ID   NOP9_PENRW              Reviewed;         722 AA.
AC   B6H3T4;
DT   03-MAY-2011, integrated into UniProtKB/Swiss-Prot.
DT   16-DEC-2008, sequence version 1.
DT   03-AUG-2022, entry version 66.
DE   RecName: Full=Nucleolar protein 9;
DE   AltName: Full=Pumilio domain-containing protein nop9;
GN   Name=nop9; ORFNames=Pc13g09340;
OS   Penicillium rubens (strain ATCC 28089 / DSM 1075 / NRRL 1951 / Wisconsin
OS   54-1255) (Penicillium chrysogenum).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Eurotiales; Aspergillaceae; Penicillium;
OC   Penicillium chrysogenum species complex.
OX   NCBI_TaxID=500485;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 28089 / DSM 1075 / NRRL 1951 / Wisconsin 54-1255;
RX   PubMed=18820685; DOI=10.1038/nbt.1498;
RA   van den Berg M.A., Albang R., Albermann K., Badger J.H., Daran J.-M.,
RA   Driessen A.J.M., Garcia-Estrada C., Fedorova N.D., Harris D.M.,
RA   Heijne W.H.M., Joardar V.S., Kiel J.A.K.W., Kovalchuk A., Martin J.F.,
RA   Nierman W.C., Nijland J.G., Pronk J.T., Roubos J.A., van der Klei I.J.,
RA   van Peij N.N.M.E., Veenhuis M., von Doehren H., Wagner C., Wortman J.R.,
RA   Bovenberg R.A.L.;
RT   "Genome sequencing and analysis of the filamentous fungus Penicillium
RT   chrysogenum.";
RL   Nat. Biotechnol. 26:1161-1168(2008).
CC   -!- FUNCTION: RNA-binding nucleolar protein required for pre-rRNA
CC       processing. Involved in production of 18S rRNA and assembly of small
CC       ribosomal subunit (By similarity). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus, nucleolus {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the NOP9 family. {ECO:0000305}.
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DR   EMBL; AM920428; CAP92003.1; -; Genomic_DNA.
DR   RefSeq; XP_002559358.1; XM_002559312.1.
DR   AlphaFoldDB; B6H3T4; -.
DR   SMR; B6H3T4; -.
DR   STRING; 1108849.XP_002559358.1; -.
DR   EnsemblFungi; CAP92003; CAP92003; PCH_Pc13g09340.
DR   GeneID; 8316061; -.
DR   KEGG; pcs:Pc13g09340; -.
DR   VEuPathDB; FungiDB:PCH_Pc13g09340; -.
DR   eggNOG; KOG2188; Eukaryota.
DR   HOGENOM; CLU_008720_1_1_1; -.
DR   OMA; TPNGSHI; -.
DR   OrthoDB; 238378at2759; -.
DR   BioCyc; PCHR:PC13G09340-MON; -.
DR   Proteomes; UP000000724; Contig Pc00c13.
DR   GO; GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR   GO; GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.
DR   Gene3D; 1.25.10.10; -; 2.
DR   InterPro; IPR011989; ARM-like.
DR   InterPro; IPR016024; ARM-type_fold.
DR   InterPro; IPR040000; NOP9.
DR   InterPro; IPR001313; Pumilio_RNA-bd_rpt.
DR   PANTHER; PTHR13102; PTHR13102; 1.
DR   SMART; SM00025; Pumilio; 5.
DR   SUPFAM; SSF48371; SSF48371; 2.
PE   3: Inferred from homology;
KW   Nucleus; Reference proteome; Repeat; Ribosome biogenesis; rRNA processing.
FT   CHAIN           1..722
FT                   /note="Nucleolar protein 9"
FT                   /id="PRO_0000407824"
FT   REPEAT          123..158
FT                   /note="Pumilio 1"
FT   REPEAT          363..398
FT                   /note="Pumilio 2"
FT   REPEAT          400..435
FT                   /note="Pumilio 3"
FT   REPEAT          556..597
FT                   /note="Pumilio 4"
FT   REPEAT          598..635
FT                   /note="Pumilio 5"
FT   REGION          1..54
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          496..529
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          676..722
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1..50
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        501..522
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        676..701
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   722 AA;  81434 MW;  481D1EF196C02FFE CRC64;
     MPREQQKRGR RAEKKSQKED SKRKFEETSE DPVAKRIKPS ADDHETNEAN DNIQLLENED
     YIPLEQGEQQ EGEQPDLDGD MPFYGLLDEE ESEYFQRANE MLELNQFQDA EERSLFVDSV
     YSEANGKELK IACSQGCSRL MEKLISMSDA RQLRRIFSKF IGHFLHLVQH RFASHCCETL
     FIHAAPAVMQ KTKSQPKRSD EEGEEEPELS LADMFMAVIE ELKENWGYLL TERFASHTIR
     VLLLVLAGEP VDVTSNESFV ASRKKERIEI PTIQGEEKAG KSKAEKHTVP ETFEPALKKI
     MTDMVAGLDD VYLRALATHP VGNPVLQVLL FLELSHFGKS SAKDPKSTIR RLVPDESFEE
     GSESAVFISG LLYDAVGSRL LETMVRYLPG KSFKNLYRNN LGDRIGSLSR NSTAGYVVLR
     MLERLGKDDL KIAMANINPE VPGLIERSRL IVPKMLIERC MVRGVDTKPL AEALEGAYSK
     DPAVRLQQML KFNISENTAP QSEDHDMEED NDGKDRKPRG PPPVSAAEKA EKLHASLLVQ
     AMLTVPGPMS QLVYTSLLAQ SSETIVQLAQ EPTSSRVLQQ ALTSTTSTPQ IRRQLTTRFQ
     GYLTPLALSS SGSHVVDALW SATKDIFFVK ERMAQELEQH EQELRDSFVG RAVWRNWSMD
     LFKRRRRDWT HKAKGFEERT EGNEGAERPK SKIEQARARY AAAKEAADAG ATGANQTTVA
     SR