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NOP9_PARBP
ID   NOP9_PARBP              Reviewed;         678 AA.
AC   C0S4C4;
DT   03-MAY-2011, integrated into UniProtKB/Swiss-Prot.
DT   05-MAY-2009, sequence version 1.
DT   25-MAY-2022, entry version 43.
DE   RecName: Full=Nucleolar protein 9;
DE   AltName: Full=Pumilio domain-containing protein NOP9;
GN   Name=NOP9; ORFNames=PABG_02538;
OS   Paracoccidioides brasiliensis (strain Pb03).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Onygenales; Onygenales incertae sedis; Paracoccidioides.
OX   NCBI_TaxID=482561;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Pb03;
RX   PubMed=22046142; DOI=10.1371/journal.pgen.1002345;
RA   Desjardins C.A., Champion M.D., Holder J.W., Muszewska A., Goldberg J.,
RA   Bailao A.M., Brigido M.M., Ferreira M.E., Garcia A.M., Grynberg M.,
RA   Gujja S., Heiman D.I., Henn M.R., Kodira C.D., Leon-Narvaez H.,
RA   Longo L.V.G., Ma L.-J., Malavazi I., Matsuo A.L., Morais F.V., Pereira M.,
RA   Rodriguez-Brito S., Sakthikumar S., Salem-Izacc S.M., Sykes S.M.,
RA   Teixeira M.M., Vallejo M.C., Walter M.E., Yandava C., Young S., Zeng Q.,
RA   Zucker J., Felipe M.S., Goldman G.H., Haas B.J., McEwen J.G., Nino-Vega G.,
RA   Puccia R., San-Blas G., Soares C.M., Birren B.W., Cuomo C.A.;
RT   "Comparative genomic analysis of human fungal pathogens causing
RT   paracoccidioidomycosis.";
RL   PLoS Genet. 7:E1002345-E1002345(2011).
CC   -!- FUNCTION: RNA-binding nucleolar protein required for pre-rRNA
CC       processing. Involved in production of 18S rRNA and assembly of small
CC       ribosomal subunit (By similarity). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus, nucleolus {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the NOP9 family. {ECO:0000305}.
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DR   EMBL; KN305533; EEH20279.1; -; Genomic_DNA.
DR   AlphaFoldDB; C0S4C4; -.
DR   SMR; C0S4C4; -.
DR   EnsemblFungi; EEH20279; EEH20279; PABG_02538.
DR   VEuPathDB; FungiDB:PABG_02538; -.
DR   HOGENOM; CLU_008720_1_1_1; -.
DR   InParanoid; C0S4C4; -.
DR   Proteomes; UP000002740; Unassembled WGS sequence.
DR   GO; GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR   GO; GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.
DR   Gene3D; 1.25.10.10; -; 2.
DR   InterPro; IPR011989; ARM-like.
DR   InterPro; IPR016024; ARM-type_fold.
DR   InterPro; IPR040000; NOP9.
DR   InterPro; IPR001313; Pumilio_RNA-bd_rpt.
DR   PANTHER; PTHR13102; PTHR13102; 1.
DR   SMART; SM00025; Pumilio; 8.
DR   SUPFAM; SSF48371; SSF48371; 1.
PE   3: Inferred from homology;
KW   Nucleus; Repeat; Ribosome biogenesis; rRNA processing.
FT   CHAIN           1..678
FT                   /note="Nucleolar protein 9"
FT                   /id="PRO_0000407823"
FT   REPEAT          108..143
FT                   /note="Pumilio 1"
FT   REPEAT          291..334
FT                   /note="Pumilio 2"
FT   REPEAT          382..419
FT                   /note="Pumilio 3"
FT   REPEAT          524..562
FT                   /note="Pumilio 4"
FT   REPEAT          563..600
FT                   /note="Pumilio 5"
FT   REGION          1..24
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          477..496
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   678 AA;  75804 MW;  537906EAD8D5DD82 CRC64;
     MPRDKQKRGR RAEAKRKRDD VITDPTVLKR QKSSDVCNYP NPSYEQLEIR GDYIPLDEEP
     VDYTGTPFYG LLDIEEQEYF SHASGLLELN QFETEEEKSI FIERVYEEAN GKELKIACSQ
     SCSRLMEKLI SASTVSQIKR LFSKFIGHFL NLVQHRFASH CCECLFIHAA QYVTSEMKKK
     SSKEKENLEE DSTSELQLED LFLKAISELE GNWGYLLTER FASHTIRLLL LVLAGKPLRN
     PSTTTVIASR KKENLASKVG TQLDPSISEK RAVPTSFNKA LEKMMKDLVA GLDNTYLRAL
     ATHPVGNPVL QLLLSVELSH MGKSKAKDPD SLLRRLVPDE NLQGDGESAK FLKGLFYDPV
     GSRLLETIVQ DAPGKFFKLF YKILVRERIG SFSRNEIAGH VVVRILERLS KDDLKSAMDM
     ILPEVAPLVE RSRLTVIKAL IERGIVRGVD LGPLAAALLS AYGDDAVSRI NNMLKLQRSN
     KESDGTTSSS NTSSPEQLHG SLLAQAMLKS TGPLSELVQS SLLAVTTETL ISIAQDPVVS
     HVLQDALTLP TSTPQFRRQI TSRFSGKIAE LALHSSGSHV VDALWPATKD LLFVKQRFAE
     ELVVHERALR DSFVGRAVWR NWSMDLYKRK RGSWIAIAKG LEDSTEINPN ALTHKPKSNI
     DLARARFAAK ANGSKEPS
 
 
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