ID   NPF_CORAP               Reviewed;          39 AA.
AC   P41321;
DT   01-FEB-1995, integrated into UniProtKB/Swiss-Prot.
DT   01-FEB-1995, sequence version 1.
DT   25-MAY-2022, entry version 61.
DE   RecName: Full=Neuropeptide F;
DE            Short=NPF;
OS   Cornu aspersum (Brown garden snail) (Helix aspersa).
OC   Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Mollusca; Gastropoda;
OC   Heterobranchia; Euthyneura; Panpulmonata; Eupulmonata; Stylommatophora;
OC   Helicina; Helicoidea; Helicidae; Cornu; Cornu.
OX   NCBI_TaxID=6535;
RN   [1]
RP   PROTEIN SEQUENCE, AND AMIDATION AT PHE-39.
RC   TISSUE=Circumesophageal ganglion;
RX   PubMed=1472263; DOI=10.1016/0167-0115(92)90515-v;
RA   Leung P.S., Shaw C., Maule A.G., Thim L., Johnston C.F., Irvine G.B.;
RT   "The primary structure of neuropeptide F (NPF) from the garden snail, Helix
RT   aspersa.";
RL   Regul. Pept. 41:71-81(1992).
CC   -!- FUNCTION: May have an important physiological role in neuroregulation.
CC   -!- SUBCELLULAR LOCATION: Secreted.
CC   -!- TISSUE SPECIFICITY: Neuronal somata and fibers.
CC   -!- SIMILARITY: Belongs to the NPY family. {ECO:0000305}.
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DR   PIR; A48544; A48544.
DR   AlphaFoldDB; P41321; -.
DR   SMR; P41321; -.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0005179; F:hormone activity; IEA:InterPro.
DR   GO; GO:0007218; P:neuropeptide signaling pathway; IEA:UniProtKB-KW.
DR   CDD; cd00126; PAH; 1.
DR   InterPro; IPR001955; Pancreatic_hormone-like.
DR   InterPro; IPR020392; Pancreatic_hormone-like_CS.
DR   Pfam; PF00159; Hormone_3; 1.
DR   SMART; SM00309; PAH; 1.
DR   PROSITE; PS00265; PANCREATIC_HORMONE_1; 1.
DR   PROSITE; PS50276; PANCREATIC_HORMONE_2; 1.
PE   1: Evidence at protein level;
KW   Amidation; Direct protein sequencing; Neuropeptide; Secreted.
FT   PEPTIDE         1..39
FT                   /note="Neuropeptide F"
FT                   /id="PRO_0000044824"
FT   MOD_RES         39
FT                   /note="Phenylalanine amide"
FT                   /evidence="ECO:0000269|PubMed:1472263"
SQ   SEQUENCE   39 AA;  4856 MW;  4B54AA7414CAAE33 CRC64;
     STQMLSPPER PREFRHPNEL RQYLKELNEY YAIMGRTRF