ID   NPH3_ORYSJ              Reviewed;         762 AA.
AC   Q5KS50; Q0E093; Q6YTG4;
DT   05-JUL-2005, integrated into UniProtKB/Swiss-Prot.
DT   15-FEB-2005, sequence version 1.
DT   03-AUG-2022, entry version 99.
DE   RecName: Full=Coleoptile phototropism protein 1;
DE   AltName: Full=BTB/POZ domain-containing protein CPT1;
DE   AltName: Full=Non-phototropic hypocotyl 3-like protein;
DE            Short=NPH3-like protein;
GN   Name=CPT1; OrderedLocusNames=Os02g0568200, LOC_Os02g35970;
GN   ORFNames=P0020D05.32, P0025F02.3;
OS   Oryza sativa subsp. japonica (Rice).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC   Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX   NCBI_TaxID=39947;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA], AND FUNCTION.
RC   STRAIN=cv. Nihonmasari;
RX   PubMed=15598797; DOI=10.1105/tpc.104.028357;
RA   Haga K., Takano M., Neumann R., Iino M.;
RT   "The rice coleoptile phototropism1 gene encoding an ortholog of Arabidopsis
RT   NPH3 is required for phototropism of coleoptiles and lateral translocation
RT   of auxin.";
RL   Plant Cell 17:103-115(2005).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Nipponbare;
RX   PubMed=16100779; DOI=10.1038/nature03895;
RG   International rice genome sequencing project (IRGSP);
RT   "The map-based sequence of the rice genome.";
RL   Nature 436:793-800(2005).
RN   [3]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Nipponbare;
RX   PubMed=18089549; DOI=10.1093/nar/gkm978;
RG   The rice annotation project (RAP);
RT   "The rice annotation project database (RAP-DB): 2008 update.";
RL   Nucleic Acids Res. 36:D1028-D1033(2008).
RN   [4]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Nipponbare;
RX   PubMed=24280374; DOI=10.1186/1939-8433-6-4;
RA   Kawahara Y., de la Bastide M., Hamilton J.P., Kanamori H., McCombie W.R.,
RA   Ouyang S., Schwartz D.C., Tanaka T., Wu J., Zhou S., Childs K.L.,
RA   Davidson R.M., Lin H., Quesada-Ocampo L., Vaillancourt B., Sakai H.,
RA   Lee S.S., Kim J., Numa H., Itoh T., Buell C.R., Matsumoto T.;
RT   "Improvement of the Oryza sativa Nipponbare reference genome using next
RT   generation sequence and optical map data.";
RL   Rice 6:4-4(2013).
CC   -!- FUNCTION: May act as a substrate-specific adapter of an E3 ubiquitin-
CC       protein ligase complex (CUL3-RBX1-BTB) which mediates the
CC       ubiquitination and subsequent proteasomal degradation of target
CC       proteins (By similarity). Plays a role as signal transduction component
CC       in coleoptile phototropism and lateral translocation of auxin.
CC       {ECO:0000250, ECO:0000269|PubMed:15598797}.
CC   -!- PATHWAY: Protein modification; protein ubiquitination.
CC   -!- DOMAIN: The BTB/POZ domain mediates the interaction with some component
CC       of ubiquitin ligase complexes.
CC   -!- SIMILARITY: Belongs to the NPH3 family. {ECO:0000255|PROSITE-
CC       ProRule:PRU00982}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=BAD17765.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
CC       Sequence=BAD17773.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR   EMBL; AB186127; BAD86496.1; -; mRNA.
DR   EMBL; AP006068; BAD17765.1; ALT_SEQ; Genomic_DNA.
DR   EMBL; AP006069; BAD17773.1; ALT_SEQ; Genomic_DNA.
DR   EMBL; AP008208; BAF09095.1; -; Genomic_DNA.
DR   EMBL; AP014958; BAS79325.1; -; Genomic_DNA.
DR   RefSeq; XP_015624758.1; XM_015769272.1.
DR   AlphaFoldDB; Q5KS50; -.
DR   STRING; 4530.OS02T0568200-00; -.
DR   PaxDb; Q5KS50; -.
DR   PRIDE; Q5KS50; -.
DR   EnsemblPlants; Os02t0568200-00; Os02t0568200-00; Os02g0568200.
DR   GeneID; 4329720; -.
DR   Gramene; Os02t0568200-00; Os02t0568200-00; Os02g0568200.
DR   KEGG; osa:4329720; -.
DR   eggNOG; ENOG502QR3H; Eukaryota.
DR   HOGENOM; CLU_005994_6_2_1; -.
DR   InParanoid; Q5KS50; -.
DR   OMA; AIMHYAS; -.
DR   OrthoDB; 234630at2759; -.
DR   UniPathway; UPA00143; -.
DR   Proteomes; UP000000763; Chromosome 2.
DR   Proteomes; UP000059680; Chromosome 2.
DR   GO; GO:0016567; P:protein ubiquitination; IEA:UniProtKB-UniPathway.
DR   InterPro; IPR029959; NPH3-like.
DR   InterPro; IPR043454; NPH3/RPT2-like.
DR   InterPro; IPR027356; NPH3_dom.
DR   InterPro; IPR011333; SKP1/BTB/POZ_sf.
DR   PANTHER; PTHR32370; PTHR32370; 1.
DR   PANTHER; PTHR32370:SF92; PTHR32370:SF92; 1.
DR   Pfam; PF03000; NPH3; 1.
DR   SUPFAM; SSF54695; SSF54695; 1.
DR   PROSITE; PS51649; NPH3; 1.
PE   2: Evidence at transcript level;
KW   Coiled coil; Reference proteome; Ubl conjugation pathway.
FT   CHAIN           1..762
FT                   /note="Coleoptile phototropism protein 1"
FT                   /id="PRO_0000057940"
FT   DOMAIN          51..128
FT                   /note="BTB"
FT   DOMAIN          268..607
FT                   /note="NPH3"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00982"
FT   REGION          1..29
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          227..264
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          460..495
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          687..718
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          731..762
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          654..691
FT                   /evidence="ECO:0000255"
FT   COMPBIAS        467..481
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        702..718
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   762 AA;  80604 MW;  0EE2851CF30F1F25 CRC64;
     MWESESESHG GERGLVPVGG GGGSGRHEAA LKNDGFVRRD RSWYVNSDIP SDLLVKVGDV
     NFYLHKYPMI SRSGRMSRAV YESSAADEAE ADAAAAVAVV EMGDLPGGAG SFELAARFSY
     GMAVDLTAAN ISGLRCAAEY LEMTEEMEEG NLIFKTEAFL SYVVLSSWRD SIAVLKSCEA
     LSPWAENLQI VRRCSESIAW KACANPRGVR WAYTGAGAGS GGARGGPAAI RGGGGSGGTA
     SPRWNVGGGG GGESKESSPS RQAVPPADWW FEDVSVLRID HFVRVVTAIK VKGMRFDLIG
     AAITHYASKW LPGLTKDAPL GATHDEPWAQ ASAAGVGGGG LHMMIISGAG GGKDDVLAAC
     SAPSREQRMV VESIISITPP QRDSVSCGFL LRLLRLAIML RAAPALVTEL EKRVGMQLEQ
     AALADLLIPS YGGRAADTAY DVDLVQRLVE HFLVQEQTEM AVASSPGRGD PPPPPQPEYY
     SGRMPPSSAA AASASASTGG LNAKARVARL LDSYLSEVSR DRNLSLTKFQ VLAESLPESA
     RACDDGLYRA VDSYLKAHPT LTEHERKRLC RVMDCQKLSF DACMHAAQNE RLPLRVVVQV
     LFTEQVKISN ALASSSAALR SSSSAPGADA APAMPTTRRQ LLDGTPQSFQ EGWAAAKKDI
     NTLKFELESM KAKYLELQHE MDALQKQVDG RGGGAPSPAA AKIGKQQQQG TSASAWSSGW
     KKLGRLAKMS GADAAAGGGV APPGGGEAAA RKGPRRWRNS IS