ID   NPAL3_PONAB             Reviewed;         406 AA.
AC   Q5RD30;
DT   27-JUN-2006, integrated into UniProtKB/Swiss-Prot.
DT   21-DEC-2004, sequence version 1.
DT   25-MAY-2022, entry version 52.
DE   RecName: Full=NIPA-like protein 3;
GN   Name=NIPAL3; Synonyms=NPAL3;
OS   Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC   Pongo.
OX   NCBI_TaxID=9601;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Kidney;
RG   The German cDNA consortium;
RL   Submitted (NOV-2004) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the NIPA family. {ECO:0000305}.
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DR   EMBL; CR858088; CAH90327.1; -; mRNA.
DR   RefSeq; NP_001125153.1; NM_001131681.1.
DR   AlphaFoldDB; Q5RD30; -.
DR   STRING; 9601.ENSPPYP00000001987; -.
DR   GeneID; 100172040; -.
DR   KEGG; pon:100172040; -.
DR   CTD; 57185; -.
DR   eggNOG; KOG2922; Eukaryota.
DR   InParanoid; Q5RD30; -.
DR   OrthoDB; 754939at2759; -.
DR   Proteomes; UP000001595; Unplaced.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0015095; F:magnesium ion transmembrane transporter activity; IEA:InterPro.
DR   InterPro; IPR008521; Mg_trans_NIPA.
DR   PANTHER; PTHR12570; PTHR12570; 1.
DR   Pfam; PF05653; Mg_trans_NIPA; 1.
PE   2: Evidence at transcript level;
KW   Glycoprotein; Membrane; Phosphoprotein; Reference proteome; Transmembrane;
KW   Transmembrane helix.
FT   CHAIN           1..406
FT                   /note="NIPA-like protein 3"
FT                   /id="PRO_0000242152"
FT   TRANSMEM        33..53
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        76..96
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        101..121
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        135..155
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        171..191
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        202..222
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        240..260
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        271..291
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        300..320
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   MOD_RES         372
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250|UniProtKB:Q6P499"
FT   CARBOHYD        166
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   406 AA;  44781 MW;  DDC84408729B5744 CRC64;
     MDGSHSAALQ LQQLPPTSSS SAMSEASFSY KENLIGALLA IFGHLVVSIA LNLQKYCHIR
     LAGSKDPRAY FKTKTWWLGL FLMLLGELGV FASYAFAPLS LIVPLSAVSV IASAIIGIIF
     IKEKWKPKDF LRRYILSFVG CGLAVVGTYL LVTFAPNSRE KMTGENVTRH LVSWPFLLYM
     LVEIILFCLL LYFYKEKNAN NIVVILLLVA LLGSMTVVTV KAVAGMLVLS IQGNLQLDYP
     IFYVMFVCMV ATAVYQAAFL SQASQMYDSS LIASVGYILS TTIAITAGAI FYLDFIGEDV
     LHICMFALGC LIAFLGVFLI TRNRKKAIPF EPYISMDAMP GMQNMHDKGM TVQPELKASF
     SYGALENNDN ISEIYAPATL PVMQEEHGSR SASGVPYRVL EHTKKE