NOP9_YARLI
ID NOP9_YARLI Reviewed; 724 AA.
AC Q6C9H2;
DT 03-MAY-2011, integrated into UniProtKB/Swiss-Prot.
DT 16-AUG-2004, sequence version 1.
DT 25-MAY-2022, entry version 86.
DE RecName: Full=Nucleolar protein 9;
DE AltName: Full=Pumilio domain-containing protein NOP9;
GN Name=NOP9; OrderedLocusNames=YALI0D11242g;
OS Yarrowia lipolytica (strain CLIB 122 / E 150) (Yeast) (Candida lipolytica).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Dipodascaceae; Yarrowia.
OX NCBI_TaxID=284591;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CLIB 122 / E 150;
RX PubMed=15229592; DOI=10.1038/nature02579;
RA Dujon B., Sherman D., Fischer G., Durrens P., Casaregola S., Lafontaine I.,
RA de Montigny J., Marck C., Neuveglise C., Talla E., Goffard N., Frangeul L.,
RA Aigle M., Anthouard V., Babour A., Barbe V., Barnay S., Blanchin S.,
RA Beckerich J.-M., Beyne E., Bleykasten C., Boisrame A., Boyer J.,
RA Cattolico L., Confanioleri F., de Daruvar A., Despons L., Fabre E.,
RA Fairhead C., Ferry-Dumazet H., Groppi A., Hantraye F., Hennequin C.,
RA Jauniaux N., Joyet P., Kachouri R., Kerrest A., Koszul R., Lemaire M.,
RA Lesur I., Ma L., Muller H., Nicaud J.-M., Nikolski M., Oztas S.,
RA Ozier-Kalogeropoulos O., Pellenz S., Potier S., Richard G.-F.,
RA Straub M.-L., Suleau A., Swennen D., Tekaia F., Wesolowski-Louvel M.,
RA Westhof E., Wirth B., Zeniou-Meyer M., Zivanovic Y., Bolotin-Fukuhara M.,
RA Thierry A., Bouchier C., Caudron B., Scarpelli C., Gaillardin C.,
RA Weissenbach J., Wincker P., Souciet J.-L.;
RT "Genome evolution in yeasts.";
RL Nature 430:35-44(2004).
CC -!- FUNCTION: RNA-binding nucleolar protein required for pre-rRNA
CC processing. Involved in production of 18S rRNA and assembly of small
CC ribosomal subunit (By similarity). {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Nucleus, nucleolus {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the NOP9 family. {ECO:0000305}.
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DR EMBL; CR382130; CAG80878.1; -; Genomic_DNA.
DR RefSeq; XP_502690.1; XM_502690.1.
DR AlphaFoldDB; Q6C9H2; -.
DR SMR; Q6C9H2; -.
DR STRING; 4952.CAG80878; -.
DR EnsemblFungi; CAG80878; CAG80878; YALI0_D11242g.
DR GeneID; 2910732; -.
DR KEGG; yli:YALI0D11242g; -.
DR VEuPathDB; FungiDB:YALI0_D11242g; -.
DR HOGENOM; CLU_008720_1_1_1; -.
DR InParanoid; Q6C9H2; -.
DR OMA; TPNGSHI; -.
DR Proteomes; UP000001300; Chromosome D.
DR GO; GO:0030686; C:90S preribosome; IBA:GO_Central.
DR GO; GO:0005730; C:nucleolus; IBA:GO_Central.
DR GO; GO:0030688; C:preribosome, small subunit precursor; IBA:GO_Central.
DR GO; GO:0032040; C:small-subunit processome; IEA:EnsemblFungi.
DR GO; GO:0003723; F:RNA binding; IBA:GO_Central.
DR GO; GO:0000480; P:endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); IBA:GO_Central.
DR GO; GO:0000447; P:endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); IBA:GO_Central.
DR GO; GO:0000472; P:endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA); IBA:GO_Central.
DR GO; GO:0000056; P:ribosomal small subunit export from nucleus; IBA:GO_Central.
DR Gene3D; 1.25.10.10; -; 3.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR040000; NOP9.
DR InterPro; IPR001313; Pumilio_RNA-bd_rpt.
DR PANTHER; PTHR13102; PTHR13102; 1.
DR Pfam; PF00806; PUF; 3.
DR SMART; SM00025; Pumilio; 7.
DR SUPFAM; SSF48371; SSF48371; 1.
PE 3: Inferred from homology;
KW Nucleus; Reference proteome; Repeat; Ribosome biogenesis; rRNA processing.
FT CHAIN 1..724
FT /note="Nucleolar protein 9"
FT /id="PRO_0000407837"
FT REPEAT 147..183
FT /note="Pumilio 1"
FT REPEAT 204..239
FT /note="Pumilio 2"
FT REPEAT 291..328
FT /note="Pumilio 3"
FT REPEAT 340..375
FT /note="Pumilio 4"
FT REPEAT 376..412
FT /note="Pumilio 5"
FT REPEAT 513..549
FT /note="Pumilio 6"
FT REPEAT 550..587
FT /note="Pumilio 7"
FT REGION 1..23
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 39..61
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 235..258
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 649..724
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 235..249
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 703..724
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 724 AA; 80991 MW; 053B585DD6F59AE2 CRC64;
MPREVKKRGR RAAAKRAEEE KEDVDLKVYE NDEDYVTFDA DGGVAGGHDD EENDGYDNET
PYNPLDLKQM PFFGFLDDQE SEYFKTAEST LAVDAFGSPE EKLGFISGLL DEARGKELKL
VTNQICSKLM ERLILLANDE QIRALFEVFS GYFVDLSRHK YSSHCVETLL VRGAAIVEKE
VLDPNFDGDS EDSMEKRFLT LANDMKDYIQ DLISNPYASH VIRVLLLILG GQTLPSPTSS
EGNSSVLRSK KSRTARRNID IKDSEENDRA YQIPGAFHDA LEAIVSGFSK RLKPTAAREL
AIGQVSSPVV QLLIDSEATT SEQRPLLNTI FADTEDRDSS EEAFVEHLLS DAVGSHFLQN
VLQKAPEAFV ERLYRLYMSQ RVQKLVRRDY AGFVIETCMQ RLPEADVHHI IDTAMGEIPY
LVENNNLTMV RILLTRAAAA NYKATDVANA VLKTFDTDST DPKLLQKVLQ LDEKNPYKPH
EASSPGLHRC LVLQQLVEAS PEVLATAFVG LNSGDVDVIK MAKHQSYSRL LEKCLRPSIN
TIERRKFLNK INGQCVDLAR DPFASHVMDR LWNFTYKMNN FREKIANELV ADEDLKENTY
GKAVWRNWSL DKFLRRKSDW WVTLHATDDA LAKEYEELGI PLDAKSLANP GQKRFGRGGA
RIITRGGGTF PRGGGRGRGG FRGGRGGAPR GGFGGSDRGG FKRANGGDGE DASGDRSRKK
VRNE
