NOP9_PARBP
ID NOP9_PARBP Reviewed; 678 AA.
AC C0S4C4;
DT 03-MAY-2011, integrated into UniProtKB/Swiss-Prot.
DT 05-MAY-2009, sequence version 1.
DT 25-MAY-2022, entry version 43.
DE RecName: Full=Nucleolar protein 9;
DE AltName: Full=Pumilio domain-containing protein NOP9;
GN Name=NOP9; ORFNames=PABG_02538;
OS Paracoccidioides brasiliensis (strain Pb03).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Onygenales; Onygenales incertae sedis; Paracoccidioides.
OX NCBI_TaxID=482561;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Pb03;
RX PubMed=22046142; DOI=10.1371/journal.pgen.1002345;
RA Desjardins C.A., Champion M.D., Holder J.W., Muszewska A., Goldberg J.,
RA Bailao A.M., Brigido M.M., Ferreira M.E., Garcia A.M., Grynberg M.,
RA Gujja S., Heiman D.I., Henn M.R., Kodira C.D., Leon-Narvaez H.,
RA Longo L.V.G., Ma L.-J., Malavazi I., Matsuo A.L., Morais F.V., Pereira M.,
RA Rodriguez-Brito S., Sakthikumar S., Salem-Izacc S.M., Sykes S.M.,
RA Teixeira M.M., Vallejo M.C., Walter M.E., Yandava C., Young S., Zeng Q.,
RA Zucker J., Felipe M.S., Goldman G.H., Haas B.J., McEwen J.G., Nino-Vega G.,
RA Puccia R., San-Blas G., Soares C.M., Birren B.W., Cuomo C.A.;
RT "Comparative genomic analysis of human fungal pathogens causing
RT paracoccidioidomycosis.";
RL PLoS Genet. 7:E1002345-E1002345(2011).
CC -!- FUNCTION: RNA-binding nucleolar protein required for pre-rRNA
CC processing. Involved in production of 18S rRNA and assembly of small
CC ribosomal subunit (By similarity). {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Nucleus, nucleolus {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the NOP9 family. {ECO:0000305}.
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DR EMBL; KN305533; EEH20279.1; -; Genomic_DNA.
DR AlphaFoldDB; C0S4C4; -.
DR SMR; C0S4C4; -.
DR EnsemblFungi; EEH20279; EEH20279; PABG_02538.
DR VEuPathDB; FungiDB:PABG_02538; -.
DR HOGENOM; CLU_008720_1_1_1; -.
DR InParanoid; C0S4C4; -.
DR Proteomes; UP000002740; Unassembled WGS sequence.
DR GO; GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
DR GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR GO; GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.
DR Gene3D; 1.25.10.10; -; 2.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR040000; NOP9.
DR InterPro; IPR001313; Pumilio_RNA-bd_rpt.
DR PANTHER; PTHR13102; PTHR13102; 1.
DR SMART; SM00025; Pumilio; 8.
DR SUPFAM; SSF48371; SSF48371; 1.
PE 3: Inferred from homology;
KW Nucleus; Repeat; Ribosome biogenesis; rRNA processing.
FT CHAIN 1..678
FT /note="Nucleolar protein 9"
FT /id="PRO_0000407823"
FT REPEAT 108..143
FT /note="Pumilio 1"
FT REPEAT 291..334
FT /note="Pumilio 2"
FT REPEAT 382..419
FT /note="Pumilio 3"
FT REPEAT 524..562
FT /note="Pumilio 4"
FT REPEAT 563..600
FT /note="Pumilio 5"
FT REGION 1..24
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 477..496
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 678 AA; 75804 MW; 537906EAD8D5DD82 CRC64;
MPRDKQKRGR RAEAKRKRDD VITDPTVLKR QKSSDVCNYP NPSYEQLEIR GDYIPLDEEP
VDYTGTPFYG LLDIEEQEYF SHASGLLELN QFETEEEKSI FIERVYEEAN GKELKIACSQ
SCSRLMEKLI SASTVSQIKR LFSKFIGHFL NLVQHRFASH CCECLFIHAA QYVTSEMKKK
SSKEKENLEE DSTSELQLED LFLKAISELE GNWGYLLTER FASHTIRLLL LVLAGKPLRN
PSTTTVIASR KKENLASKVG TQLDPSISEK RAVPTSFNKA LEKMMKDLVA GLDNTYLRAL
ATHPVGNPVL QLLLSVELSH MGKSKAKDPD SLLRRLVPDE NLQGDGESAK FLKGLFYDPV
GSRLLETIVQ DAPGKFFKLF YKILVRERIG SFSRNEIAGH VVVRILERLS KDDLKSAMDM
ILPEVAPLVE RSRLTVIKAL IERGIVRGVD LGPLAAALLS AYGDDAVSRI NNMLKLQRSN
KESDGTTSSS NTSSPEQLHG SLLAQAMLKS TGPLSELVQS SLLAVTTETL ISIAQDPVVS
HVLQDALTLP TSTPQFRRQI TSRFSGKIAE LALHSSGSHV VDALWPATKD LLFVKQRFAE
ELVVHERALR DSFVGRAVWR NWSMDLYKRK RGSWIAIAKG LEDSTEINPN ALTHKPKSNI
DLARARFAAK ANGSKEPS