ID   NORR_SERP5              Reviewed;         507 AA.
AC   A8GG93;
DT   10-JUN-2008, integrated into UniProtKB/Swiss-Prot.
DT   10-JUN-2008, sequence version 2.
DT   03-AUG-2022, entry version 88.
DE   RecName: Full=Anaerobic nitric oxide reductase transcription regulator NorR {ECO:0000255|HAMAP-Rule:MF_01314};
GN   Name=norR {ECO:0000255|HAMAP-Rule:MF_01314}; OrderedLocusNames=Spro_3032;
OS   Serratia proteamaculans (strain 568).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Yersiniaceae; Serratia.
OX   NCBI_TaxID=399741;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=568;
RG   US DOE Joint Genome Institute;
RA   Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Dalin E.,
RA   Tice H., Pitluck S., Chain P., Malfatti S., Shin M., Vergez L., Schmutz J.,
RA   Larimer F., Land M., Hauser L., Kyrpides N., Kim E., Taghavi S., Newman L.,
RA   Vangronsveld J., van der Lelie D., Richardson P.;
RT   "Complete sequence of chromosome of Serratia proteamaculans 568.";
RL   Submitted (SEP-2007) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Required for the expression of anaerobic nitric oxide (NO)
CC       reductase, acts as a transcriptional activator for at least the norVW
CC       operon. Activation also requires sigma-54. {ECO:0000255|HAMAP-
CC       Rule:MF_01314}.
CC   -!- PATHWAY: Nitrogen metabolism; nitric oxide reduction.
CC       {ECO:0000255|HAMAP-Rule:MF_01314}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=ABV42133.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR   EMBL; CP000826; ABV42133.1; ALT_INIT; Genomic_DNA.
DR   RefSeq; WP_041418605.1; NC_009832.1.
DR   AlphaFoldDB; A8GG93; -.
DR   SMR; A8GG93; -.
DR   STRING; 399741.Spro_3032; -.
DR   EnsemblBacteria; ABV42133; ABV42133; Spro_3032.
DR   KEGG; spe:Spro_3032; -.
DR   eggNOG; COG3604; Bacteria.
DR   HOGENOM; CLU_000445_125_0_6; -.
DR   OrthoDB; 123059at2; -.
DR   UniPathway; UPA00638; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0000160; P:phosphorelay signal transduction system; IEA:UniProtKB-UniRule.
DR   Gene3D; 3.30.450.40; -; 1.
DR   Gene3D; 3.40.50.300; -; 1.
DR   HAMAP; MF_01314; NorR; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR003018; GAF.
DR   InterPro; IPR029016; GAF-like_dom_sf.
DR   InterPro; IPR009057; Homeobox-like_sf.
DR   InterPro; IPR023944; NorR.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR002078; Sigma_54_int.
DR   InterPro; IPR025662; Sigma_54_int_dom_ATP-bd_1.
DR   InterPro; IPR025943; Sigma_54_int_dom_ATP-bd_2.
DR   InterPro; IPR025944; Sigma_54_int_dom_CS.
DR   Pfam; PF01590; GAF; 1.
DR   Pfam; PF00158; Sigma54_activat; 1.
DR   SMART; SM00382; AAA; 1.
DR   SMART; SM00065; GAF; 1.
DR   SUPFAM; SSF46689; SSF46689; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   PROSITE; PS00675; SIGMA54_INTERACT_1; 1.
DR   PROSITE; PS00676; SIGMA54_INTERACT_2; 1.
DR   PROSITE; PS00688; SIGMA54_INTERACT_3; 1.
DR   PROSITE; PS50045; SIGMA54_INTERACT_4; 1.
PE   3: Inferred from homology;
KW   ATP-binding; DNA-binding; Nucleotide-binding; Phosphoprotein;
KW   Transcription; Transcription regulation.
FT   CHAIN           1..507
FT                   /note="Anaerobic nitric oxide reductase transcription
FT                   regulator NorR"
FT                   /id="PRO_0000341322"
FT   DOMAIN          188..417
FT                   /note="Sigma-54 factor interaction"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01314"
FT   DNA_BIND        483..502
FT                   /note="H-T-H motif"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01314"
FT   BINDING         216..223
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01314"
FT   BINDING         279..288
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01314"
FT   MOD_RES         57
FT                   /note="4-aspartylphosphate"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01314"
SQ   SEQUENCE   507 AA;  55405 MW;  E2015B7B52AB0CE7 CRC64;
     MTLSIQSLAS IAIELQSGLT QRDRFQRLIN SLRSLLRCDA SALLRFEGQQ FRPLAIDGLA
     QDVLGRRFAL DAHPRLEAIA RAGGVVRFPA DSELPDPYDG LIPGHDQLKV HACIGLPLFA
     EQDLIGALTF DSLDPMQFDR FSDEELRLIS ALAAGALNNA LLVEALERQA LSPLASPGGS
     SPRENDEIIG LSSVMQQLKQ EISIVAGSEL NVLITGETGV GKELVVRAIH QGSARAANPL
     VYLNCAALPE SVAESELFGH VKGAFTGAIQ HRAGKFEMAD NGTLFLDEIG ELSLSLQAKL
     LRVIQYGDLQ RVGDDRVKRV NVRILAATNR DLKQAAVDGA FRLDLYHRLS VFPLAVPPLR
     ERVSDIALLA GYFCERCRIK LGLMQLTLSV QALSALEQYS WPGNIRELEH SIYRAAILAR
     AEQSSSELQL LPAHFTIKAG ALPARIIDDA LPESAIGVSL ATLTQHFQRS VIEKTLVECE
     MNWAATARKL ELDSGNLHRL AKRLNMK