NPGR1_ARATH
ID NPGR1_ARATH Reviewed; 694 AA.
AC Q9CB03;
DT 18-JAN-2017, integrated into UniProtKB/Swiss-Prot.
DT 01-JUN-2001, sequence version 1.
DT 03-AUG-2022, entry version 148.
DE RecName: Full=Protein NPGR1 {ECO:0000303|PubMed:12928497};
DE AltName: Full=NO POLLEN GERMINATION RELATED 1 {ECO:0000303|PubMed:12928497};
GN Name=NPGR1 {ECO:0000303|PubMed:12928497};
GN OrderedLocusNames=At1g27460 {ECO:0000312|Araport:AT1G27460};
GN ORFNames=F17L21.25 {ECO:0000312|EMBL:AAF99738.1};
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA], GENE FAMILY, NOMENCLATURE, INTERACTION WITH
RP CALMODULIN, AND TISSUE SPECIFICITY.
RX PubMed=12928497; DOI=10.1073/pnas.1734110100;
RA Golovkin M., Reddy A.;
RT "A calmodulin-binding protein from Arabidopsis has an essential role in
RT pollen germination.";
RL Proc. Natl. Acad. Sci. U.S.A. 100:10558-10563(2003).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130712; DOI=10.1038/35048500;
RA Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O.,
RA Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E.,
RA Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K., Conn L.,
RA Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P.,
RA Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D.,
RA Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J.,
RA Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L.,
RA Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A.,
RA Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A.,
RA Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M.,
RA Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M.,
RA Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P.,
RA Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D.,
RA Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D.,
RA Yu G., Fraser C.M., Venter J.C., Davis R.W.;
RT "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.";
RL Nature 408:816-820(2000).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=14593172; DOI=10.1126/science.1088305;
RA Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA Ecker J.R.;
RT "Empirical analysis of transcriptional activity in the Arabidopsis
RT genome.";
RL Science 302:842-846(2003).
RN [5]
RP INTERACTION WITH CALMODULIN.
RX PubMed=11782485; DOI=10.1074/jbc.m111626200;
RA Reddy V.S., Ali G.S., Reddy A.S.N.;
RT "Genes encoding calmodulin-binding proteins in the Arabidopsis genome.";
RL J. Biol. Chem. 277:9840-9852(2002).
CC -!- SUBUNIT: Interacts with calmodulin in a calcium-dependent manner.
CC {ECO:0000269|PubMed:11782485, ECO:0000269|PubMed:12928497}.
CC -!- TISSUE SPECIFICITY: Expressed in pollen, flowers, fruits and leaves.
CC {ECO:0000269|PubMed:12928497}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AC004557; AAF99738.1; -; Genomic_DNA.
DR EMBL; CP002684; AEE30834.1; -; Genomic_DNA.
DR EMBL; AF428415; AAL16183.1; -; mRNA.
DR EMBL; BT010131; AAQ22600.1; -; mRNA.
DR RefSeq; NP_564285.1; NM_102510.2.
DR AlphaFoldDB; Q9CB03; -.
DR SMR; Q9CB03; -.
DR STRING; 3702.AT1G27460.1; -.
DR iPTMnet; Q9CB03; -.
DR PaxDb; Q9CB03; -.
DR PRIDE; Q9CB03; -.
DR ProteomicsDB; 250542; -.
DR EnsemblPlants; AT1G27460.1; AT1G27460.1; AT1G27460.
DR GeneID; 839637; -.
DR Gramene; AT1G27460.1; AT1G27460.1; AT1G27460.
DR KEGG; ath:AT1G27460; -.
DR Araport; AT1G27460; -.
DR TAIR; locus:2016029; AT1G27460.
DR eggNOG; KOG4162; Eukaryota.
DR HOGENOM; CLU_024601_0_0_1; -.
DR InParanoid; Q9CB03; -.
DR OMA; PRNEYEE; -.
DR OrthoDB; 167932at2759; -.
DR PhylomeDB; Q9CB03; -.
DR PRO; PR:Q9CB03; -.
DR Proteomes; UP000006548; Chromosome 1.
DR ExpressionAtlas; Q9CB03; baseline and differential.
DR GO; GO:0031234; C:extrinsic component of cytoplasmic side of plasma membrane; IDA:TAIR.
DR GO; GO:0005886; C:plasma membrane; IDA:TAIR.
DR GO; GO:0005516; F:calmodulin binding; TAS:TAIR.
DR Gene3D; 1.25.40.10; -; 2.
DR InterPro; IPR043376; NPG1-like.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR InterPro; IPR019734; TPR_repeat.
DR PANTHER; PTHR44102; PTHR44102; 1.
DR SMART; SM00028; TPR; 6.
DR SUPFAM; SSF48452; SSF48452; 2.
DR PROSITE; PS50293; TPR_REGION; 1.
PE 1: Evidence at protein level;
KW Calmodulin-binding; Reference proteome; Repeat; TPR repeat.
FT CHAIN 1..694
FT /note="Protein NPGR1"
FT /id="PRO_0000438623"
FT REPEAT 32..65
FT /note="TPR 1"
FT /evidence="ECO:0000255"
FT REPEAT 66..101
FT /note="TPR 2"
FT /evidence="ECO:0000255"
FT REPEAT 135..168
FT /note="TPR 3"
FT /evidence="ECO:0000255"
FT REPEAT 188..221
FT /note="TPR 4"
FT /evidence="ECO:0000255"
FT REPEAT 307..340
FT /note="TPR 5"
FT /evidence="ECO:0000255"
FT REPEAT 551..584
FT /note="TPR 6"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00339"
FT REPEAT 585..618
FT /note="TPR 7"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00339"
FT REPEAT 620..654
FT /note="TPR 8"
FT /evidence="ECO:0000255"
FT REPEAT 655..688
FT /note="TPR 9"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00339"
FT REGION 12..40
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 21..37
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 694 AA; 76871 MW; 565D10BDC55DEBD9 CRC64;
MLCACSGEQF RFEDQPGSPE SLATRDFSAS GLSSRNGGGD WDSKLEDIQV DEAESTLKEA
LSLNYEEARA LLGRLEYQRG NFDAALQVFK GIDIKVLTPR IIKAIVEKTL PCKPRSKAVI
VPPTTMSMHS VSLLLEAILL KARSLEELGS YKEAAEECKI ILDVVENALP SGMPDGISGF
AKLQDIFQKA LELLPLLWKK AGNHHETIAS YRRALSRPWN LDPQRLAVTQ KSLALVLLYG
SVEACPKDNI EEAIVLLMLL VKKMVVGDIQ WDPELMDHLT YALSMTGQFE VLANYLEQTL
PGVYTRGERW YLLSLCYSAA GIDKAAINLL KMALGPSESR QIPHIPLLLF GAKLCSKDPK
HSRDGINFAH RLLDLGNSQS EHLLSQAHKF LGVCYGNAAR SSKLDSERVF LQKKSLFSLN
EAAKRGKADP ELDVIFNLSV ENAVQRNVQA ALDGAVEYSS MVGGVSTKGW KHLAIVLSAE
KRLKDAESIL DFTMEEAGDI EKIELLRLKA VLQMAQEQPK KAMKTCSSLL GLIRAQEKSE
QSESLLQKFE TEAWQDLASV YGKLGSWSDA ETCLEKARSM CYYSPRGWNE TGLCLEAKSL
HEEALISFFL SLSIEPDHVP SIVSIAEVMM KSGDESLPTA KSFLMNALRL DPRNHDAWMK
LGHVAKKQGL SQQAAEFYQA AYELELSAPV QSFI
