ID   NOP9_LODEL              Reviewed;         716 AA.
AC   A5DWG1;
DT   03-MAY-2011, integrated into UniProtKB/Swiss-Prot.
DT   12-JUN-2007, sequence version 1.
DT   03-AUG-2022, entry version 66.
DE   RecName: Full=Nucleolar protein 9;
DE   AltName: Full=Pumilio domain-containing protein NOP9;
GN   Name=NOP9; ORFNames=LELG_01697;
OS   Lodderomyces elongisporus (strain ATCC 11503 / CBS 2605 / JCM 1781 / NBRC
OS   1676 / NRRL YB-4239) (Yeast) (Saccharomyces elongisporus).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Debaryomycetaceae; Candida/Lodderomyces clade;
OC   Lodderomyces.
OX   NCBI_TaxID=379508;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 11503 / BCRC 21390 / CBS 2605 / JCM 1781 / NBRC 1676 / NRRL
RC   YB-4239;
RX   PubMed=19465905; DOI=10.1038/nature08064;
RA   Butler G., Rasmussen M.D., Lin M.F., Santos M.A.S., Sakthikumar S.,
RA   Munro C.A., Rheinbay E., Grabherr M., Forche A., Reedy J.L., Agrafioti I.,
RA   Arnaud M.B., Bates S., Brown A.J.P., Brunke S., Costanzo M.C.,
RA   Fitzpatrick D.A., de Groot P.W.J., Harris D., Hoyer L.L., Hube B.,
RA   Klis F.M., Kodira C., Lennard N., Logue M.E., Martin R., Neiman A.M.,
RA   Nikolaou E., Quail M.A., Quinn J., Santos M.C., Schmitzberger F.F.,
RA   Sherlock G., Shah P., Silverstein K.A.T., Skrzypek M.S., Soll D.,
RA   Staggs R., Stansfield I., Stumpf M.P.H., Sudbery P.E., Srikantha T.,
RA   Zeng Q., Berman J., Berriman M., Heitman J., Gow N.A.R., Lorenz M.C.,
RA   Birren B.W., Kellis M., Cuomo C.A.;
RT   "Evolution of pathogenicity and sexual reproduction in eight Candida
RT   genomes.";
RL   Nature 459:657-662(2009).
CC   -!- FUNCTION: RNA-binding nucleolar protein required for pre-rRNA
CC       processing. Involved in production of 18S rRNA and assembly of small
CC       ribosomal subunit (By similarity). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus, nucleolus {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the NOP9 family. {ECO:0000305}.
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DR   EMBL; CH981525; EDK43519.1; -; Genomic_DNA.
DR   RefSeq; XP_001526869.1; XM_001526819.1.
DR   AlphaFoldDB; A5DWG1; -.
DR   SMR; A5DWG1; -.
DR   STRING; 379508.A5DWG1; -.
DR   PRIDE; A5DWG1; -.
DR   EnsemblFungi; EDK43519; EDK43519; LELG_01697.
DR   GeneID; 5233782; -.
DR   KEGG; lel:LELG_01697; -.
DR   VEuPathDB; FungiDB:LELG_01697; -.
DR   eggNOG; KOG2188; Eukaryota.
DR   HOGENOM; CLU_008720_1_1_1; -.
DR   InParanoid; A5DWG1; -.
DR   OMA; IWDELGS; -.
DR   OrthoDB; 238378at2759; -.
DR   Proteomes; UP000001996; Unassembled WGS sequence.
DR   GO; GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR   GO; GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.
DR   Gene3D; 1.25.10.10; -; 2.
DR   InterPro; IPR011989; ARM-like.
DR   InterPro; IPR016024; ARM-type_fold.
DR   InterPro; IPR040000; NOP9.
DR   InterPro; IPR001313; Pumilio_RNA-bd_rpt.
DR   PANTHER; PTHR13102; PTHR13102; 1.
DR   SMART; SM00025; Pumilio; 8.
DR   SUPFAM; SSF48371; SSF48371; 1.
PE   3: Inferred from homology;
KW   Nucleus; Reference proteome; Repeat; Ribosome biogenesis; rRNA processing.
FT   CHAIN           1..716
FT                   /note="Nucleolar protein 9"
FT                   /id="PRO_0000407817"
FT   REPEAT          85..120
FT                   /note="Pumilio 1"
FT   REPEAT          121..156
FT                   /note="Pumilio 2"
FT   REPEAT          204..240
FT                   /note="Pumilio 3"
FT   REPEAT          288..325
FT                   /note="Pumilio 4"
FT   REPEAT          338..375
FT                   /note="Pumilio 5"
FT   REPEAT          377..413
FT                   /note="Pumilio 6"
FT   REPEAT          528..565
FT                   /note="Pumilio 7"
FT   REPEAT          571..608
FT                   /note="Pumilio 8"
FT   REGION          1..38
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          159..188
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          675..716
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        24..38
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        675..709
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   716 AA;  83199 MW;  CC01D99BE15D7BEC CRC64;
     MGKTKSRGRR AEKKEAEKEL LQNAQSLAGE NDSKVSQPSN IPNTFFGLVD STEIEYFKQA
     ESTLNINAFE TDEERNGFIS SVLEEAQGKE LKLVTNQICS KLMERLILFA DSSQLKAIFE
     TFSGHFASLA FHKYSSHVLE TFLVRAAALI ELELTQTDED YNEGHGEERD KDYNEEQERR
     QKVQEQSLSE KKSVEEMFLN MVNELKPYLS TMIDHQYASH VLRLLILILA GKELPSTTTS
     NSTLRSKKSK IARKMIEIKD NEDFDRAYQT PPSFKNELRE YIQIITKDLD TKRARELSIH
     KVASPVLQLI IRVEGLVDRE RTLWHLVFAK QSEEKVPEEE SFVEYLLSDS VGSHFFEGII
     KNDGARPQYI ERLYKLYMKD RVLKLARRAT TGVYIIQALM FKLKPVEVEY ILDIIIPELA
     NLISIADNQN LDLARRIVDA SIIRGNYRRD DIIQQLFLKF APNYDLSNPQ SSTSTEFLEN
     ALQLTGSTLG NTRDDWPTAE ERRRALFLEK LMELDYRFII CAWLNFMALP VERFVQMCMH
     GVFSHVVENA LVVEKDEPKN VQILRKRFLN IFQGNIVTLA CNSYGSHIVD KLWNFTVFLP
     MYKDRVALEL MGEATKVKDS NYGKLVWKNW GMELFARKKY DWKLLIKAQE NEFLGVDEDT
     ERPLKPIELK MNNLARERKE QQERAEQAQM GYNKRKLDEL TGNGEKRQKV RGRRRE