ID   NOSR_PSEAE              Reviewed;         715 AA.
AC   Q9HYL3;
DT   11-JAN-2001, integrated into UniProtKB/Swiss-Prot.
DT   11-JAN-2001, sequence version 1.
DT   03-AUG-2022, entry version 115.
DE   RecName: Full=Regulatory protein NosR;
GN   Name=nosR; OrderedLocusNames=PA3391;
OS   Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM
OS   14847 / LMG 12228 / 1C / PRS 101 / PAO1).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Pseudomonadales;
OC   Pseudomonadaceae; Pseudomonas.
OX   NCBI_TaxID=208964;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C /
RC   PRS 101 / PAO1;
RX   PubMed=10984043; DOI=10.1038/35023079;
RA   Stover C.K., Pham X.-Q.T., Erwin A.L., Mizoguchi S.D., Warrener P.,
RA   Hickey M.J., Brinkman F.S.L., Hufnagle W.O., Kowalik D.J., Lagrou M.,
RA   Garber R.L., Goltry L., Tolentino E., Westbrock-Wadman S., Yuan Y.,
RA   Brody L.L., Coulter S.N., Folger K.R., Kas A., Larbig K., Lim R.M.,
RA   Smith K.A., Spencer D.H., Wong G.K.-S., Wu Z., Paulsen I.T., Reizer J.,
RA   Saier M.H. Jr., Hancock R.E.W., Lory S., Olson M.V.;
RT   "Complete genome sequence of Pseudomonas aeruginosa PAO1, an opportunistic
RT   pathogen.";
RL   Nature 406:959-964(2000).
CC   -!- FUNCTION: Transcriptional activator of the nitrous-oxide reductase gene
CC       NosZ.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Peripheral membrane
CC       protein {ECO:0000305}.
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DR   EMBL; AE004091; AAG06779.1; -; Genomic_DNA.
DR   PIR; B83222; B83222.
DR   RefSeq; NP_252081.1; NC_002516.2.
DR   RefSeq; WP_004345196.1; NZ_QZGE01000017.1.
DR   AlphaFoldDB; Q9HYL3; -.
DR   STRING; 287.DR97_4531; -.
DR   PaxDb; Q9HYL3; -.
DR   PRIDE; Q9HYL3; -.
DR   EnsemblBacteria; AAG06779; AAG06779; PA3391.
DR   GeneID; 879823; -.
DR   KEGG; pae:PA3391; -.
DR   PATRIC; fig|208964.12.peg.3550; -.
DR   PseudoCAP; PA3391; -.
DR   HOGENOM; CLU_013077_0_0_6; -.
DR   InParanoid; Q9HYL3; -.
DR   OMA; RLWPIKY; -.
DR   PhylomeDB; Q9HYL3; -.
DR   BioCyc; PAER208964:G1FZ6-3457-MON; -.
DR   Proteomes; UP000002438; Chromosome.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0010181; F:FMN binding; IEA:InterPro.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IEA:InterPro.
DR   InterPro; IPR017896; 4Fe4S_Fe-S-bd.
DR   InterPro; IPR007329; FMN-bd.
DR   InterPro; IPR011399; NosR.
DR   Pfam; PF12801; Fer4_5; 2.
DR   Pfam; PF04205; FMN_bind; 1.
DR   PIRSF; PIRSF036354; NosR; 1.
DR   SMART; SM00900; FMN_bind; 1.
PE   4: Predicted;
KW   Activator; Cell membrane; DNA-binding; Membrane; Reference proteome;
KW   Transcription; Transcription regulation.
FT   CHAIN           1..715
FT                   /note="Regulatory protein NosR"
FT                   /id="PRO_0000057966"
FT   DNA_BIND        210..229
FT                   /note="H-T-H motif"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   715 AA;  80244 MW;  EDF4926C5875DF0A CRC64;
     MRALRFSAGS WRCVFAWMLL LVGLAAQGAE LSELERLRIA QVFPAVERIG DPEGDYGVRR
     LSKGEETLGY AFQTLSVTDI PAYSGKPINL QVILDPQAVI RDAYVLEHHE PILLIGIPEE
     KLHAFSARYD GVRADQRVVV GRSSDPQAVT VDAVSGATVT VMVVNEIVMR AAHTVAVALG
     LIEDRGNVRP KPAQVRQQPA ATASWSELLG NGAIRRLQLS RGQIDDAFKG SEAEGIGEAD
     AAHRDEPFID LYSALLNPPA VGRSLLGDNQ YRELMASLKP GEYAFVVLGD GEYSFKGSGY
     VRGGIFDRVQ LRQFGDIISF RDLDYQRLSD VYAEGMPEFR EMAIFVARAS QRFDPGSPWT
     LELLVRRQTG PVAGVFTSFE LACQTPEEYL ERPQPTAEEL AALEEAARPL WLRVWYQKSF
     QVGVLCTALV LLLAILFLQD RLVRRPRLMQ RLRTGYLAFT LVYLGWYSLG QLSVVNVLTF
     VHALFEGFRW ELFLSDPLLF ILWTFTAASL LLWGRGVFCG WLCPFGALQE LLNELARKLR
     VPQFQVPFAV HERLWAIKYI ILLVLFGLSL ESLALAEQAA EVEPFKTAIT LGFDRQWWFV
     AYAVALLVVN LFTRKVYCRY LCPLGAALAI PAKARLFDWL KRRAECGRPC QLCARECEIQ
     AIHPDGRIEA NECHYCLDCQ MTYHDQDKCP PLVNKRKKRA KSAPADNARI PAENL