ID   NPIB2_HUMAN             Reviewed;         397 AA.
AC   A6NJ64; A0A0A6YYH2; J3KPX4;
DT   10-JUN-2008, integrated into UniProtKB/Swiss-Prot.
DT   16-OCT-2013, sequence version 4.
DT   03-AUG-2022, entry version 88.
DE   RecName: Full=Putative nuclear pore complex-interacting protein family member B2 {ECO:0000305};
GN   Name=NPIPB2 {ECO:0000312|HGNC:HGNC:37451};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC   Homo.
OX   NCBI_TaxID=9606;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=15616553; DOI=10.1038/nature03187;
RA   Martin J., Han C., Gordon L.A., Terry A., Prabhakar S., She X., Xie G.,
RA   Hellsten U., Chan Y.M., Altherr M., Couronne O., Aerts A., Bajorek E.,
RA   Black S., Blumer H., Branscomb E., Brown N.C., Bruno W.J., Buckingham J.M.,
RA   Callen D.F., Campbell C.S., Campbell M.L., Campbell E.W., Caoile C.,
RA   Challacombe J.F., Chasteen L.A., Chertkov O., Chi H.C., Christensen M.,
RA   Clark L.M., Cohn J.D., Denys M., Detter J.C., Dickson M.,
RA   Dimitrijevic-Bussod M., Escobar J., Fawcett J.J., Flowers D., Fotopulos D.,
RA   Glavina T., Gomez M., Gonzales E., Goodstein D., Goodwin L.A., Grady D.L.,
RA   Grigoriev I., Groza M., Hammon N., Hawkins T., Haydu L., Hildebrand C.E.,
RA   Huang W., Israni S., Jett J., Jewett P.B., Kadner K., Kimball H.,
RA   Kobayashi A., Krawczyk M.-C., Leyba T., Longmire J.L., Lopez F., Lou Y.,
RA   Lowry S., Ludeman T., Manohar C.F., Mark G.A., McMurray K.L., Meincke L.J.,
RA   Morgan J., Moyzis R.K., Mundt M.O., Munk A.C., Nandkeshwar R.D.,
RA   Pitluck S., Pollard M., Predki P., Parson-Quintana B., Ramirez L., Rash S.,
RA   Retterer J., Ricke D.O., Robinson D.L., Rodriguez A., Salamov A.,
RA   Saunders E.H., Scott D., Shough T., Stallings R.L., Stalvey M.,
RA   Sutherland R.D., Tapia R., Tesmer J.G., Thayer N., Thompson L.S., Tice H.,
RA   Torney D.C., Tran-Gyamfi M., Tsai M., Ulanovsky L.E., Ustaszewska A.,
RA   Vo N., White P.S., Williams A.L., Wills P.L., Wu J.-R., Wu K., Yang J.,
RA   DeJong P., Bruce D., Doggett N.A., Deaven L., Schmutz J., Grimwood J.,
RA   Richardson P., Rokhsar D.S., Eichler E.E., Gilna P., Lucas S.M.,
RA   Myers R.M., Rubin E.M., Pennacchio L.A.;
RT   "The sequence and analysis of duplication-rich human chromosome 16.";
RL   Nature 432:988-994(2004).
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the NPIP family. {ECO:0000305}.
CC   -!- CAUTION: Could be the product of a pseudogene. {ECO:0000305}.
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DR   EMBL; AC007216; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   AlphaFoldDB; A6NJ64; -.
DR   SMR; A6NJ64; -.
DR   iPTMnet; A6NJ64; -.
DR   PhosphoSitePlus; A6NJ64; -.
DR   BioMuta; -; -.
DR   BioMuta; ENSG00000234719; -.
DR   MassIVE; A6NJ64; -.
DR   PaxDb; A6NJ64; -.
DR   PeptideAtlas; A6NJ64; -.
DR   PRIDE; A6NJ64; -.
DR   Ensembl; ENST00000399147.8; ENSP00000382101.4; ENSG00000234719.9.
DR   MANE-Select; ENST00000399147.8; ENSP00000382101.4; NM_001396485.1; NP_001383414.1.
DR   UCSC; uc059qyb.1; human.
DR   GeneCards; NPIPB2; -.
DR   HGNC; HGNC:37451; NPIPB2.
DR   HPA; ENSG00000234719; Tissue enhanced (testis).
DR   neXtProt; NX_A6NJ64; -.
DR   VEuPathDB; HostDB:ENSG00000234719; -.
DR   GeneTree; ENSGT00540000072033; -.
DR   PhylomeDB; A6NJ64; -.
DR   TreeFam; TF333389; -.
DR   Pharos; A6NJ64; Tdark.
DR   Proteomes; UP000005640; Chromosome 16.
DR   RNAct; A6NJ64; protein.
DR   Bgee; ENSG00000234719; Expressed in cerebellar vermis and 98 other tissues.
DR   ExpressionAtlas; A6NJ64; baseline and differential.
DR   GO; GO:0005654; C:nucleoplasm; IDA:HPA.
DR   InterPro; IPR009443; NPIP.
DR   PANTHER; PTHR15438; PTHR15438; 2.
DR   Pfam; PF06409; NPIP; 2.
PE   5: Uncertain;
KW   Nucleus; Reference proteome.
FT   CHAIN           1..397
FT                   /note="Putative nuclear pore complex-interacting protein
FT                   family member B2"
FT                   /id="PRO_0000340269"
FT   REGION          256..397
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        260..281
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        303..317
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        332..385
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   397 AA;  45575 MW;  113DFAAA46851CB5 CRC64;
     MFCCLGYEWL SGGCKTWHSA WVINTLADHH HRGTDFGGSP WLRIIIAFPR SYKVVLTLWT
     VYLWLSFLKT IFQSENGHDV STDVQQRARR SNRRRQEGLR SICMHTKKRV SSFPGNKIGL
     KDVITLRRHV ETKGRAKIRK MKVTTKINHH DKINGKRKTA KKQKLSVKEC EHAEKERQVS
     EAEENGKLDM KEIHTYMKMF QRAQELRRRA EDYHKCKIPP SARKALCNWV RMAAAEHRHS
     SGLPYWPYLT AETLKNRMGH QPPPPTQQHS ITDNSLSLKT PPECLLTPLP PSADDNLKTP
     PECLLTPLPP SAPPSADDNL KTPPLATQEA EAEKPPKPKR WRAAEMESPP EPKRRRAAEV
     ESPPEPKRRR AAEVEPSSPE PKRRRLSKLR TGHCTQA