ID   NPC2_MAGO7              Reviewed;         178 AA.
AC   Q52FS9; A4RKA8; G4MTH4;
DT   16-AUG-2005, integrated into UniProtKB/Swiss-Prot.
DT   16-AUG-2005, sequence version 2.
DT   25-MAY-2022, entry version 81.
DE   RecName: Full=Phosphatidylglycerol/phosphatidylinositol transfer protein;
DE            Short=PG/PI-TP;
DE   Flags: Precursor;
GN   Name=NPC2; ORFNames=MGG_01557;
OS   Magnaporthe oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958) (Rice blast
OS   fungus) (Pyricularia oryzae).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC   Sordariomycetidae; Magnaporthales; Pyriculariaceae; Pyricularia.
OX   NCBI_TaxID=242507;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=70-15 / ATCC MYA-4617 / FGSC 8958;
RX   PubMed=15846337; DOI=10.1038/nature03449;
RA   Dean R.A., Talbot N.J., Ebbole D.J., Farman M.L., Mitchell T.K.,
RA   Orbach M.J., Thon M.R., Kulkarni R., Xu J.-R., Pan H., Read N.D.,
RA   Lee Y.-H., Carbone I., Brown D., Oh Y.Y., Donofrio N., Jeong J.S.,
RA   Soanes D.M., Djonovic S., Kolomiets E., Rehmeyer C., Li W., Harding M.,
RA   Kim S., Lebrun M.-H., Bohnert H., Coughlan S., Butler J., Calvo S.E.,
RA   Ma L.-J., Nicol R., Purcell S., Nusbaum C., Galagan J.E., Birren B.W.;
RT   "The genome sequence of the rice blast fungus Magnaporthe grisea.";
RL   Nature 434:980-986(2005).
CC   -!- FUNCTION: Catalyzes the intermembrane transfer of phosphatidylglycerol
CC       and phosphatidylinositol. {ECO:0000250}.
CC   -!- SUBUNIT: Monomer. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the NPC2 family. {ECO:0000305}.
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DR   EMBL; CM001232; EHA54725.1; -; Genomic_DNA.
DR   RefSeq; XP_003714532.1; XM_003714484.1.
DR   AlphaFoldDB; Q52FS9; -.
DR   SMR; Q52FS9; -.
DR   STRING; 318829.MGG_01557T0; -.
DR   EnsemblFungi; MGG_01557T0; MGG_01557T0; MGG_01557.
DR   GeneID; 2679503; -.
DR   KEGG; mgr:MGG_01557; -.
DR   VEuPathDB; FungiDB:MGG_01557; -.
DR   eggNOG; KOG4680; Eukaryota.
DR   HOGENOM; CLU_097982_0_0_1; -.
DR   InParanoid; Q52FS9; -.
DR   OMA; QTYDLCE; -.
DR   OrthoDB; 1548356at2759; -.
DR   Proteomes; UP000009058; Chromosome 2.
DR   GO; GO:0000328; C:fungal-type vacuole lumen; IEA:EnsemblFungi.
DR   GO; GO:0032934; F:sterol binding; IEA:EnsemblFungi.
DR   GO; GO:0032366; P:intracellular sterol transport; IEA:EnsemblFungi.
DR   CDD; cd00917; PG-PI_TP; 1.
DR   InterPro; IPR014756; Ig_E-set.
DR   InterPro; IPR003172; ML_dom.
DR   InterPro; IPR033917; ML_PG-PI_TP.
DR   InterPro; IPR039670; NPC2-like.
DR   PANTHER; PTHR11306; PTHR11306; 1.
DR   Pfam; PF02221; E1_DerP2_DerF2; 1.
DR   SMART; SM00737; ML; 1.
DR   SUPFAM; SSF81296; SSF81296; 1.
PE   3: Inferred from homology;
KW   Lipid transport; Reference proteome; Signal; Transport.
FT   SIGNAL          1..18
FT                   /evidence="ECO:0000255"
FT   PROPEP          19..32
FT                   /evidence="ECO:0000250"
FT                   /id="PRO_0000019887"
FT   CHAIN           33..178
FT                   /note="Phosphatidylglycerol/phosphatidylinositol transfer
FT                   protein"
FT                   /id="PRO_0000019888"
SQ   SEQUENCE   178 AA;  19555 MW;  1DE089186333AB38 CRC64;
     MRFSTAFLAL LSVGFSSARL QGRDQVPVAL DDDHKIPGES PLKLCDGDHK DDILKITKVD
     LSPNPPKAGE SLVIKASGDV TQKIEEGAYI NLSVKYGLIR LINTKADLCE QIKNVDLECP
     IDEGKLDIVK SVDLPNEIPP GKYTVFADVY TKDNKKISCL TAEVRFERNS IATPWGDL