ID   NOP9_NEOFI              Reviewed;         699 AA.
AC   A1D6V7;
DT   03-MAY-2011, integrated into UniProtKB/Swiss-Prot.
DT   23-JAN-2007, sequence version 1.
DT   25-MAY-2022, entry version 78.
DE   RecName: Full=Nucleolar protein 9;
DE   AltName: Full=Pumilio domain-containing protein nop9;
GN   Name=nop9; ORFNames=NFIA_066150;
OS   Neosartorya fischeri (strain ATCC 1020 / DSM 3700 / CBS 544.65 / FGSC A1164
OS   / JCM 1740 / NRRL 181 / WB 181) (Aspergillus fischerianus).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus;
OC   Aspergillus subgen. Fumigati.
OX   NCBI_TaxID=331117;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 1020 / DSM 3700 / CBS 544.65 / FGSC A1164 / JCM 1740 / NRRL 181
RC   / WB 181;
RX   PubMed=18404212; DOI=10.1371/journal.pgen.1000046;
RA   Fedorova N.D., Khaldi N., Joardar V.S., Maiti R., Amedeo P., Anderson M.J.,
RA   Crabtree J., Silva J.C., Badger J.H., Albarraq A., Angiuoli S., Bussey H.,
RA   Bowyer P., Cotty P.J., Dyer P.S., Egan A., Galens K., Fraser-Liggett C.M.,
RA   Haas B.J., Inman J.M., Kent R., Lemieux S., Malavazi I., Orvis J.,
RA   Roemer T., Ronning C.M., Sundaram J.P., Sutton G., Turner G., Venter J.C.,
RA   White O.R., Whitty B.R., Youngman P., Wolfe K.H., Goldman G.H.,
RA   Wortman J.R., Jiang B., Denning D.W., Nierman W.C.;
RT   "Genomic islands in the pathogenic filamentous fungus Aspergillus
RT   fumigatus.";
RL   PLoS Genet. 4:E1000046-E1000046(2008).
CC   -!- FUNCTION: RNA-binding nucleolar protein required for pre-rRNA
CC       processing. Involved in production of 18S rRNA and assembly of small
CC       ribosomal subunit (By similarity). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus, nucleolus {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the NOP9 family. {ECO:0000305}.
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DR   EMBL; DS027690; EAW21451.1; -; Genomic_DNA.
DR   RefSeq; XP_001263348.1; XM_001263347.1.
DR   AlphaFoldDB; A1D6V7; -.
DR   SMR; A1D6V7; -.
DR   STRING; 36630.CADNFIAP00005687; -.
DR   EnsemblFungi; EAW21451; EAW21451; NFIA_066150.
DR   GeneID; 4589868; -.
DR   KEGG; nfi:NFIA_066150; -.
DR   VEuPathDB; FungiDB:NFIA_066150; -.
DR   eggNOG; KOG2188; Eukaryota.
DR   HOGENOM; CLU_008720_1_1_1; -.
DR   OMA; TPNGSHI; -.
DR   OrthoDB; 238378at2759; -.
DR   Proteomes; UP000006702; Unassembled WGS sequence.
DR   GO; GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR   GO; GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.
DR   Gene3D; 1.25.10.10; -; 2.
DR   InterPro; IPR011989; ARM-like.
DR   InterPro; IPR016024; ARM-type_fold.
DR   InterPro; IPR040000; NOP9.
DR   InterPro; IPR001313; Pumilio_RNA-bd_rpt.
DR   PANTHER; PTHR13102; PTHR13102; 1.
DR   Pfam; PF00806; PUF; 2.
DR   SMART; SM00025; Pumilio; 5.
DR   SUPFAM; SSF48371; SSF48371; 1.
PE   3: Inferred from homology;
KW   Nucleus; Reference proteome; Repeat; Ribosome biogenesis; rRNA processing.
FT   CHAIN           1..699
FT                   /note="Nucleolar protein 9"
FT                   /id="PRO_0000407819"
FT   REPEAT          120..155
FT                   /note="Pumilio 1"
FT   REPEAT          156..191
FT                   /note="Pumilio 2"
FT   REPEAT          361..396
FT                   /note="Pumilio 3"
FT   REPEAT          397..433
FT                   /note="Pumilio 4"
FT   REPEAT          540..580
FT                   /note="Pumilio 5"
FT   REPEAT          582..619
FT                   /note="Pumilio 6"
FT   REGION          1..66
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          492..511
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1..38
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        39..53
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   699 AA;  78158 MW;  2C20E9D229D54886 CRC64;
     MPREKQKRGR RAEDKAKKDA AKRKRDEFPE ESAVKRLKPS AETDTSNNEV TSGADYIPLE
     AEDGGNDVSM NDAPANDMPF YGLLDSEEQE YFSKANEVLE LNQFHDAEER RLFVDSVYRE
     ADGKELKVAC SQSCSRLMEK LISLSDMRQI RRLFNKFIGH FLHLVQHRFA SHCCETLFIN
     AAPGVTEKIS KSKGRKAEVD EEDEPEPELS LAEMFMKVVE ELEGNWGYLL TERFASHTIR
     VLLLVLAGEP VDLSSTDSVV ASRKKERLGI VNTEASEENA VAERRKVPEV FEATLKKVMN
     DMVSGLDNTY LRALATHPVG NPVLQVLVFL ELSHFGKASA KDPNSIIRRL IPDDDFGENA
     ESSTFVRGLL YDPVGSRLLE TIIKSMPGKL FKSLYKNIIR DRIGSLARNT TAGYVVLRTL
     ERLGKDDLQD AMELIIPEIP GLIERSRLIV PKVLIERCLV RGVDTKPLSD ALESAYDKNP
     ARRLEQMLKL EPAASEEDSE EKQKQTGNNQ TAAAEKLHGS LLAQTMLTAS GPVSGLIYSS
     LLAQSAESLL RLAKDPTASR VLQQALTTPT STSQFRRQFT TRFSGHLVEL ALDSSGSHVV
     DALWPATKDL FFVKERMAQE LLKEELSLRD SFVGRAVWRN WSMDLYKRRR GEWASKAKGL
     DSIENGQGER PKSRIDLARA KFAAKAAEES SKAPVAAKT