ID   NP03_HHV2H              Reviewed;         233 AA.
AC   P28279; O12511; Q89644;
DT   01-DEC-1992, integrated into UniProtKB/Swiss-Prot.
DT   07-JUN-2005, sequence version 2.
DT   02-JUN-2021, entry version 66.
DE   RecName: Full=Nuclear phosphoprotein UL3;
GN   ORFNames=UL3;
OS   Human herpesvirus 2 (strain HG52) (HHV-2) (Human herpes simplex virus 2).
OC   Viruses; Duplodnaviria; Heunggongvirae; Peploviricota; Herviviricetes;
OC   Herpesvirales; Herpesviridae; Alphaherpesvirinae; Simplexvirus.
OX   NCBI_TaxID=10315;
OH   NCBI_TaxID=9606; Homo sapiens (Human).
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=1662697; DOI=10.1099/0022-1317-72-12-3057;
RA   McGeoch D.J., Cunningham C., McIntyre G., Dolan A.;
RT   "Comparative sequence analysis of the long repeat regions and adjoining
RT   parts of the long unique regions in the genomes of herpes simplex viruses
RT   types 1 and 2.";
RL   J. Gen. Virol. 72:3057-3075(1991).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=9499055; DOI=10.1128/jvi.72.3.2010-2021.1998;
RA   Dolan A., Jamieson F.E., Cunningham C., Barnett B.C., McGeoch D.J.;
RT   "The genome sequence of herpes simplex virus type 2.";
RL   J. Virol. 72:2010-2021(1998).
CC   -!- SUBCELLULAR LOCATION: Host nucleus {ECO:0000250}. Note=Has a
CC       perinuclear location early in infection and at later times becomes
CC       associated with the nucleus as discrete particles. {ECO:0000250}.
CC   -!- PTM: Phosphorylated. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the alphaherpesvirinae HHV-1 UL3 family.
CC       {ECO:0000305}.
CC   -!- CAUTION: It is uncertain whether Met-1 or Met-12 is the initiator.
CC       {ECO:0000305}.
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DR   EMBL; D10470; BAA01266.1; -; Genomic_DNA.
DR   EMBL; Z86099; CAB06763.1; -; Genomic_DNA.
DR   PIR; JQ1496; WMBEHK.
DR   PRIDE; P28279; -.
DR   Proteomes; UP000001874; Genome.
DR   GO; GO:0042025; C:host cell nucleus; IEA:UniProtKB-SubCell.
DR   InterPro; IPR005035; Herpes_UL3.
DR   Pfam; PF03369; Herpes_UL3; 1.
PE   3: Inferred from homology;
KW   Host nucleus; Phosphoprotein; Reference proteome.
FT   CHAIN           1..233
FT                   /note="Nuclear phosphoprotein UL3"
FT                   /id="PRO_0000115894"
FT   REGION          38..88
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        39..53
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   CONFLICT        41..43
FT                   /note="PGA -> LAR (in Ref. 1; BAA01266)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   233 AA;  25534 MW;  314982C654BC3554 CRC64;
     MVKSRVSYRS VMSGVGEERV PSAFTILASW GWTFAPQNHD PGASPNTTPI ESIAGTAPDA
     HVGPLDGEPD RDAISPLTSS VAGDPPGADG PYVTFDTLFM VSSIDELGRR QLTDTIRKDL
     RLSLAKFSIA CTKTSSFSGT AARQRKRGAP PQRTCVPRSN KSLQMFVLCK RANAAQVREQ
     LRAVIRSRKP RKYYTRSSDG RLCPAVPVFV HEFVSSEPMR LHRDNVMLST EPD