ID   NPIA3_HUMAN             Reviewed;         350 AA.
AC   F8WFD2;
DT   16-OCT-2013, integrated into UniProtKB/Swiss-Prot.
DT   21-SEP-2011, sequence version 1.
DT   03-AUG-2022, entry version 67.
DE   RecName: Full=Nuclear pore complex-interacting protein family member A3;
GN   Name=NPIPA3;
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC   Homo.
OX   NCBI_TaxID=9606;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=15616553; DOI=10.1038/nature03187;
RA   Martin J., Han C., Gordon L.A., Terry A., Prabhakar S., She X., Xie G.,
RA   Hellsten U., Chan Y.M., Altherr M., Couronne O., Aerts A., Bajorek E.,
RA   Black S., Blumer H., Branscomb E., Brown N.C., Bruno W.J., Buckingham J.M.,
RA   Callen D.F., Campbell C.S., Campbell M.L., Campbell E.W., Caoile C.,
RA   Challacombe J.F., Chasteen L.A., Chertkov O., Chi H.C., Christensen M.,
RA   Clark L.M., Cohn J.D., Denys M., Detter J.C., Dickson M.,
RA   Dimitrijevic-Bussod M., Escobar J., Fawcett J.J., Flowers D., Fotopulos D.,
RA   Glavina T., Gomez M., Gonzales E., Goodstein D., Goodwin L.A., Grady D.L.,
RA   Grigoriev I., Groza M., Hammon N., Hawkins T., Haydu L., Hildebrand C.E.,
RA   Huang W., Israni S., Jett J., Jewett P.B., Kadner K., Kimball H.,
RA   Kobayashi A., Krawczyk M.-C., Leyba T., Longmire J.L., Lopez F., Lou Y.,
RA   Lowry S., Ludeman T., Manohar C.F., Mark G.A., McMurray K.L., Meincke L.J.,
RA   Morgan J., Moyzis R.K., Mundt M.O., Munk A.C., Nandkeshwar R.D.,
RA   Pitluck S., Pollard M., Predki P., Parson-Quintana B., Ramirez L., Rash S.,
RA   Retterer J., Ricke D.O., Robinson D.L., Rodriguez A., Salamov A.,
RA   Saunders E.H., Scott D., Shough T., Stallings R.L., Stalvey M.,
RA   Sutherland R.D., Tapia R., Tesmer J.G., Thayer N., Thompson L.S., Tice H.,
RA   Torney D.C., Tran-Gyamfi M., Tsai M., Ulanovsky L.E., Ustaszewska A.,
RA   Vo N., White P.S., Williams A.L., Wills P.L., Wu J.-R., Wu K., Yang J.,
RA   DeJong P., Bruce D., Doggett N.A., Deaven L., Schmutz J., Grimwood J.,
RA   Richardson P., Rokhsar D.S., Eichler E.E., Gilna P., Lucas S.M.,
RA   Myers R.M., Rubin E.M., Pennacchio L.A.;
RT   "The sequence and analysis of duplication-rich human chromosome 16.";
RL   Nature 432:988-994(2004).
CC   -!- SIMILARITY: Belongs to the NPIP family. {ECO:0000305}.
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DR   EMBL; AC009167; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AC136443; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   CCDS; CCDS59262.1; -.
DR   RefSeq; NP_001264252.1; NM_001277323.1.
DR   RefSeq; XP_005255541.1; XM_005255484.3.
DR   AlphaFoldDB; F8WFD2; -.
DR   SMR; F8WFD2; -.
DR   IntAct; F8WFD2; 1.
DR   STRING; 9606.ENSP00000446882; -.
DR   iPTMnet; F8WFD2; -.
DR   PhosphoSitePlus; F8WFD2; -.
DR   BioMuta; NPIPA3; -.
DR   MassIVE; F8WFD2; -.
DR   PeptideAtlas; F8WFD2; -.
DR   PRIDE; F8WFD2; -.
DR   Antibodypedia; 77232; 2 antibodies from 2 providers.
DR   Ensembl; ENST00000552140.5; ENSP00000448841.1; ENSG00000224712.12.
DR   GeneID; 642778; -.
DR   KEGG; hsa:642778; -.
DR   UCSC; uc002dcr.5; human.
DR   CTD; 642778; -.
DR   GeneCards; NPIPA3; -.
DR   HGNC; HGNC:41978; NPIPA3.
DR   HPA; ENSG00000224712; Low tissue specificity.
DR   neXtProt; NX_F8WFD2; -.
DR   VEuPathDB; HostDB:ENSG00000224712; -.
DR   eggNOG; ENOG502R1NR; Eukaryota.
DR   GeneTree; ENSGT00540000072033; -.
DR   OrthoDB; 119185at2759; -.
DR   PathwayCommons; F8WFD2; -.
DR   BioGRID-ORCS; 642778; 26 hits in 166 CRISPR screens.
DR   ChiTaRS; NPIPA3; human.
DR   GenomeRNAi; 642778; -.
DR   Pharos; F8WFD2; Tdark.
DR   PRO; PR:F8WFD2; -.
DR   Proteomes; UP000005640; Chromosome 16.
DR   RNAct; F8WFD2; protein.
DR   Bgee; ENSG00000224712; Expressed in cerebellum and 98 other tissues.
DR   ExpressionAtlas; F8WFD2; baseline and differential.
DR   Genevisible; F8WFD2; HS.
DR   GO; GO:0005654; C:nucleoplasm; IDA:HPA.
DR   InterPro; IPR009443; NPIP.
DR   PANTHER; PTHR15438; PTHR15438; 1.
DR   Pfam; PF06409; NPIP; 2.
PE   3: Inferred from homology;
KW   Reference proteome.
FT   CHAIN           1..350
FT                   /note="Nuclear pore complex-interacting protein family
FT                   member A3"
FT                   /id="PRO_0000423917"
FT   REGION          306..325
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        311..325
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   350 AA;  40061 MW;  2FC812057818B444 CRC64;
     MFCCLGYEWL SGGCKTWHSA WVINTLADHR HRGTDFGGSP WLLIITVFLR SYKFAISLCT
     SYLCVSFLKT IFPSQNGHDG STDVQQRARR SNRRRQEGIK IVLEDIFTLW RQVETKVRAK
     ICKMKVTTKV NRHDKINGKR KTAKEHLRKL SMKEREHGEK ERQVSEAEEN GKLDMKEIHT
     YMEMFQRAQA LRRRAEDYYR CKITPSARKP LCNRVRMAAA EHRHSSGLPY WPYLTAETLK
     NRMGHQPPPP TQQHSIIDNS LSLKTPPECL LTPLPPSALP SADDNLKTPA ECLLYPLPPS
     ADDNLKTPPE CLLTPLPPSA PPSVDDNLKT PPKCVCSLPF HPQRMIISRN