ID   NOP9_VANPO              Reviewed;         677 AA.
AC   A7TH34;
DT   03-MAY-2011, integrated into UniProtKB/Swiss-Prot.
DT   02-OCT-2007, sequence version 1.
DT   25-MAY-2022, entry version 62.
DE   RecName: Full=Nucleolar protein 9;
DE   AltName: Full=Pumilio domain-containing protein NOP9;
GN   Name=NOP9; ORFNames=Kpol_1032p83;
OS   Vanderwaltozyma polyspora (strain ATCC 22028 / DSM 70294 / BCRC 21397 / CBS
OS   2163 / NBRC 10782 / NRRL Y-8283 / UCD 57-17) (Kluyveromyces polysporus).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Vanderwaltozyma.
OX   NCBI_TaxID=436907;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 22028 / DSM 70294 / BCRC 21397 / CBS 2163 / NBRC 10782 / NRRL
RC   Y-8283 / UCD 57-17;
RX   PubMed=17494770; DOI=10.1073/pnas.0608218104;
RA   Scannell D.R., Frank A.C., Conant G.C., Byrne K.P., Woolfit M., Wolfe K.H.;
RT   "Independent sorting-out of thousands of duplicated gene pairs in two yeast
RT   species descended from a whole-genome duplication.";
RL   Proc. Natl. Acad. Sci. U.S.A. 104:8397-8402(2007).
CC   -!- FUNCTION: RNA-binding nucleolar protein required for pre-rRNA
CC       processing. Involved in production of 18S rRNA and assembly of small
CC       ribosomal subunit (By similarity). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus, nucleolus {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the NOP9 family. {ECO:0000305}.
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DR   EMBL; DS480389; EDO18486.1; -; Genomic_DNA.
DR   RefSeq; XP_001646344.1; XM_001646294.1.
DR   AlphaFoldDB; A7TH34; -.
DR   SMR; A7TH34; -.
DR   STRING; 436907.A7TH34; -.
DR   EnsemblFungi; EDO18486; EDO18486; Kpol_1032p83.
DR   GeneID; 5546774; -.
DR   KEGG; vpo:Kpol_1032p83; -.
DR   eggNOG; KOG2188; Eukaryota.
DR   HOGENOM; CLU_008720_1_1_1; -.
DR   InParanoid; A7TH34; -.
DR   OMA; TPNGSHI; -.
DR   OrthoDB; 238378at2759; -.
DR   PhylomeDB; A7TH34; -.
DR   Proteomes; UP000000267; Unassembled WGS sequence.
DR   GO; GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR   GO; GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.
DR   Gene3D; 1.25.10.10; -; 3.
DR   InterPro; IPR011989; ARM-like.
DR   InterPro; IPR016024; ARM-type_fold.
DR   InterPro; IPR040000; NOP9.
DR   InterPro; IPR001313; Pumilio_RNA-bd_rpt.
DR   PANTHER; PTHR13102; PTHR13102; 1.
DR   Pfam; PF00806; PUF; 2.
DR   SMART; SM00025; Pumilio; 8.
DR   SUPFAM; SSF48371; SSF48371; 1.
PE   3: Inferred from homology;
KW   Nucleus; Reference proteome; Repeat; Ribosome biogenesis; rRNA processing.
FT   CHAIN           1..677
FT                   /note="Nucleolar protein 9"
FT                   /id="PRO_0000407836"
FT   REPEAT          94..129
FT                   /note="Pumilio 1"
FT   REPEAT          130..165
FT                   /note="Pumilio 2"
FT   REPEAT          193..228
FT                   /note="Pumilio 3"
FT   REPEAT          287..331
FT                   /note="Pumilio 4"
FT   REPEAT          339..374
FT                   /note="Pumilio 5"
FT   REPEAT          375..412
FT                   /note="Pumilio 6"
FT   REPEAT          516..553
FT                   /note="Pumilio 7"
FT   REPEAT          554..592
FT                   /note="Pumilio 8"
FT   REGION          1..50
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          639..677
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        11..40
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        643..677
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   677 AA;  79001 MW;  C8C813FC56C5D371 CRC64;
     MAKPRGRKLL KKQQKDQFEP SNDVEKFEDD RDHQENVYQG DAADSEKSSD PQMFFGVLDR
     EELEYFKQIE STLAMDTFES SEEKSQMVTN VLQEAKGKEL KLVTSQICSK LMERIILECD
     DMQLKSVFKA FNGFFYNLSC HKYASHVLET LFVRSAALLE KELLTPTFDN ETSNEDGEVF
     GTMENMFLFM LNELKPHLKS MVSHQYASHS LRLLILILSS KMLPSSTKNN STLRSKKSKI
     ARKMIDIKDN DDFNKVYQTP ESFKLELREM LTSLYKQYTH NADSRSDISP TDITKFRELC
     VDKVASPVIQ LIIQIEGIFD RDRAYWRLVF NTNDEKDPKE EAFVEYLLSD SVGSHFLENV
     IASARLKYVE RLYHLYMKDR IVKLAKRDTT GAFVVQAFLK HMKEKDVKQI LDDIIPELSI
     LLNSNMDFGT SIINASNRLG CYLKDEVVNQ LIKKYYPEES ENKNILESCL LLSSSTLGNT
     RDDWPTADER RRSIFLEQLV NYDDQFLTIT IDSMLNLPEE RFLQMCYHGV FSHVVESVLQ
     TKRVDTIKRR LLLNVLSKDI VNMSCNAYGS HIADKLWEFT AKLTVYKERI AQALVDETEK
     VKNSTYGRQV WKNWSLELYV RKRWDWKKLI KEQEHELFPN AVKPQPKNQQ FKNNGNDNKR
     SSDSNYSSSS NFKKQRR