ID   NPF_SCHGR               Reviewed;           9 AA.
AC   P86443;
DT   23-MAR-2010, integrated into UniProtKB/Swiss-Prot.
DT   23-MAR-2010, sequence version 1.
DT   11-DEC-2019, entry version 12.
DE   RecName: Full=Neuropeptide F {ECO:0000303|PubMed:11179815, ECO:0000303|PubMed:19456328, ECO:0000303|PubMed:19524670};
DE            Short=NPF {ECO:0000303|PubMed:11179815};
DE            Short=Scg-NPF {ECO:0000303|PubMed:19524670};
OS   Schistocerca gregaria (Desert locust) (Gryllus gregarius).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Polyneoptera; Orthoptera; Caelifera; Acrididea; Acridomorpha;
OC   Acridoidea; Acrididae; Cyrtacanthacridinae; Schistocerca.
OX   NCBI_TaxID=7010;
RN   [1] {ECO:0000305}
RP   PROTEIN SEQUENCE, AND FUNCTION.
RX   PubMed=11179815; DOI=10.1016/s0196-9781(00)00385-5;
RA   Schoofs L., Clynen E., Cerstiaens A., Baggerman G., Wei Z., Vercammen T.,
RA   Nachman R., De Loof A., Tanaka S.;
RT   "Newly discovered functions for some myotropic neuropeptides in locusts.";
RL   Peptides 22:219-227(2001).
RN   [2] {ECO:0000305}
RP   PROTEIN SEQUENCE, TISSUE SPECIFICITY, MASS SPECTROMETRY, AND AMIDATION AT
RP   PHE-9.
RX   PubMed=19456328; DOI=10.1111/j.1749-6632.2008.03624.x;
RA   Clynen E., Husson S.J., Schoofs L.;
RT   "Identification of new members of the (short) neuropeptide F family in
RT   locusts and Caenorhabditis elegans.";
RL   Ann. N. Y. Acad. Sci. 1163:60-74(2009).
RN   [3] {ECO:0000305}
RP   IDENTIFICATION BY MASS SPECTROMETRY, AND TISSUE SPECIFICITY.
RX   PubMed=19524670; DOI=10.1016/j.ibmb.2009.06.001;
RA   Clynen E., Schoofs L.;
RT   "Peptidomic survey of the locust neuroendocrine system.";
RL   Insect Biochem. Mol. Biol. 39:491-507(2009).
CC   -!- FUNCTION: Accelerates ovarian maturation in females.
CC       {ECO:0000269|PubMed:11179815}.
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000305}.
CC   -!- TISSUE SPECIFICITY: Widely expressed in the nervous system. Expressed
CC       in corpora cardiaca, hypocerebral ganglion, frontal ganglion,
CC       protocerebrum, antennal lobe, tritocerebrum, thoracic ganglia,
CC       esophageal nerves, recurrent nerve and frontal connectives. Not
CC       detected in corpora allata, circumesophageal connectives, subesophageal
CC       ganglion, abdominal ganglion and abdominal perisympathetic organs.
CC       {ECO:0000269|PubMed:19456328, ECO:0000269|PubMed:19524670}.
CC   -!- MASS SPECTROMETRY: Mass=1121.6; Method=MALDI;
CC       Evidence={ECO:0000269|PubMed:19456328};
CC   -!- SIMILARITY: Belongs to the NPY family. {ECO:0000255}.
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DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0007218; P:neuropeptide signaling pathway; IEA:UniProtKB-KW.
PE   1: Evidence at protein level;
KW   Amidation; Direct protein sequencing; Neuropeptide; Secreted.
FT   PEPTIDE         1..9
FT                   /note="Neuropeptide F"
FT                   /evidence="ECO:0000269|PubMed:11179815,
FT                   ECO:0000269|PubMed:19456328"
FT                   /id="PRO_0000392446"
FT   MOD_RES         9
FT                   /note="Phenylalanine amide"
FT                   /evidence="ECO:0000269|PubMed:19456328"
SQ   SEQUENCE   9 AA;  1123 MW;  88A917740DC2D6C5 CRC64;
     YSQVARPRF