ID   NP1_HBOC3               Reviewed;         218 AA.
AC   C1IWT1;
DT   07-NOV-2018, integrated into UniProtKB/Swiss-Prot.
DT   26-MAY-2009, sequence version 1.
DT   02-JUN-2021, entry version 22.
DE   RecName: Full=Non-structural protein NP-1;
DE            Short=NP1;
GN   Name=NP1; Synonyms=NP-1;
OS   Human bocavirus 3 (HBoV3) (Adelavirus W471).
OC   Viruses; Monodnaviria; Shotokuvirae; Cossaviricota; Quintoviricetes;
OC   Piccovirales; Parvoviridae; Parvovirinae; Bocaparvovirus;
OC   Primate bocaparvovirus 1.
OX   NCBI_TaxID=638313;
OH   NCBI_TaxID=9606; Homo sapiens (Human).
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Arthur J.L., Higgins G.D., Davidson G.P., Givney R.C., Ratcliff R.M.;
RT   "A Novel Bocavirus Associated with Acute Gastroenteritis in Australian
RT   Children.";
RL   PLoS Pathog. 5:E1000391-E1000391(2009).
CC   -!- FUNCTION: Required for the expression of the capsid proteins. Performs
CC       the splicing and internal polyadenylation of the viral capsid-encoding
CC       mRNA precursor, which allows its maturation and expression.
CC       Transactivates the viral promoter. {ECO:0000250|UniProtKB:Q3YPH5}.
CC   -!- SUBCELLULAR LOCATION: Host nucleus {ECO:0000250|UniProtKB:Q3YPH5}.
CC   -!- SIMILARITY: Belongs to the Bocaparvovirus Non-structural protein NP-1
CC       family. {ECO:0000305}.
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DR   EMBL; EU918736; ACH81928.1; -; Genomic_DNA.
DR   RefSeq; YP_002808455.1; NC_012564.1.
DR   GeneID; 7768237; -.
DR   KEGG; vg:7768237; -.
DR   Proteomes; UP000128541; Genome.
DR   GO; GO:0042025; C:host cell nucleus; IEA:UniProtKB-SubCell.
DR   InterPro; IPR021075; Bocavirus_NP1.
DR   Pfam; PF11733; NP1-WLL; 1.
PE   3: Inferred from homology;
KW   Activator; Host nucleus; Transcription; Transcription regulation.
FT   CHAIN           1..218
FT                   /note="Non-structural protein NP-1"
FT                   /id="PRO_0000445639"
FT   REGION          1..89
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          195..218
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        15..29
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        41..75
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   218 AA;  25379 MW;  07F68417D3E244AC CRC64;
     MSSGNTKDKH RAYKRKGSPG RDERKRPWQP HHRSRSRSPI RRSGETSSGS YRQEHQISHL
     SSCTASKISD PVTKTKENTS GKRDSRTNPY TVFSQHKASH PDAPGWCGFY WHSTRIARNG
     TNAIFNEMKQ QFQQLQLDNK IGWDSARELL FSQKKSLDQQ YRNMFWHFRN ASDCERCNYW
     DNVYRMHLAH VSSQTESEEI TDEEMLSAAE SMETDASN