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NOP9_YEAS8
ID   NOP9_YEAS8              Reviewed;         666 AA.
AC   C8ZBK1;
DT   03-MAY-2011, integrated into UniProtKB/Swiss-Prot.
DT   20-APR-2010, sequence version 2.
DT   25-MAY-2022, entry version 51.
DE   RecName: Full=Nucleolar protein 9;
DE   AltName: Full=Pumilio domain-containing protein NOP9;
GN   Name=NOP9; ORFNames=EC1118_1J11_2476g;
OS   Saccharomyces cerevisiae (strain Lalvin EC1118 / Prise de mousse) (Baker's
OS   yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Saccharomyces.
OX   NCBI_TaxID=643680;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Lalvin EC1118 / Prise de mousse;
RX   PubMed=19805302; DOI=10.1073/pnas.0904673106;
RA   Novo M., Bigey F., Beyne E., Galeote V., Gavory F., Mallet S., Cambon B.,
RA   Legras J.-L., Wincker P., Casaregola S., Dequin S.;
RT   "Eukaryote-to-eukaryote gene transfer events revealed by the genome
RT   sequence of the wine yeast Saccharomyces cerevisiae EC1118.";
RL   Proc. Natl. Acad. Sci. U.S.A. 106:16333-16338(2009).
CC   -!- FUNCTION: RNA-binding nucleolar protein required for pre-rRNA
CC       processing. Component of the 90S pre-ribosome involved in production of
CC       18S rRNA and assembly of small ribosomal subunit. Component of the pre-
CC       40S ribosome required for release from the nucleolus (By similarity).
CC       {ECO:0000250}.
CC   -!- SUBUNIT: Component of the 90S pre-ribosome. Component of the pre-40S
CC       ribosome. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus, nucleolus {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the NOP9 family. {ECO:0000305}.
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DR   EMBL; FN393075; CAY80767.2; -; Genomic_DNA.
DR   AlphaFoldDB; C8ZBK1; -.
DR   SMR; C8ZBK1; -.
DR   EnsemblFungi; CAY80767; CAY80767; EC1118_1J11_2476g.
DR   HOGENOM; CLU_008720_1_1_1; -.
DR   Proteomes; UP000000286; Chromosome X, Scaffold EC1118_1J11.
DR   GO; GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR   GO; GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.
DR   Gene3D; 1.25.10.10; -; 3.
DR   InterPro; IPR011989; ARM-like.
DR   InterPro; IPR016024; ARM-type_fold.
DR   InterPro; IPR040000; NOP9.
DR   InterPro; IPR001313; Pumilio_RNA-bd_rpt.
DR   PANTHER; PTHR13102; PTHR13102; 1.
DR   SMART; SM00025; Pumilio; 8.
DR   SUPFAM; SSF48371; SSF48371; 1.
PE   3: Inferred from homology;
KW   Nucleus; Repeat; Ribosome biogenesis; rRNA processing.
FT   CHAIN           1..666
FT                   /note="Nucleolar protein 9"
FT                   /id="PRO_0000407841"
FT   REPEAT          92..127
FT                   /note="Pumilio 1"
FT   REPEAT          128..163
FT                   /note="Pumilio 2"
FT   REPEAT          188..223
FT                   /note="Pumilio 3"
FT   REPEAT          286..326
FT                   /note="Pumilio 4"
FT   REPEAT          334..369
FT                   /note="Pumilio 5"
FT   REPEAT          370..407
FT                   /note="Pumilio 6"
FT   REPEAT          511..548
FT                   /note="Pumilio 7"
FT   REPEAT          549..587
FT                   /note="Pumilio 8"
FT   REGION          1..40
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          635..666
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        641..660
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   666 AA;  77722 MW;  F6F8B3CD74DB2AB3 CRC64;
     MGKTKTRGRR HQDKQRKDEF EPSSNSAKEH IQQEESTYND EAEIKETQPQ MFFGVLDREE
     LEYFKQAEST LQLDAFEAPE EKFQFVTSII EEAKGKELKL VTSQITSKLM ERVILECDET
     QLKDIFQSFN GVFFGLSCHK YASHVLETLF VRSAALVERE LLTPSFDNNE KEGPYVTMEN
     MFLFMLNELK PHLKTMMNHQ YASHVLRLLI LILSSKTLPN STKANSTLRS KKSKIARKMI
     DIKDNDDFNK VYQTPESFKS ELRDIITTLY KGFTNGAESR SDISQSTITK FREYSVDKVA
     SPVIQLIIQV EGIFDRDRSF WRLVFNTADE KDPKEESFLE YLLSDPVGSH FLENVIGSAR
     LKYVERLYRL YMKDRIVKLA KRDTTGAFVV RALLEHLKEK DVKQILDAVV PELSMLLNSN
     MDFGTAIINA SNKQGGYLRD DVIAQLIQKY YPEKSDAKNI LESCLLLSAS TLGNTRDDWP
     TAEERRRSVF LEQLIDYDDK FLNITIDSML ALPEERLIQM CYHGVFSHVV EHVLQTTRVD
     IIKRKMLLNI LSKESVNLAC NVYGSHIMDK LWEFTAKLTL YKERIARALV LETEKVKNSI
     YGRQVWKNWK LELYVRKMWD WKKLIKEQEF EIFPNSKPLQ PKPEKHSRER NNSKEGSAFK
     KQKHYR
 
 
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