ID   NPIB6_HUMAN             Reviewed;         425 AA.
AC   E9PJ23;
DT   16-OCT-2013, integrated into UniProtKB/Swiss-Prot.
DT   05-APR-2011, sequence version 1.
DT   03-AUG-2022, entry version 62.
DE   RecName: Full=Nuclear pore complex-interacting protein family member B6;
GN   Name=NPIPB6;
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC   Homo.
OX   NCBI_TaxID=9606;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=15616553; DOI=10.1038/nature03187;
RA   Martin J., Han C., Gordon L.A., Terry A., Prabhakar S., She X., Xie G.,
RA   Hellsten U., Chan Y.M., Altherr M., Couronne O., Aerts A., Bajorek E.,
RA   Black S., Blumer H., Branscomb E., Brown N.C., Bruno W.J., Buckingham J.M.,
RA   Callen D.F., Campbell C.S., Campbell M.L., Campbell E.W., Caoile C.,
RA   Challacombe J.F., Chasteen L.A., Chertkov O., Chi H.C., Christensen M.,
RA   Clark L.M., Cohn J.D., Denys M., Detter J.C., Dickson M.,
RA   Dimitrijevic-Bussod M., Escobar J., Fawcett J.J., Flowers D., Fotopulos D.,
RA   Glavina T., Gomez M., Gonzales E., Goodstein D., Goodwin L.A., Grady D.L.,
RA   Grigoriev I., Groza M., Hammon N., Hawkins T., Haydu L., Hildebrand C.E.,
RA   Huang W., Israni S., Jett J., Jewett P.B., Kadner K., Kimball H.,
RA   Kobayashi A., Krawczyk M.-C., Leyba T., Longmire J.L., Lopez F., Lou Y.,
RA   Lowry S., Ludeman T., Manohar C.F., Mark G.A., McMurray K.L., Meincke L.J.,
RA   Morgan J., Moyzis R.K., Mundt M.O., Munk A.C., Nandkeshwar R.D.,
RA   Pitluck S., Pollard M., Predki P., Parson-Quintana B., Ramirez L., Rash S.,
RA   Retterer J., Ricke D.O., Robinson D.L., Rodriguez A., Salamov A.,
RA   Saunders E.H., Scott D., Shough T., Stallings R.L., Stalvey M.,
RA   Sutherland R.D., Tapia R., Tesmer J.G., Thayer N., Thompson L.S., Tice H.,
RA   Torney D.C., Tran-Gyamfi M., Tsai M., Ulanovsky L.E., Ustaszewska A.,
RA   Vo N., White P.S., Williams A.L., Wills P.L., Wu J.-R., Wu K., Yang J.,
RA   DeJong P., Bruce D., Doggett N.A., Deaven L., Schmutz J., Grimwood J.,
RA   Richardson P., Rokhsar D.S., Eichler E.E., Gilna P., Lucas S.M.,
RA   Myers R.M., Rubin E.M., Pennacchio L.A.;
RT   "The sequence and analysis of duplication-rich human chromosome 16.";
RL   Nature 432:988-994(2004).
CC   -!- SIMILARITY: Belongs to the NPIP family. {ECO:0000305}.
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DR   EMBL; AC138894; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AC138904; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   CCDS; CCDS61892.1; -.
DR   RefSeq; NP_001269453.1; NM_001282524.1.
DR   RefSeq; XP_011544231.1; XM_011545929.2.
DR   AlphaFoldDB; E9PJ23; -.
DR   BioGRID; 609159; 16.
DR   STRING; 9606.ENSP00000431871; -.
DR   BioMuta; NPIPB6; -.
DR   MassIVE; E9PJ23; -.
DR   PaxDb; E9PJ23; -.
DR   PeptideAtlas; E9PJ23; -.
DR   PRIDE; E9PJ23; -.
DR   DNASU; 728741; -.
DR   Ensembl; ENST00000532254.1; ENSP00000431871.1; ENSG00000198156.10.
DR   GeneID; 728741; -.
DR   KEGG; hsa:728741; -.
DR   UCSC; uc010vcr.4; human.
DR   CTD; 728741; -.
DR   GeneCards; NPIPB6; -.
DR   HGNC; HGNC:37454; NPIPB6.
DR   HPA; ENSG00000198156; Tissue enriched (testis).
DR   neXtProt; NX_E9PJ23; -.
DR   OpenTargets; ENSG00000198156; -.
DR   VEuPathDB; HostDB:ENSG00000198156; -.
DR   eggNOG; ENOG502TDBV; Eukaryota.
DR   GeneTree; ENSGT00540000072033; -.
DR   HOGENOM; CLU_059939_0_0_1; -.
DR   InParanoid; E9PJ23; -.
DR   OrthoDB; 1680677at2759; -.
DR   PhylomeDB; E9PJ23; -.
DR   TreeFam; TF333389; -.
DR   PathwayCommons; E9PJ23; -.
DR   SignaLink; E9PJ23; -.
DR   BioGRID-ORCS; 728741; 83 hits in 521 CRISPR screens.
DR   ChiTaRS; NPIPB6; human.
DR   GenomeRNAi; 728741; -.
DR   Pharos; E9PJ23; Tdark.
DR   PRO; PR:E9PJ23; -.
DR   Proteomes; UP000005640; Chromosome 16.
DR   RNAct; E9PJ23; protein.
DR   Bgee; ENSG00000198156; Expressed in left testis and 94 other tissues.
DR   ExpressionAtlas; E9PJ23; baseline and differential.
DR   Genevisible; E9PJ23; HS.
DR   GO; GO:0005654; C:nucleoplasm; IDA:HPA.
DR   InterPro; IPR009443; NPIP.
DR   PANTHER; PTHR15438; PTHR15438; 2.
DR   Pfam; PF06409; NPIP; 2.
PE   3: Inferred from homology;
KW   Reference proteome.
FT   CHAIN           1..425
FT                   /note="Nuclear pore complex-interacting protein family
FT                   member B6"
FT                   /id="PRO_0000423921"
FT   REGION          332..414
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        354..402
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   425 AA;  49162 MW;  6FF21B299D4F7E29 CRC64;
     MVKLSIVLTP QFLSHDQSQL TKELQQHVKS VTCPCEYLRK VINSLAVYRH RETDFGVGVR
     DHPGQHGKTP SPQKLDNLII IIIGFLRRYT FNILFCTSCL CVSFLKTIFW SRNGHDGSMD
     VQQRAWRSNR SRQKGLRSIC MHTKKRVSSF RGNKIGLKDV ITLRRHVETK VRAKIRKRKV
     TTKINRHDKI NGKRKTARKQ KMFQRAQELR RRAEDYHKCK IPPSARKPLC NWVRMVAAEH
     RHSSGLPYWP YLTAETLKNR MGRQPPPPTQ QHSITDNSLS LKTPTECLLT PLPPSVDDNI
     KECPLAPLPP SPLPPSVDDN LKECLFVPLP PSPLPPSVDD NLKTPPLATQ EAEVEKPPKP
     KRWRVDEVEQ SPKPKRRRVD EVEQSPKPKR QREAEAQQLP KPKRRRLSKL RTRHCTQAWA
     IRINP