ID   NOP9_KOMPG              Reviewed;         645 AA.
AC   C4R8S9;
DT   03-MAY-2011, integrated into UniProtKB/Swiss-Prot.
DT   07-JUL-2009, sequence version 1.
DT   03-AUG-2022, entry version 62.
DE   RecName: Full=Nucleolar protein 9;
DE   AltName: Full=Pumilio domain-containing protein NOP9;
GN   Name=NOP9; OrderedLocusNames=PAS_chr4_0742;
OS   Komagataella phaffii (strain GS115 / ATCC 20864) (Yeast) (Pichia pastoris).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Phaffomycetaceae; Komagataella.
OX   NCBI_TaxID=644223;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=GS115 / ATCC 20864;
RX   PubMed=19465926; DOI=10.1038/nbt.1544;
RA   De Schutter K., Lin Y.-C., Tiels P., Van Hecke A., Glinka S.,
RA   Weber-Lehmann J., Rouze P., Van de Peer Y., Callewaert N.;
RT   "Genome sequence of the recombinant protein production host Pichia
RT   pastoris.";
RL   Nat. Biotechnol. 27:561-566(2009).
CC   -!- FUNCTION: RNA-binding nucleolar protein required for pre-rRNA
CC       processing. Involved in production of 18S rRNA and assembly of small
CC       ribosomal subunit (By similarity). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus, nucleolus {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the NOP9 family. {ECO:0000305}.
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DR   EMBL; FN392322; CAY72004.1; -; Genomic_DNA.
DR   RefSeq; XP_002494183.1; XM_002494138.1.
DR   AlphaFoldDB; C4R8S9; -.
DR   SMR; C4R8S9; -.
DR   STRING; 644223.C4R8S9; -.
DR   EnsemblFungi; CAY72004; CAY72004; PAS_chr4_0742.
DR   GeneID; 8200635; -.
DR   KEGG; ppa:PAS_chr4_0742; -.
DR   eggNOG; KOG2188; Eukaryota.
DR   HOGENOM; CLU_008720_1_1_1; -.
DR   InParanoid; C4R8S9; -.
DR   OMA; TPNGSHI; -.
DR   Proteomes; UP000000314; Chromosome 4.
DR   GO; GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003729; F:mRNA binding; IEA:UniProt.
DR   GO; GO:0017148; P:negative regulation of translation; IEA:UniProt.
DR   GO; GO:0065008; P:regulation of biological quality; IEA:UniProt.
DR   GO; GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.
DR   Gene3D; 1.25.10.10; -; 3.
DR   InterPro; IPR011989; ARM-like.
DR   InterPro; IPR016024; ARM-type_fold.
DR   InterPro; IPR040000; NOP9.
DR   InterPro; IPR033133; PUM-HD.
DR   InterPro; IPR001313; Pumilio_RNA-bd_rpt.
DR   PANTHER; PTHR13102; PTHR13102; 1.
DR   Pfam; PF00806; PUF; 3.
DR   SMART; SM00025; Pumilio; 8.
DR   SUPFAM; SSF48371; SSF48371; 1.
DR   PROSITE; PS50302; PUM; 6.
DR   PROSITE; PS50303; PUM_HD; 1.
PE   3: Inferred from homology;
KW   Nucleus; Reference proteome; Repeat; Ribosome biogenesis; rRNA processing.
FT   CHAIN           1..645
FT                   /note="Nucleolar protein 9"
FT                   /id="PRO_0000407828"
FT   REPEAT          83..118
FT                   /note="Pumilio 1"
FT   REPEAT          119..154
FT                   /note="Pumilio 2"
FT   REPEAT          183..219
FT                   /note="Pumilio 3"
FT   REPEAT          259..304
FT                   /note="Pumilio 4"
FT   REPEAT          316..351
FT                   /note="Pumilio 5"
FT   REPEAT          353..389
FT                   /note="Pumilio 6"
FT   REPEAT          489..526
FT                   /note="Pumilio 7"
FT   REPEAT          527..564
FT                   /note="Pumilio 8"
FT   REGION          1..33
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          619..645
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1..21
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        619..639
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   645 AA;  74333 MW;  90AC1C90A9AAC7A9 CRC64;
     MAKERGRRNL KKIKESSQSD SLKTLKADPS PSREAAQIDV NTFFGLVNSE ELDYFKQAES
     TLNANAFENS EERQGFVSSV FEEAKGKELK LVTNQICSKL MERLILNGSD RQVKRLFKAF
     NGHFLSLAVH KYSSHVLETL FIRSASVIEN ELLNNYQEEE AEEEESDEVF ATMENMFLFM
     LAELSSSIQK LIVHQYGSHV IRLLLLIVGA RELPSSIMSN SILRSKKSKI ARKMIEIKDN
     QDSNRAYQVP AGFKNELQEL LGLIAKDKDS KQLRELAIDK IASPVIQLCI QLEGLVDKDR
     TIWTTIFPEV DDKDPKEEAF VEYLLSDPIG SHFFQAAIKY QKPKTVHRLY DLYIKDRLLK
     LAKRETTGAF VVKELLGKLK ATDVTEMLDI LIPHLSELIE NNLEIGQAIV DASIARNNYG
     KEGIISQFLK VFNDANVLES VLKLSTSTLG NTKNDWPTAE ERRCAIFLEK LVEYDDSFLD
     AVIAALLELP EDRFIQMCMH GVFSHVVESV LVIERVDIVK RRRLLNIFTE HVVTLSCNAY
     GSHIMDKLWQ FSIKLNLFKD RIALALFENK DKIKDSIYGK LVWKNWSMEL YCRRMYDWKN
     LIKQQELELF PDHRGAPTLL KKRPLEEPKK VEEKKDKSRG RRRYH