ID   NOP9_LACTC              Reviewed;         670 AA.
AC   C5DMC1;
DT   03-MAY-2011, integrated into UniProtKB/Swiss-Prot.
DT   28-JUL-2009, sequence version 1.
DT   25-MAY-2022, entry version 59.
DE   RecName: Full=Nucleolar protein 9;
DE   AltName: Full=Pumilio domain-containing protein NOP9;
GN   Name=NOP9; OrderedLocusNames=KLTH0G07612g;
OS   Lachancea thermotolerans (strain ATCC 56472 / CBS 6340 / NRRL Y-8284)
OS   (Yeast) (Kluyveromyces thermotolerans).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Lachancea.
OX   NCBI_TaxID=559295;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 56472 / CBS 6340 / NRRL Y-8284;
RX   PubMed=19525356; DOI=10.1101/gr.091546.109;
RG   The Genolevures Consortium;
RA   Souciet J.-L., Dujon B., Gaillardin C., Johnston M., Baret P.V.,
RA   Cliften P., Sherman D.J., Weissenbach J., Westhof E., Wincker P., Jubin C.,
RA   Poulain J., Barbe V., Segurens B., Artiguenave F., Anthouard V.,
RA   Vacherie B., Val M.-E., Fulton R.S., Minx P., Wilson R., Durrens P.,
RA   Jean G., Marck C., Martin T., Nikolski M., Rolland T., Seret M.-L.,
RA   Casaregola S., Despons L., Fairhead C., Fischer G., Lafontaine I., Leh V.,
RA   Lemaire M., de Montigny J., Neuveglise C., Thierry A., Blanc-Lenfle I.,
RA   Bleykasten C., Diffels J., Fritsch E., Frangeul L., Goeffon A.,
RA   Jauniaux N., Kachouri-Lafond R., Payen C., Potier S., Pribylova L.,
RA   Ozanne C., Richard G.-F., Sacerdot C., Straub M.-L., Talla E.;
RT   "Comparative genomics of protoploid Saccharomycetaceae.";
RL   Genome Res. 19:1696-1709(2009).
CC   -!- FUNCTION: RNA-binding nucleolar protein required for pre-rRNA
CC       processing. Involved in production of 18S rRNA and assembly of small
CC       ribosomal subunit (By similarity). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus, nucleolus {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the NOP9 family. {ECO:0000305}.
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DR   EMBL; CU928171; CAR24932.1; -; Genomic_DNA.
DR   RefSeq; XP_002555369.1; XM_002555323.1.
DR   AlphaFoldDB; C5DMC1; -.
DR   SMR; C5DMC1; -.
DR   STRING; 559295.C5DMC1; -.
DR   PRIDE; C5DMC1; -.
DR   EnsemblFungi; CAR24932; CAR24932; KLTH0G07612g.
DR   GeneID; 8293639; -.
DR   KEGG; lth:KLTH0G07612g; -.
DR   eggNOG; KOG2188; Eukaryota.
DR   HOGENOM; CLU_008720_1_1_1; -.
DR   InParanoid; C5DMC1; -.
DR   OMA; TPNGSHI; -.
DR   OrthoDB; 238378at2759; -.
DR   Proteomes; UP000002036; Chromosome G.
DR   GO; GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR   GO; GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.
DR   Gene3D; 1.25.10.10; -; 3.
DR   InterPro; IPR011989; ARM-like.
DR   InterPro; IPR016024; ARM-type_fold.
DR   InterPro; IPR040000; NOP9.
DR   InterPro; IPR001313; Pumilio_RNA-bd_rpt.
DR   PANTHER; PTHR13102; PTHR13102; 1.
DR   Pfam; PF00806; PUF; 2.
DR   SMART; SM00025; Pumilio; 8.
DR   SUPFAM; SSF48371; SSF48371; 1.
PE   3: Inferred from homology;
KW   Nucleus; Reference proteome; Repeat; Ribosome biogenesis; rRNA processing.
FT   CHAIN           1..670
FT                   /note="Nucleolar protein 9"
FT                   /id="PRO_0000407815"
FT   REPEAT          89..124
FT                   /note="Pumilio 1"
FT   REPEAT          125..160
FT                   /note="Pumilio 2"
FT   REPEAT          189..225
FT                   /note="Pumilio 3"
FT   REPEAT          289..331
FT                   /note="Pumilio 4"
FT   REPEAT          339..374
FT                   /note="Pumilio 5"
FT   REPEAT          376..412
FT                   /note="Pumilio 6"
FT   REPEAT          517..554
FT                   /note="Pumilio 7"
FT   REPEAT          555..592
FT                   /note="Pumilio 8"
FT   REGION          1..46
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          637..670
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        11..25
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        26..46
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   670 AA;  77088 MW;  DC7D9A3DBCD7130A CRC64;
     MGKPRGRKLL KKHHTEGEEA SHVEPQPYDT NDTIPEKISS GSNGEPNTFF GVLDTQELEY
     FKQAESTLAV DTFENAEEKE QFISSVIEET KNKELKLATS QICSKLMERI ILAGSNQQLK
     AIFRSFNGFF YGLACQKYSS HVLETLFVRG AAMVEKELLT PSFDEPGATE DGDDVYSPME
     DLFLYMLNEI TPSVRGMISH KYASHVFRLL ILILSSKTLP STTMSNSALR SKRSKIARKM
     IDLKDNEDFD KTYKTPDSFK VKLREILSSL YKELTGGVDL GSSNFKNISV TSMMKVRELC
     IDPVASPVLQ LIIQVEGIFD RDRSFWHLIF SSSEEKNAKE EAFVEYLLSD PVGSHFLENV
     ISFTRAKYTE RLYKMYMRDR ILKLSKRDLT GAFVVQALLK HLRQNDVKSI LNDIVPELSL
     IVNSNMEFCI SILDASIQHG DYLKEEIVLQ LIKKFYPEGL EDRNILESCL SLNSSTLGNT
     RDDWPTAEER RRSLFLEKLI DYDDRFLNIT IESLLALPEE RLLQMCYHGV FSHVVEHVLQ
     VKRVDKIKRK RLLNVFCTDI VNLSCNAYGS HLVDKLWDFT AQLPMYKERI ATSMAGDSEK
     VKNSVYGRQA WKNWSMDKFL RKQFDWKRLI REQQQELFPD ATPLQPGGDA GTKRKGDKPS
     YNRPEKKFRR