ID   NOP9_PICST              Reviewed;         711 AA.
AC   A3LXG0;
DT   03-MAY-2011, integrated into UniProtKB/Swiss-Prot.
DT   03-APR-2007, sequence version 1.
DT   25-MAY-2022, entry version 73.
DE   RecName: Full=Nucleolar protein 9;
DE   AltName: Full=Pumilio domain-containing protein NOP9;
GN   Name=NOP9; ORFNames=PICST_32802;
OS   Scheffersomyces stipitis (strain ATCC 58785 / CBS 6054 / NBRC 10063 / NRRL
OS   Y-11545) (Yeast) (Pichia stipitis).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Debaryomycetaceae; Scheffersomyces.
OX   NCBI_TaxID=322104;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 58785 / CBS 6054 / NBRC 10063 / NRRL Y-11545;
RX   PubMed=17334359; DOI=10.1038/nbt1290;
RA   Jeffries T.W., Grigoriev I.V., Grimwood J., Laplaza J.M., Aerts A.,
RA   Salamov A., Schmutz J., Lindquist E., Dehal P., Shapiro H., Jin Y.-S.,
RA   Passoth V., Richardson P.M.;
RT   "Genome sequence of the lignocellulose-bioconverting and xylose-fermenting
RT   yeast Pichia stipitis.";
RL   Nat. Biotechnol. 25:319-326(2007).
CC   -!- FUNCTION: RNA-binding nucleolar protein required for pre-rRNA
CC       processing. Involved in production of 18S rRNA and assembly of small
CC       ribosomal subunit (By similarity). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus, nucleolus {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the NOP9 family. {ECO:0000305}.
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DR   EMBL; CP000500; ABN67450.1; -; Genomic_DNA.
DR   RefSeq; XP_001385479.1; XM_001385442.1.
DR   AlphaFoldDB; A3LXG0; -.
DR   SMR; A3LXG0; -.
DR   STRING; 4924.XP_001385479.1; -.
DR   EnsemblFungi; ABN67450; ABN67450; PICST_32802.
DR   GeneID; 4840357; -.
DR   KEGG; pic:PICST_32802; -.
DR   eggNOG; KOG2188; Eukaryota.
DR   HOGENOM; CLU_008720_1_1_1; -.
DR   InParanoid; A3LXG0; -.
DR   OMA; IWDELGS; -.
DR   OrthoDB; 238378at2759; -.
DR   Proteomes; UP000002258; Chromosome 6.
DR   GO; GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR   GO; GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.
DR   Gene3D; 1.25.10.10; -; 2.
DR   InterPro; IPR011989; ARM-like.
DR   InterPro; IPR016024; ARM-type_fold.
DR   InterPro; IPR040000; NOP9.
DR   InterPro; IPR001313; Pumilio_RNA-bd_rpt.
DR   PANTHER; PTHR13102; PTHR13102; 1.
DR   SMART; SM00025; Pumilio; 8.
DR   SUPFAM; SSF48371; SSF48371; 1.
DR   PROSITE; PS50302; PUM; 5.
PE   3: Inferred from homology;
KW   Nucleus; Reference proteome; Repeat; Ribosome biogenesis; rRNA processing.
FT   CHAIN           1..711
FT                   /note="Nucleolar protein 9"
FT                   /id="PRO_0000407829"
FT   REPEAT          91..126
FT                   /note="Pumilio 1"
FT   REPEAT          127..162
FT                   /note="Pumilio 2"
FT   REPEAT          194..230
FT                   /note="Pumilio 3"
FT   REPEAT          279..314
FT                   /note="Pumilio 4"
FT   REPEAT          328..365
FT                   /note="Pumilio 5"
FT   REPEAT          519..556
FT                   /note="Pumilio 6"
FT   REPEAT          563..601
FT                   /note="Pumilio 7"
FT   REGION          1..43
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          161..180
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          676..711
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1..37
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        676..704
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   711 AA;  82520 MW;  A44AA3B865461EE6 CRC64;
     MAKTKSRGRR VEKSADKLEK KAQSLFEDTK STGEEGGDDS NEIDASLKSP FFGLVDSNEL
     DYFKQAESTL NVNAFDSDED REGFIRSVLE EARGKELKLV TNQICSKLME RLILFASDRQ
     LKNIFGQFSG HFVALAHHKY SSHVLETLLV RSAALIEKEL IHDDSSQNEE EREEQEEGEV
     TDPMEGLFIK MVDEFKPHLQ GMLEHQYSSH VLRLLILILA GKELPSTTTS NSTLRSKKSK
     IARKMIEIKD NQDFNKSFQT PSSFKIQLRE LCNSVSNNQN SKRMRELAIH KIASPVLQLL
     IQVEGLVDRD RTFWHLIFLK DSEDKNSQEE AFVEYLLSDS VGSHFLEATI KNDGARIKYI
     ERLYKLYMED RILKLAKRST TGVYIIQALL FKLKPVDVEH ILDEIIPELS NLISISENQN
     LDLGQRLIDA SISRGNYRRD EIIEQLFLKF APNYNVQDPQ LKTTSEFIEN VLQLTGSTLG
     NTRDDWPTAE ERRRSFFLEK LMEYDYKFVI CVWYNFLALP VERFIQMCFH GVFSHIVERA
     LVVIPSSEGE PKPVLILRKR VLNLFKDQIV NMSCNSYGSH IVDALWNFSV LLPMYKDRIG
     TELQGDSHKV KESTYGRLVW KNWSMELFVR KKYDWKSLIK QQEQAYYGVN DENGTTSRVK
     KPIELKMEKL AEERRLREEA AAKSESGYKR RHEDDNEDDY AKKQKLRGRR R