ID   NOP9_PARBA              Reviewed;         689 AA.
AC   C1H8W8;
DT   03-MAY-2011, integrated into UniProtKB/Swiss-Prot.
DT   26-MAY-2009, sequence version 1.
DT   25-MAY-2022, entry version 56.
DE   RecName: Full=Nucleolar protein 9;
DE   AltName: Full=Pumilio domain-containing protein NOP9;
GN   Name=NOP9; ORFNames=PAAG_07209;
OS   Paracoccidioides lutzii (strain ATCC MYA-826 / Pb01) (Paracoccidioides
OS   brasiliensis).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Onygenales; Onygenales incertae sedis; Paracoccidioides.
OX   NCBI_TaxID=502779;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC MYA-826 / Pb01;
RX   PubMed=22046142; DOI=10.1371/journal.pgen.1002345;
RA   Desjardins C.A., Champion M.D., Holder J.W., Muszewska A., Goldberg J.,
RA   Bailao A.M., Brigido M.M., Ferreira M.E., Garcia A.M., Grynberg M.,
RA   Gujja S., Heiman D.I., Henn M.R., Kodira C.D., Leon-Narvaez H.,
RA   Longo L.V.G., Ma L.-J., Malavazi I., Matsuo A.L., Morais F.V., Pereira M.,
RA   Rodriguez-Brito S., Sakthikumar S., Salem-Izacc S.M., Sykes S.M.,
RA   Teixeira M.M., Vallejo M.C., Walter M.E., Yandava C., Young S., Zeng Q.,
RA   Zucker J., Felipe M.S., Goldman G.H., Haas B.J., McEwen J.G., Nino-Vega G.,
RA   Puccia R., San-Blas G., Soares C.M., Birren B.W., Cuomo C.A.;
RT   "Comparative genomic analysis of human fungal pathogens causing
RT   paracoccidioidomycosis.";
RL   PLoS Genet. 7:E1002345-E1002345(2011).
CC   -!- FUNCTION: RNA-binding nucleolar protein required for pre-rRNA
CC       processing. Involved in production of 18S rRNA and assembly of small
CC       ribosomal subunit (By similarity). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus, nucleolus {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the NOP9 family. {ECO:0000305}.
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DR   EMBL; KN294013; EEH36791.1; -; Genomic_DNA.
DR   RefSeq; XP_002790973.1; XM_002790927.1.
DR   AlphaFoldDB; C1H8W8; -.
DR   SMR; C1H8W8; -.
DR   STRING; 502779.C1H8W8; -.
DR   EnsemblFungi; EEH36791; EEH36791; PAAG_07209.
DR   GeneID; 9094224; -.
DR   KEGG; pbl:PAAG_07209; -.
DR   VEuPathDB; FungiDB:PAAG_07209; -.
DR   eggNOG; KOG2188; Eukaryota.
DR   HOGENOM; CLU_008720_1_1_1; -.
DR   OMA; TPNGSHI; -.
DR   OrthoDB; 238378at2759; -.
DR   Proteomes; UP000002059; Partially assembled WGS sequence.
DR   GO; GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR   GO; GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.
DR   Gene3D; 1.25.10.10; -; 3.
DR   InterPro; IPR011989; ARM-like.
DR   InterPro; IPR016024; ARM-type_fold.
DR   InterPro; IPR040000; NOP9.
DR   InterPro; IPR001313; Pumilio_RNA-bd_rpt.
DR   PANTHER; PTHR13102; PTHR13102; 1.
DR   SMART; SM00025; Pumilio; 6.
DR   SUPFAM; SSF48371; SSF48371; 1.
PE   3: Inferred from homology;
KW   Nucleus; Reference proteome; Repeat; Ribosome biogenesis; rRNA processing.
FT   CHAIN           1..689
FT                   /note="Nucleolar protein 9"
FT                   /id="PRO_0000407821"
FT   REPEAT          108..143
FT                   /note="Pumilio 1"
FT   REPEAT          291..334
FT                   /note="Pumilio 2"
FT   REPEAT          382..419
FT                   /note="Pumilio 3"
FT   REPEAT          524..562
FT                   /note="Pumilio 4"
FT   REPEAT          563..600
FT                   /note="Pumilio 5"
FT   REGION          1..39
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          477..496
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          670..689
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1..26
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        675..689
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   689 AA;  77007 MW;  1C88C22549A0A015 CRC64;
     MPREKQKRGR RAEAKRKRDD VITDPTVLKR QKSSDVSNYP NRSYEQLEIR GDYIPLDEEL
     VDSTGTAFYG LLDIEEQEYF SHASGLLELN QFETEEEKSI FIERVYEEAN GKELKIACSQ
     SCSRLMEKLI SASTVSQIKR LFSKFIGHFL DLVQHRFASH CCECLFIHAA QYVTSEMKKK
     SSKEKENLEE DSTSELQLED LFLKAISELE GNWGYLLTER FASHTIRVLL LVLAGKPLRN
     PSTTTVIASR KKEYLASKVG TQLDPSISEK QAVPTSFNKA LEKMMKDLVT GLDNTYLRAL
     ATHPVGNPVL QVLLSVELSH MGKSKAKDAD SVLRRLVPDE NLQEDGESAT FLKGLFYDPV
     GSRLLETIVQ DAPGKFFKLF YKIIVRERIG SFSRNEIAGH VVVRILERLS KEDLKSAMDL
     ILPEVPPLVE RSRLTVIKAL IERGIVRGVD LGPLAATLLS AYGDDAVSRI NNMLKLQRSN
     KENDGTTSSS NTSSPEQLHG SLLAQAMLKS TGPLCELVQS SLLAVTPETL ISIAQDPVVS
     HVLQDALTLP TSTPQFRRQI TSRLSGKIAE LALHSSGSHV VDALWPATRD LIFVKQRFAE
     ELVVHERALR DSFVGRAVWR NWSMDLYKRK RGSWIAIAKG LEDSAEVNLN TLTNKPKSNI
     DLARARFAAK ANGSKEPANT PSKKIPTTS