ID   NPIA8_HUMAN             Reviewed;         369 AA.
AC   P0DM63;
DT   16-OCT-2013, integrated into UniProtKB/Swiss-Prot.
DT   16-OCT-2013, sequence version 1.
DT   03-AUG-2022, entry version 50.
DE   RecName: Full=Nuclear pore complex-interacting protein family member A8;
GN   Name=NPIPA8;
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC   Homo.
OX   NCBI_TaxID=9606;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=15616553; DOI=10.1038/nature03187;
RA   Martin J., Han C., Gordon L.A., Terry A., Prabhakar S., She X., Xie G.,
RA   Hellsten U., Chan Y.M., Altherr M., Couronne O., Aerts A., Bajorek E.,
RA   Black S., Blumer H., Branscomb E., Brown N.C., Bruno W.J., Buckingham J.M.,
RA   Callen D.F., Campbell C.S., Campbell M.L., Campbell E.W., Caoile C.,
RA   Challacombe J.F., Chasteen L.A., Chertkov O., Chi H.C., Christensen M.,
RA   Clark L.M., Cohn J.D., Denys M., Detter J.C., Dickson M.,
RA   Dimitrijevic-Bussod M., Escobar J., Fawcett J.J., Flowers D., Fotopulos D.,
RA   Glavina T., Gomez M., Gonzales E., Goodstein D., Goodwin L.A., Grady D.L.,
RA   Grigoriev I., Groza M., Hammon N., Hawkins T., Haydu L., Hildebrand C.E.,
RA   Huang W., Israni S., Jett J., Jewett P.B., Kadner K., Kimball H.,
RA   Kobayashi A., Krawczyk M.-C., Leyba T., Longmire J.L., Lopez F., Lou Y.,
RA   Lowry S., Ludeman T., Manohar C.F., Mark G.A., McMurray K.L., Meincke L.J.,
RA   Morgan J., Moyzis R.K., Mundt M.O., Munk A.C., Nandkeshwar R.D.,
RA   Pitluck S., Pollard M., Predki P., Parson-Quintana B., Ramirez L., Rash S.,
RA   Retterer J., Ricke D.O., Robinson D.L., Rodriguez A., Salamov A.,
RA   Saunders E.H., Scott D., Shough T., Stallings R.L., Stalvey M.,
RA   Sutherland R.D., Tapia R., Tesmer J.G., Thayer N., Thompson L.S., Tice H.,
RA   Torney D.C., Tran-Gyamfi M., Tsai M., Ulanovsky L.E., Ustaszewska A.,
RA   Vo N., White P.S., Williams A.L., Wills P.L., Wu J.-R., Wu K., Yang J.,
RA   DeJong P., Bruce D., Doggett N.A., Deaven L., Schmutz J., Grimwood J.,
RA   Richardson P., Rokhsar D.S., Eichler E.E., Gilna P., Lucas S.M.,
RA   Myers R.M., Rubin E.M., Pennacchio L.A.;
RT   "The sequence and analysis of duplication-rich human chromosome 16.";
RL   Nature 432:988-994(2004).
CC   -!- SIMILARITY: Belongs to the NPIP family. {ECO:0000305}.
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DR   EMBL; AC126755; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   CCDS; CCDS61865.1; -.
DR   RefSeq; NP_001269436.1; NM_001282507.1.
DR   RefSeq; NP_001269440.1; NM_001282511.1.
DR   RefSeq; XP_016878323.1; XM_017022834.1.
DR   RefSeq; XP_016878324.1; XM_017022835.1.
DR   RefSeq; XP_016878331.1; XM_017022842.1.
DR   RefSeq; XP_016878332.1; XM_017022843.1.
DR   AlphaFoldDB; P0DM63; -.
DR   SMR; P0DM63; -.
DR   iPTMnet; P0DM63; -.
DR   PhosphoSitePlus; P0DM63; -.
DR   BioMuta; NPIPA8; -.
DR   DMDM; 550540853; -.
DR   jPOST; P0DM63; -.
DR   MassIVE; P0DM63; -.
DR   PRIDE; P0DM63; -.
DR   DNASU; 101059938; -.
DR   Ensembl; ENST00000525596.5; ENSP00000435325.1; ENSG00000214940.8.
DR   Ensembl; ENST00000541810.5; ENSP00000438887.2; ENSG00000214940.8.
DR   GeneID; 101059938; -.
DR   GeneID; 101059953; -.
DR   KEGG; hsa:101059938; -.
DR   KEGG; hsa:101059953; -.
DR   MANE-Select; ENST00000525596.6; ENSP00000435325.1; NM_001282511.3; NP_001269440.1.
DR   MANE-Select; ENST00000530217.3; ENSP00000431814.2; NM_001282507.2; NP_001269436.1.
DR   UCSC; uc010vag.3; human.
DR   CTD; 101059938; -.
DR   CTD; 101059953; -.
DR   GeneCards; NPIPA8; -.
DR   HGNC; HGNC:41983; NPIPA8.
DR   HPA; ENSG00000214940; Low tissue specificity.
DR   neXtProt; NX_P0DM63; -.
DR   OpenTargets; ENSG00000214940; -.
DR   OpenTargets; ENSG00000214967; -.
DR   VEuPathDB; HostDB:ENSG00000214940; -.
DR   GeneTree; ENSGT00540000072033; -.
DR   HOGENOM; CLU_059939_0_0_1; -.
DR   OrthoDB; 119185at2759; -.
DR   PhylomeDB; P0DM63; -.
DR   PathwayCommons; P0DM63; -.
DR   SignaLink; P0DM63; -.
DR   BioGRID-ORCS; 101059938; 18 hits in 486 CRISPR screens.
DR   BioGRID-ORCS; 101059953; 27 hits in 170 CRISPR screens.
DR   Pharos; P0DM63; Tdark.
DR   PRO; PR:P0DM63; -.
DR   Proteomes; UP000005640; Chromosome 16.
DR   RNAct; P0DM63; protein.
DR   Bgee; ENSG00000214940; Expressed in apex of heart and 89 other tissues.
DR   ExpressionAtlas; P0DM63; baseline.
DR   Genevisible; P0DM63; HS.
DR   GO; GO:0005654; C:nucleoplasm; IDA:HPA.
DR   InterPro; IPR009443; NPIP.
DR   PANTHER; PTHR15438; PTHR15438; 2.
DR   Pfam; PF06409; NPIP; 3.
PE   3: Inferred from homology;
KW   Reference proteome.
FT   CHAIN           1..369
FT                   /note="Nuclear pore complex-interacting protein family
FT                   member A8"
FT                   /id="PRO_0000423919"
FT   REGION          151..171
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   369 AA;  42230 MW;  2046ED0883FA82B2 CRC64;
     MFCCLGYEWL SGGCTTWHSA WVINTLADHR HRGTDFGGSP WLLIITVFLR SYKFAISLCT
     SYLCVSFLKT IFPSQNGHDG STDVQQRARR SNRRRQEGIK IVLEDIFTLW RQVETKVRAK
     IRKMKVTTKV NRHDKINGKR KTAKEHLRKL SMKEREHREE ERQVSEAEEN GKLDMKEIHT
     YMEMFQRAQA LRRRAEDYYR CKITPSARKP LCNRVRMAAV EHRHSSGLPY WPYLTAETLK
     NRMGHQPPPP TQQHSIIDNS LSLKTPSECV LYPLPPSADD NLKTPPECLL TPLPPSALPS
     ADDNLKTPAE CLLYPLPPSA DDNLKTPPEC LLTPLPPSAP PSADDNLKTP PECVCSLPFH
     PQRMIISRN