NOP9_SCHPO
ID NOP9_SCHPO Reviewed; 655 AA.
AC Q92347;
DT 01-NOV-1997, integrated into UniProtKB/Swiss-Prot.
DT 01-FEB-1997, sequence version 1.
DT 03-AUG-2022, entry version 124.
DE RecName: Full=Nucleolar protein 9;
DE AltName: Full=Pumilio domain-containing protein nop9;
GN Name=nop9; ORFNames=SPAC6G9.02c;
OS Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae;
OC Schizosaccharomyces.
OX NCBI_TaxID=284812;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=972 / ATCC 24843;
RX PubMed=11859360; DOI=10.1038/nature724;
RA Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A.,
RA Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S.,
RA Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.,
RA Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S.,
RA Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S.,
RA Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D.,
RA Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P.,
RA Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K.,
RA O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M.,
RA Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N.,
RA Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A.,
RA Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R.,
RA Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M.,
RA Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A.,
RA Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A.,
RA Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H.,
RA Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S.,
RA Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C.,
RA Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A.,
RA Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M.,
RA del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S.,
RA Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R.,
RA Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G.,
RA Nurse P.;
RT "The genome sequence of Schizosaccharomyces pombe.";
RL Nature 415:871-880(2002).
CC -!- FUNCTION: RNA-binding nucleolar protein required for pre-rRNA
CC processing. Involved in production of 18S rRNA and assembly of small
CC ribosomal subunit (By similarity). {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Nucleus, nucleolus {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the NOP9 family. {ECO:0000305}.
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DR EMBL; CU329670; CAB03604.1; -; Genomic_DNA.
DR PIR; T39064; T39064.
DR RefSeq; NP_594111.1; NM_001019535.2.
DR AlphaFoldDB; Q92347; -.
DR SMR; Q92347; -.
DR BioGRID; 278525; 2.
DR STRING; 4896.SPAC6G9.02c.1; -.
DR iPTMnet; Q92347; -.
DR MaxQB; Q92347; -.
DR PaxDb; Q92347; -.
DR PRIDE; Q92347; -.
DR EnsemblFungi; SPAC6G9.02c.1; SPAC6G9.02c.1:pep; SPAC6G9.02c.
DR GeneID; 2542044; -.
DR KEGG; spo:SPAC6G9.02c; -.
DR PomBase; SPAC6G9.02c; nop9.
DR VEuPathDB; FungiDB:SPAC6G9.02c; -.
DR eggNOG; KOG2188; Eukaryota.
DR HOGENOM; CLU_008720_0_0_1; -.
DR InParanoid; Q92347; -.
DR OMA; TPNGSHI; -.
DR PhylomeDB; Q92347; -.
DR PRO; PR:Q92347; -.
DR Proteomes; UP000002485; Chromosome I.
DR GO; GO:0030686; C:90S preribosome; IBA:GO_Central.
DR GO; GO:0005730; C:nucleolus; HDA:PomBase.
DR GO; GO:0005634; C:nucleus; HDA:PomBase.
DR GO; GO:0030688; C:preribosome, small subunit precursor; ISO:PomBase.
DR GO; GO:0003723; F:RNA binding; ISO:PomBase.
DR GO; GO:0000480; P:endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); IBA:GO_Central.
DR GO; GO:0000447; P:endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); IBA:GO_Central.
DR GO; GO:0000472; P:endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA); IBA:GO_Central.
DR GO; GO:0000056; P:ribosomal small subunit export from nucleus; IBA:GO_Central.
DR Gene3D; 1.25.10.10; -; 3.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR040000; NOP9.
DR InterPro; IPR001313; Pumilio_RNA-bd_rpt.
DR PANTHER; PTHR13102; PTHR13102; 1.
DR SMART; SM00025; Pumilio; 7.
DR SUPFAM; SSF48371; SSF48371; 1.
PE 3: Inferred from homology;
KW Nucleus; Reference proteome; Repeat; Ribosome biogenesis; rRNA processing.
FT CHAIN 1..655
FT /note="Nucleolar protein 9"
FT /id="PRO_0000075937"
FT REPEAT 96..131
FT /note="Pumilio 1"
FT REPEAT 132..170
FT /note="Pumilio 2"
FT REPEAT 260..303
FT /note="Pumilio 3"
FT REPEAT 314..348
FT /note="Pumilio 4"
FT REPEAT 349..385
FT /note="Pumilio 5"
FT REPEAT 490..528
FT /note="Pumilio 6"
FT REPEAT 529..566
FT /note="Pumilio 7"
FT REGION 1..41
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 612..655
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 637..655
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 655 AA; 75440 MW; 45E6C4491692DA42 CRC64;
MPKKRKTRGK KHSAKQKEEE VNSVVSPGIA KNDEGAGNDE GAYQVNRYTN EPVQPFFGAL
DPEEEKYFQQ AEQAFANHFT RENEDTRFFV DSIYREVQGK ELIVCNNVFG SKVLEKLFPL
STSRQIKSFF SALNGHYVEL IQTTFGSYAF EKLLSHMAAI LNLETQGVTE DQDDVLEGEN
ENVFMTAETL LMYMYNEIRP EVSMLMSHKL AVHVLGKIFL LLDGYRFVYH DGNRTTMESI
SVPESFPQFA YSIIDSATDN LDTPELRAYC VDKYASQIMR AFIRIDFERS KKTKKKHDPR
LVSKLLLSNE YDLKELPFME TLLKDETGSR ILEVIVENMS ASHLLRFYAV FEGRFYRLCV
HPIANFIMQR YIRRLGRKEI GSVIDELKKN TDNIIRKSFL PVLRTLLEKS NHLHCYQDDI
FSMIQTSVTN SGKDANIIPC LLRSKHKRDK ANPENKERKL VNNLLGAQLL EEMLHCEKQH
IQLLLDSVLD LSKEQILEYC LETVSSHLIE GILDLSDLNP VFLKKFLNIL SGSFATLAVS
APGSHIVDKA WKATRALPLY RTRIVRELAE GGDDVKFDFY GKKVCSNWKV ELFRRAPDEW
YRFMKQDEPS KRVHERARQY GRIVSGSSAN TQPLGEKRST ENDEELESGP KRVKV
