI IRKRFLNLFQ NEIVNLACNS YGSHIVDRLW NFTVLLNMYK
     DRIGSELASE SHKVKESTYG RLVWKNWSME LFVRKKFDWK SLVKNQEEEY FGVGSHEGQN
     STERVKKPIE LKFEQMMKEK QMKEERAQKA EEGFNKRKNN EFEYGYDNDN KKAKIRGRNR