ID   NP93A_ARATH             Reviewed;         861 AA.
AC   O22224; Q94CF2;
DT   01-DEC-2000, integrated into UniProtKB/Swiss-Prot.
DT   20-JUN-2002, sequence version 2.
DT   03-AUG-2022, entry version 129.
DE   RecName: Full=Nuclear pore complex protein NUP93A {ECO:0000303|PubMed:21189294};
DE   AltName: Full=Nucleoporin 93A;
GN   Name=NUP93A {ECO:0000303|PubMed:21189294};
GN   OrderedLocusNames=At2g41620 {ECO:0000312|Araport:AT2G41620};
GN   ORFNames=T32G6.14 {ECO:0000312|EMBL:AAB84345.2};
OS   Arabidopsis thaliana (Mouse-ear cress).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX   NCBI_TaxID=3702;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Columbia;
RX   PubMed=10617197; DOI=10.1038/45471;
RA   Lin X., Kaul S., Rounsley S.D., Shea T.P., Benito M.-I., Town C.D.,
RA   Fujii C.Y., Mason T.M., Bowman C.L., Barnstead M.E., Feldblyum T.V.,
RA   Buell C.R., Ketchum K.A., Lee J.J., Ronning C.M., Koo H.L., Moffat K.S.,
RA   Cronin L.A., Shen M., Pai G., Van Aken S., Umayam L., Tallon L.J.,
RA   Gill J.E., Adams M.D., Carrera A.J., Creasy T.H., Goodman H.M.,
RA   Somerville C.R., Copenhaver G.P., Preuss D., Nierman W.C., White O.,
RA   Eisen J.A., Salzberg S.L., Fraser C.M., Venter J.C.;
RT   "Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana.";
RL   Nature 402:761-768(1999).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Columbia;
RX   PubMed=27862469; DOI=10.1111/tpj.13415;
RA   Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA   Town C.D.;
RT   "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT   genome.";
RL   Plant J. 89:789-804(2017).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=cv. Columbia;
RX   PubMed=14593172; DOI=10.1126/science.1088305;
RA   Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA   Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA   Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA   Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA   Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA   Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA   Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA   Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA   Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA   Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA   Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA   Ecker J.R.;
RT   "Empirical analysis of transcriptional activity in the Arabidopsis
RT   genome.";
RL   Science 302:842-846(2003).
RN   [4]
RP   IDENTIFICATION ON 2D-GELS.
RC   STRAIN=cv. Columbia;
RA   Sarazin B., Tonella L., Marques K., Paesano S., Chane-Favre L., Heller M.,
RA   Sanchez J.-C., Hochstrasser D.F., Thiellement H.;
RL   Unpublished observations (SEP-2000).
RN   [5]
RP   IDENTIFICATION IN THE NUCLEAR PORE COMPLEX BY MASS SPECTROMETRY,
RP   SUBCELLULAR LOCATION, AND NOMENCLATURE.
RX   PubMed=21189294; DOI=10.1105/tpc.110.079947;
RA   Tamura K., Fukao Y., Iwamoto M., Haraguchi T., Hara-Nishimura I.;
RT   "Identification and characterization of nuclear pore complex components in
RT   Arabidopsis thaliana.";
RL   Plant Cell 22:4084-4097(2010).
CC   -!- SUBUNIT: Part of the nuclear pore complex (NPC). The NPC has an eight-
CC       fold symmetrical structure comprising a central transport channel and
CC       two rings, the cytoplasmic and nuclear rings, to which eight filaments
CC       are attached. The cytoplasmic filaments have loose ends, while the
CC       nuclear filaments are joined in a distal ring, forming a nuclear
CC       basket. NPCs are highly dynamic in configuration and composition, and
CC       can be devided in 3 subcomplexes, the NUP62 subcomplex, the NUP107-160
CC       subcomplex and the NUP93 subcomplex, containing approximately 30
CC       different nucleoporin proteins. {ECO:0000305|PubMed:21189294}.
CC   -!- SUBCELLULAR LOCATION: Nucleus envelope {ECO:0000269|PubMed:21189294}.
CC       Nucleus, nuclear pore complex {ECO:0000305|PubMed:21189294}.
CC   -!- SIMILARITY: Belongs to the nucleoporin interacting component (NIC)
CC       family. {ECO:0000305}.
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DR   EMBL; AC002510; AAB84345.2; -; Genomic_DNA.
DR   EMBL; CP002685; AEC10008.1; -; Genomic_DNA.
DR   EMBL; AY034907; AAK59414.1; -; mRNA.
DR   EMBL; AY113905; AAM44953.1; -; mRNA.
DR   PIR; T00818; T00818.
DR   RefSeq; NP_565951.1; NM_129725.5.
DR   AlphaFoldDB; O22224; -.
DR   SMR; O22224; -.
DR   BioGRID; 4097; 56.
DR   IntAct; O22224; 1.
DR   STRING; 3702.AT2G41620.1; -.
DR   iPTMnet; O22224; -.
DR   PaxDb; O22224; -.
DR   PRIDE; O22224; -.
DR   ProteomicsDB; 250514; -.
DR   EnsemblPlants; AT2G41620.1; AT2G41620.1; AT2G41620.
DR   GeneID; 818760; -.
DR   Gramene; AT2G41620.1; AT2G41620.1; AT2G41620.
DR   KEGG; ath:AT2G41620; -.
DR   Araport; AT2G41620; -.
DR   TAIR; locus:2062693; AT2G41620.
DR   eggNOG; KOG2168; Eukaryota.
DR   HOGENOM; CLU_017473_0_0_1; -.
DR   InParanoid; O22224; -.
DR   OMA; LLMCGQF; -.
DR   OrthoDB; 187731at2759; -.
DR   PhylomeDB; O22224; -.
DR   PRO; PR:O22224; -.
DR   Proteomes; UP000006548; Chromosome 2.
DR   ExpressionAtlas; O22224; baseline and differential.
DR   Genevisible; O22224; AT.
DR   GO; GO:0005635; C:nuclear envelope; IDA:TAIR.
DR   GO; GO:0005643; C:nuclear pore; IBA:GO_Central.
DR   GO; GO:0005730; C:nucleolus; HDA:TAIR.
DR   GO; GO:0009506; C:plasmodesma; HDA:TAIR.
DR   GO; GO:0017056; F:structural constituent of nuclear pore; IBA:GO_Central.
DR   GO; GO:0016973; P:poly(A)+ mRNA export from nucleus; IBA:GO_Central.
DR   GO; GO:0006606; P:protein import into nucleus; IBA:GO_Central.
DR   InterPro; IPR007231; Nucleoporin_int_Nup93/Nic96.
DR   PANTHER; PTHR11225; PTHR11225; 1.
DR   Pfam; PF04097; Nic96; 1.
PE   1: Evidence at protein level;
KW   mRNA transport; Nuclear pore complex; Nucleus; Protein transport;
KW   Reference proteome; Translocation; Transport.
FT   CHAIN           1..861
FT                   /note="Nuclear pore complex protein NUP93A"
FT                   /id="PRO_0000220600"
SQ   SEQUENCE   861 AA;  96615 MW;  9F53F0BFF013D673 CRC64;
     MANDQEMSGW TDLLHSSSKL LEQAAPSSQF PPLQRNLDQL EALSKKLKAK TLRNEAPSQS
     IAATRLLARE GINAEQLARD LKSFELKTTF EDVFPAEATS VEEYLQQVHE MAMVSAIQEA
     QKDNVRSFND YMMKVLEEDW RKEKRDFLQS LSRISMLPKT NMIDTSREAH AGQLVPVGSS
     PRVSSTPGKE LVALANIPIH EKKAYVYGEV VKKLNTSRER GMPFRPAMCF KDAYDTLGAE
     VTRGKSVNMQ KIWQLVQAIT GEDSAVRQGV SKRMALAIGA RHHLQHGHEK FIMDTIQTHP
     TQAALGGSVG NLQRIRAFLR IRLRDYGVLD FDSTDARRQP PVDTTWQQIY FCLRTGYYEE
     AREIARSTRS SQQFAPLLTE WITTDGMVAA ESAAIASEEC EKMLRMGDRL GRTAYDKKKL
     LLYTIISGSR RQIERILRDL STLFNTIEDF LWFKLSCIRD VTGGSSSVVL NDGLAPYSLD
     DLQAYLNKFE PSYYTKNGKD PLVYPYVLLL SVQLLPAIMH LSKEAGDGGY NIDAVHIAIS
     LVDHSVLSEG SGTGHKLSVM DSNAEASSMI RQYGSMFLHH GDLQMTVEYY AQAAATVGGG
     QLAWSGRSNV DQQRQRNLML KQLLTEILLR ERGIYFLLGA RGSGEEGQLG RFFPDSRLRQ
     QFLVEAAHQC QEAGLYDKSI ELQKRVGAFS AALETINKCL SEAICSLARG RLDGESRTSG
     LILAGNDILE TYKYYPEVSL QERERVMEQE TILRELEAIL SIHKLGRLGN HLDALREIAK
     LPFLHLDPRM PDATADVFQS ASPYFQTCVP DLLKVALTCL DNVPDTDGSI RAMRSKIAGF
     LASNTHRNWP RDLYEKVARS F