ID   NOP9_EMENI              Reviewed;         699 AA.
AC   Q5B3J5; C8V9T4;
DT   03-MAY-2011, integrated into UniProtKB/Swiss-Prot.
DT   03-MAY-2011, sequence version 2.
DT   25-MAY-2022, entry version 100.
DE   RecName: Full=Nucleolar protein 9;
DE   AltName: Full=Pumilio domain-containing protein nop9;
GN   Name=nop9; ORFNames=AN10618;
OS   Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 /
OS   M139) (Aspergillus nidulans).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus;
OC   Aspergillus subgen. Nidulantes.
OX   NCBI_TaxID=227321;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139;
RX   PubMed=16372000; DOI=10.1038/nature04341;
RA   Galagan J.E., Calvo S.E., Cuomo C., Ma L.-J., Wortman J.R., Batzoglou S.,
RA   Lee S.-I., Bastuerkmen M., Spevak C.C., Clutterbuck J., Kapitonov V.,
RA   Jurka J., Scazzocchio C., Farman M.L., Butler J., Purcell S., Harris S.,
RA   Braus G.H., Draht O., Busch S., D'Enfert C., Bouchier C., Goldman G.H.,
RA   Bell-Pedersen D., Griffiths-Jones S., Doonan J.H., Yu J., Vienken K.,
RA   Pain A., Freitag M., Selker E.U., Archer D.B., Penalva M.A., Oakley B.R.,
RA   Momany M., Tanaka T., Kumagai T., Asai K., Machida M., Nierman W.C.,
RA   Denning D.W., Caddick M.X., Hynes M., Paoletti M., Fischer R., Miller B.L.,
RA   Dyer P.S., Sachs M.S., Osmani S.A., Birren B.W.;
RT   "Sequencing of Aspergillus nidulans and comparative analysis with A.
RT   fumigatus and A. oryzae.";
RL   Nature 438:1105-1115(2005).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139;
RX   PubMed=19146970; DOI=10.1016/j.fgb.2008.12.003;
RA   Wortman J.R., Gilsenan J.M., Joardar V., Deegan J., Clutterbuck J.,
RA   Andersen M.R., Archer D., Bencina M., Braus G., Coutinho P., von Dohren H.,
RA   Doonan J., Driessen A.J., Durek P., Espeso E., Fekete E., Flipphi M.,
RA   Estrada C.G., Geysens S., Goldman G., de Groot P.W., Hansen K.,
RA   Harris S.D., Heinekamp T., Helmstaedt K., Henrissat B., Hofmann G.,
RA   Homan T., Horio T., Horiuchi H., James S., Jones M., Karaffa L.,
RA   Karanyi Z., Kato M., Keller N., Kelly D.E., Kiel J.A., Kim J.M.,
RA   van der Klei I.J., Klis F.M., Kovalchuk A., Krasevec N., Kubicek C.P.,
RA   Liu B., Maccabe A., Meyer V., Mirabito P., Miskei M., Mos M., Mullins J.,
RA   Nelson D.R., Nielsen J., Oakley B.R., Osmani S.A., Pakula T., Paszewski A.,
RA   Paulsen I., Pilsyk S., Pocsi I., Punt P.J., Ram A.F., Ren Q., Robellet X.,
RA   Robson G., Seiboth B., van Solingen P., Specht T., Sun J.,
RA   Taheri-Talesh N., Takeshita N., Ussery D., vanKuyk P.A., Visser H.,
RA   van de Vondervoort P.J., de Vries R.P., Walton J., Xiang X., Xiong Y.,
RA   Zeng A.P., Brandt B.W., Cornell M.J., van den Hondel C.A., Visser J.,
RA   Oliver S.G., Turner G.;
RT   "The 2008 update of the Aspergillus nidulans genome annotation: a community
RT   effort.";
RL   Fungal Genet. Biol. 46:S2-13(2009).
CC   -!- FUNCTION: RNA-binding nucleolar protein required for pre-rRNA
CC       processing. Involved in production of 18S rRNA and assembly of small
CC       ribosomal subunit (By similarity). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus, nucleolus {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the NOP9 family. {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=EAA60963.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AACD01000084; EAA60963.1; ALT_SEQ; Genomic_DNA.
DR   EMBL; BN001303; CBF76553.1; -; Genomic_DNA.
DR   RefSeq; XP_662489.1; XM_657397.1.
DR   AlphaFoldDB; Q5B3J5; -.
DR   SMR; Q5B3J5; -.
DR   STRING; 162425.CADANIAP00005519; -.
DR   EnsemblFungi; CBF76553; CBF76553; ANIA_10618.
DR   EnsemblFungi; EAA60963; EAA60963; AN4885.2.
DR   GeneID; 2872681; -.
DR   KEGG; ani:AN4885.2; -.
DR   VEuPathDB; FungiDB:AN10618; -.
DR   eggNOG; KOG2188; Eukaryota.
DR   HOGENOM; CLU_002310_0_0_1; -.
DR   InParanoid; Q5B3J5; -.
DR   OMA; TPNGSHI; -.
DR   OrthoDB; 47788at2759; -.
DR   Proteomes; UP000000560; Chromosome III.
DR   Proteomes; UP000005890; Unassembled WGS sequence.
DR   GO; GO:0030686; C:90S preribosome; IBA:GO_Central.
DR   GO; GO:0005730; C:nucleolus; IBA:GO_Central.
DR   GO; GO:0030688; C:preribosome, small subunit precursor; IBA:GO_Central.
DR   GO; GO:0003723; F:RNA binding; IBA:GO_Central.
DR   GO; GO:0000480; P:endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); IBA:GO_Central.
DR   GO; GO:0000447; P:endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); IBA:GO_Central.
DR   GO; GO:0000472; P:endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA); IBA:GO_Central.
DR   GO; GO:0000056; P:ribosomal small subunit export from nucleus; IBA:GO_Central.
DR   Gene3D; 1.25.10.10; -; 2.
DR   InterPro; IPR011989; ARM-like.
DR   InterPro; IPR016024; ARM-type_fold.
DR   InterPro; IPR040000; NOP9.
DR   InterPro; IPR001313; Pumilio_RNA-bd_rpt.
DR   PANTHER; PTHR13102; PTHR13102; 1.
DR   Pfam; PF00806; PUF; 1.
DR   SMART; SM00025; Pumilio; 6.
DR   SUPFAM; SSF48371; SSF48371; 1.
PE   3: Inferred from homology;
KW   Nucleus; Reference proteome; Repeat; Ribosome biogenesis; rRNA processing.
FT   CHAIN           1..699
FT                   /note="Nucleolar protein 9"
FT                   /id="PRO_0000407813"
FT   REPEAT          115..150
FT                   /note="Pumilio 1"
FT   REPEAT          151..186
FT                   /note="Pumilio 2"
FT   REPEAT          359..394
FT                   /note="Pumilio 3"
FT   REPEAT          396..431
FT                   /note="Pumilio 4"
FT   REPEAT          544..581
FT                   /note="Pumilio 5"
FT   REPEAT          583..620
FT                   /note="Pumilio 6"
FT   REGION          1..47
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          184..204
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          494..514
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1..42
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   699 AA;  78520 MW;  C53B143C6F91F073 CRC64;
     MPRENQKRGR RATEKAKKEA SKRKRDEGIE EPTLKRLKPS ADEDNAVTAG ADYVPLEGEE
     YDDQYATGAA DEMPFYGLLD SEEQEYFSRA NEMLELNQFG DAEERRLFVD SVFREARGKE
     LKIACSQSCS RLMEKLISVS DIHQIWRLFN KFIGHFLTLV QHRFASHCCE RLFISAAPGV
     TQKASKTKSK KDDDIEMDED EEPEPELPLA EMFMKVVEEL QGNWGYLLTE RFASHTIRVL
     LLVLAGEPVD VSSNDSVVAS RKKERLGVVG GETQENNPSG EKRSVPESFE ATLKKVMQDM
     VSVLDDTYLR ALATHPVGNP VLQVLVRLEL SHFGKSSAKQ PTSIIKRLIP DENFEDDSET
     TRFIRGLLYD PVGSRLLETM VRCMPGKMFK SLYRNYLRDQ MSSLARNQTA GYVVLRVLER
     LGRDDLHAVM EQIVPKIPSL IERSRTIVPK VLIERCLARG VDTKPIAKAL ESSYDSDPAR
     RLEQMLRLET AMADNKEKSD KNGPPGESNP GSAAAEKLHG SLLAQTIVTA PGQLSELVFS
     SLLALSPEVL LSICKDPTAS RVIQQALTSP ASSPQFRRQF TTRFTSHMNE LALDSSGSHV
     VDALWPATKD IYFIKERMAQ ELAQNELALR DSFVGRAVWR NWAMDLYKRR RGEWAAKAKG
     RDITNDSAEK PKSRLDMARA RYAAKQSEAT GANAVAAKQ