ID   NOT1B_DANRE             Reviewed;         139 AA.
AC   Q6DFZ6;
DT   29-APR-2015, integrated into UniProtKB/Swiss-Prot.
DT   16-AUG-2004, sequence version 1.
DT   03-AUG-2022, entry version 61.
DE   RecName: Full=Inactive palmitoleoyl-protein carboxylesterase notum1b {ECO:0000250|UniProtKB:Q6P988};
GN   Name=notum1b {ECO:0000312|ZFIN:ZDB-GENE-040718-391};
GN   ORFNames=zgc:92474 {ECO:0000303|Ref.2};
OS   Danio rerio (Zebrafish) (Brachydanio rerio).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;
OC   Danionidae; Danioninae; Danio.
OX   NCBI_TaxID=7955;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Tuebingen;
RX   PubMed=23594743; DOI=10.1038/nature12111;
RA   Howe K., Clark M.D., Torroja C.F., Torrance J., Berthelot C., Muffato M.,
RA   Collins J.E., Humphray S., McLaren K., Matthews L., McLaren S., Sealy I.,
RA   Caccamo M., Churcher C., Scott C., Barrett J.C., Koch R., Rauch G.J.,
RA   White S., Chow W., Kilian B., Quintais L.T., Guerra-Assuncao J.A., Zhou Y.,
RA   Gu Y., Yen J., Vogel J.H., Eyre T., Redmond S., Banerjee R., Chi J., Fu B.,
RA   Langley E., Maguire S.F., Laird G.K., Lloyd D., Kenyon E., Donaldson S.,
RA   Sehra H., Almeida-King J., Loveland J., Trevanion S., Jones M., Quail M.,
RA   Willey D., Hunt A., Burton J., Sims S., McLay K., Plumb B., Davis J.,
RA   Clee C., Oliver K., Clark R., Riddle C., Elliot D., Threadgold G.,
RA   Harden G., Ware D., Begum S., Mortimore B., Kerry G., Heath P.,
RA   Phillimore B., Tracey A., Corby N., Dunn M., Johnson C., Wood J., Clark S.,
RA   Pelan S., Griffiths G., Smith M., Glithero R., Howden P., Barker N.,
RA   Lloyd C., Stevens C., Harley J., Holt K., Panagiotidis G., Lovell J.,
RA   Beasley H., Henderson C., Gordon D., Auger K., Wright D., Collins J.,
RA   Raisen C., Dyer L., Leung K., Robertson L., Ambridge K., Leongamornlert D.,
RA   McGuire S., Gilderthorp R., Griffiths C., Manthravadi D., Nichol S.,
RA   Barker G., Whitehead S., Kay M., Brown J., Murnane C., Gray E.,
RA   Humphries M., Sycamore N., Barker D., Saunders D., Wallis J., Babbage A.,
RA   Hammond S., Mashreghi-Mohammadi M., Barr L., Martin S., Wray P.,
RA   Ellington A., Matthews N., Ellwood M., Woodmansey R., Clark G., Cooper J.,
RA   Tromans A., Grafham D., Skuce C., Pandian R., Andrews R., Harrison E.,
RA   Kimberley A., Garnett J., Fosker N., Hall R., Garner P., Kelly D., Bird C.,
RA   Palmer S., Gehring I., Berger A., Dooley C.M., Ersan-Urun Z., Eser C.,
RA   Geiger H., Geisler M., Karotki L., Kirn A., Konantz J., Konantz M.,
RA   Oberlander M., Rudolph-Geiger S., Teucke M., Lanz C., Raddatz G.,
RA   Osoegawa K., Zhu B., Rapp A., Widaa S., Langford C., Yang F.,
RA   Schuster S.C., Carter N.P., Harrow J., Ning Z., Herrero J., Searle S.M.,
RA   Enright A., Geisler R., Plasterk R.H., Lee C., Westerfield M.,
RA   de Jong P.J., Zon L.I., Postlethwait J.H., Nusslein-Volhard C.,
RA   Hubbard T.J., Roest Crollius H., Rogers J., Stemple D.L.;
RT   "The zebrafish reference genome sequence and its relationship to the human
RT   genome.";
RL   Nature 496:498-503(2013).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RG   NIH - Zebrafish Gene Collection (ZGC) project;
RL   Submitted (JUL-2004) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Probable inactive palmitoleoyl-protein carboxylesterase.
CC       {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the pectinacetylesterase family. Notum
CC       subfamily. {ECO:0000305}.
CC   -!- CAUTION: In contrast to other members of the family, lacks the active
CC       sites for palmitoleoyl-protein carboxylesterase activity, suggesting it
CC       has no activity.
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DR   EMBL; CABZ01094849; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; BC076559; AAH76559.1; -; mRNA.
DR   RefSeq; NP_001002644.1; NM_001002644.1.
DR   AlphaFoldDB; Q6DFZ6; -.
DR   SMR; Q6DFZ6; -.
DR   GeneID; 436917; -.
DR   KEGG; dre:436917; -.
DR   CTD; 436917; -.
DR   ZFIN; ZDB-GENE-040718-391; notum1b.
DR   eggNOG; KOG4287; Eukaryota.
DR   OrthoDB; 610784at2759; -.
DR   PhylomeDB; Q6DFZ6; -.
DR   PRO; PR:Q6DFZ6; -.
DR   Proteomes; UP000000437; Genome assembly.
DR   Proteomes; UP000814640; Unplaced.
DR   GO; GO:1990699; F:palmitoleyl hydrolase activity; ISS:UniProtKB.
DR   GO; GO:0090090; P:negative regulation of canonical Wnt signaling pathway; IBA:GO_Central.
DR   GO; GO:0030178; P:negative regulation of Wnt signaling pathway; ISS:UniProtKB.
DR   GO; GO:1990697; P:protein depalmitoleylation; ISS:UniProtKB.
DR   InterPro; IPR004963; PAE/NOTUM.
DR   PANTHER; PTHR21562; PTHR21562; 1.
DR   Pfam; PF03283; PAE; 1.
PE   2: Evidence at transcript level;
KW   Reference proteome.
FT   CHAIN           1..139
FT                   /note="Inactive palmitoleoyl-protein carboxylesterase
FT                   notum1b"
FT                   /id="PRO_0000432992"
SQ   SEQUENCE   139 AA;  15809 MW;  BF0BFA58BDFC086C CRC64;
     MAQVKSLAQS LYPCSSQRLE HQMKLQILKN SSVTCNDGTP AGYYIKESRG SRRWLVFLEG
     GWYCFSKHTC DSRYESMRRL MSSSNWPPTR TGTGILSPQP EENPHWWNAN TVFVPYCSSD
     VWSGSTPKTD QRGHQGALN