NOP9_PARBD
ID NOP9_PARBD Reviewed; 678 AA.
AC C1FYU3;
DT 03-MAY-2011, integrated into UniProtKB/Swiss-Prot.
DT 26-MAY-2009, sequence version 1.
DT 25-MAY-2022, entry version 49.
DE RecName: Full=Nucleolar protein 9;
DE AltName: Full=Pumilio domain-containing protein NOP9;
GN Name=NOP9; ORFNames=PADG_00969;
OS Paracoccidioides brasiliensis (strain Pb18).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Onygenales; Onygenales incertae sedis; Paracoccidioides.
OX NCBI_TaxID=502780;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Pb18;
RX PubMed=22046142; DOI=10.1371/journal.pgen.1002345;
RA Desjardins C.A., Champion M.D., Holder J.W., Muszewska A., Goldberg J.,
RA Bailao A.M., Brigido M.M., Ferreira M.E., Garcia A.M., Grynberg M.,
RA Gujja S., Heiman D.I., Henn M.R., Kodira C.D., Leon-Narvaez H.,
RA Longo L.V.G., Ma L.-J., Malavazi I., Matsuo A.L., Morais F.V., Pereira M.,
RA Rodriguez-Brito S., Sakthikumar S., Salem-Izacc S.M., Sykes S.M.,
RA Teixeira M.M., Vallejo M.C., Walter M.E., Yandava C., Young S., Zeng Q.,
RA Zucker J., Felipe M.S., Goldman G.H., Haas B.J., McEwen J.G., Nino-Vega G.,
RA Puccia R., San-Blas G., Soares C.M., Birren B.W., Cuomo C.A.;
RT "Comparative genomic analysis of human fungal pathogens causing
RT paracoccidioidomycosis.";
RL PLoS Genet. 7:E1002345-E1002345(2011).
CC -!- FUNCTION: RNA-binding nucleolar protein required for pre-rRNA
CC processing. Involved in production of 18S rRNA and assembly of small
CC ribosomal subunit (By similarity). {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Nucleus, nucleolus {ECO:0000250}.
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DR EMBL; KN275957; EEH44680.1; -; Genomic_DNA.
DR RefSeq; XP_010756559.1; XM_010758257.1.
DR AlphaFoldDB; C1FYU3; -.
DR SMR; C1FYU3; -.
DR STRING; 121759.XP_010756559.1; -.
DR EnsemblFungi; EEH44680; EEH44680; PADG_00969.
DR GeneID; 22580727; -.
DR KEGG; pbn:PADG_00969; -.
DR VEuPathDB; FungiDB:PADG_00969; -.
DR eggNOG; KOG2188; Eukaryota.
DR HOGENOM; CLU_008720_1_1_1; -.
DR OMA; TPNGSHI; -.
DR Proteomes; UP000001628; Unassembled WGS sequence.
DR GO; GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
DR GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR GO; GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.
DR Gene3D; 1.25.10.10; -; 3.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR040000; NOP9.
DR InterPro; IPR001313; Pumilio_RNA-bd_rpt.
DR PANTHER; PTHR13102; PTHR13102; 1.
DR SMART; SM00025; Pumilio; 8.
DR SUPFAM; SSF48371; SSF48371; 1.
PE 3: Inferred from homology;
KW Nucleus; Reference proteome; Repeat; Ribosome biogenesis; rRNA processing.
FT CHAIN 1..678
FT /note="Nucleolar protein 9"
FT /id="PRO_0000407822"
FT REPEAT 108..143
FT /note="Pumilio 1"
FT REPEAT 291..334
FT /note="Pumilio 2"
FT REPEAT 382..419
FT /note="Pumilio 3"
FT REPEAT 524..562
FT /note="Pumilio 4"
FT REPEAT 563..600
FT /note="Pumilio 5"
FT REGION 1..24
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 477..496
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 678 AA; 75759 MW; AD7E5CB1E7C5A846 CRC64;
MPRDKQKRGR RAEAKRKRDD VITDPTVLKR QKSSDVCNYP NPSYEQLEIR GDYIPLDEEP
VDYTGTPFYG LLDIEEQEYF SHASGLLELN QFETEEEKSI FIERVYEEAN GKELKIACSQ
SCSRLMEKLI SASTVSQIKR LFSKFIGHFL NLVQHRFASH CCECLFIHAA QHVTSEMKKK
SSKEKENLEE DSTSELQLED LFLKAISELE GNWGYLLTER FASHTIRLLL LVLAGKPLRN
SSTTTVIASR KKEYLASKVG TQLDPSISEK RAVPTSFNKA LEKMMKDLVA GLDNTYLRAL
ATHPVGNPVL QLLLSVELSH MGKSKAKDPD SLLRRLVPDE NLQGDGESAN FLKGLFYDPV
GSRLLETIVQ DAPGKFFRLF YKILVRERIG SFSRNEIAGH VVVRILERLS KDDLKSAMDM
ILPEVAPLVE RSRLTVIKAL IERGIVRGVD LGPLAAALLS AYGDDAVSRI NNMLKLQRSN
QESDGTTSSS NTSSPEQLHG SLLAQAMLKS TGPLSELVQS SLLAVTTETL ISIAQDPVVS
HVLQDALTLP TSTPQFRRQI TSRFSGKIAE LALHSSGSHV VDALWPATKD LLFVKQRFAE
ELVVHERALR DSFVGRAVWR NWSMDLYKRK RGSWIAIAKG LEDSTDINPN ALTHKPKSNI
DLARARFAAK ANGSKAPS