ID   NP04_VZVO               Reviewed;         243 AA.
AC   Q9J3N4;
DT   22-SEP-2009, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-2000, sequence version 1.
DT   02-JUN-2021, entry version 34.
DE   RecName: Full=Nuclear protein UL4 homolog;
DE   AltName: Full=ORF56 protein;
GN   ORFNames=ORF56;
OS   Varicella-zoster virus (strain Oka vaccine) (HHV-3) (Human herpesvirus 3).
OC   Viruses; Duplodnaviria; Heunggongvirae; Peploviricota; Herviviricetes;
OC   Herpesvirales; Herpesviridae; Alphaherpesvirinae; Varicellovirus.
OX   NCBI_TaxID=341980;
OH   NCBI_TaxID=9606; Homo sapiens (Human).
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=Oka varicella vaccine Biken (V-Oka-Biken);
RX   PubMed=10720545; DOI=10.1086/315335;
RA   Argaw T., Cohen J.I., Klutch M., Lekstrom K., Yoshikawa T., Asano Y.,
RA   Krause P.R.;
RT   "Nucleotide sequences that distinguish Oka vaccine from parental Oka and
RT   other varicella-zoster virus isolates.";
RL   J. Infect. Dis. 181:1153-1157(2000).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Isolate Human/Japan/P-Oka/1970, and
RC   Oka varicella vaccine Biken (V-Oka-Biken);
RX   PubMed=12388706; DOI=10.1128/jvi.76.22.11447-11459.2002;
RA   Gomi Y., Sunamachi H., Mori Y., Nagaike K., Takahashi M., Yamanishi K.;
RT   "Comparison of the complete DNA sequences of the Oka varicella vaccine and
RT   its parental virus.";
RL   J. Virol. 76:11447-11459(2002).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Oka varicella vaccine VarilRix (V-Oka-GSK), and
RC   Oka varicella vaccine Varivax (V-Oka-Merk);
RX   PubMed=18787000; DOI=10.1128/jvi.00777-08;
RA   Tillieux S.L., Halsey W.S., Thomas E.S., Voycik J.J., Sathe G.M.,
RA   Vassilev V.;
RT   "Complete DNA sequences of two oka strain varicella-zoster virus genomes.";
RL   J. Virol. 82:11023-11044(2008).
CC   -!- SUBCELLULAR LOCATION: Host nucleus {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the alphaherpesvirinae HHV-1 UL4 family.
CC       {ECO:0000305}.
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DR   EMBL; AF206304; AAF61657.1; -; Genomic_DNA.
DR   EMBL; AB097932; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AB097933; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; DQ008354; AAY57665.1; -; Genomic_DNA.
DR   EMBL; DQ008355; AAY57736.1; -; Genomic_DNA.
DR   IntAct; Q9J3N4; 21.
DR   MINT; Q9J3N4; -.
DR   Proteomes; UP000002603; Genome.
DR   Proteomes; UP000008504; Genome.
DR   Proteomes; UP000008505; Genome.
DR   Proteomes; UP000008506; Genome.
DR   GO; GO:0042025; C:host cell nucleus; IEA:UniProtKB-SubCell.
DR   InterPro; IPR004958; Herpes_UL4.
DR   Pfam; PF03277; Herpes_UL4; 1.
PE   3: Inferred from homology;
KW   Host nucleus.
FT   CHAIN           1..243
FT                   /note="Nuclear protein UL4 homolog"
FT                   /id="PRO_0000385488"
FT   REGION          193..226
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        194..224
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   243 AA;  27080 MW;  675949F873BC93EC CRC64;
     MKNPQKLAIT FLPLYVIPTY TLCIKALYKN THAGLLFSFL GFVLNTPAMS ISGPPTTFIL
     YRLHGVRRVL HWTLPDHEQT LYAFTGGSRS MAVKTDARCD TMSGGMIVLQ HTHTVTLLTI
     DCSTDFSSYA FTHRDFHLQD KPHATFAMPF MSWVGSDPTS QLYSNVGGVL SVITEDDLSM
     CISIVIYGLR VNRPDDQTTP TPTPHQYTSQ RRQPETNCPS PQPAFFTSDD DVLSLILRDA
     ANA