NPLP1_CAMFO
ID NPLP1_CAMFO Reviewed; 588 AA.
AC E1ZXU8;
DT 14-OCT-2015, integrated into UniProtKB/Swiss-Prot.
DT 30-NOV-2010, sequence version 1.
DT 25-MAY-2022, entry version 21.
DE RecName: Full=Neuropeptide-like 1 {ECO:0000312|EMBL:EFN73979.1};
DE Contains:
DE RecName: Full=Neuropeptide-like 1-1 {ECO:0000303|PubMed:25641051};
DE Contains:
DE RecName: Full=Neuropeptide-like 1-2 {ECO:0000303|PubMed:25641051};
DE Contains:
DE RecName: Full=Neuropeptide-like 1-3 {ECO:0000303|PubMed:25641051};
DE Contains:
DE RecName: Full=Neuropeptide-like 1-4 {ECO:0000303|PubMed:25641051};
DE Contains:
DE RecName: Full=Neuropeptide-like 1-5 {ECO:0000303|PubMed:25641051};
DE Contains:
DE RecName: Full=Neuropeptide-like 1-6 {ECO:0000303|PubMed:25641051};
DE Contains:
DE RecName: Full=Neuropeptide-like 1-7 {ECO:0000303|PubMed:25641051};
GN ORFNames=EAG_05659 {ECO:0000312|EMBL:EFN73979.1};
OS Camponotus floridanus (Florida carpenter ant).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Hymenoptera; Apocrita; Aculeata; Formicoidea;
OC Formicidae; Formicinae; Camponotus.
OX NCBI_TaxID=104421;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=20798317; DOI=10.1126/science.1192428;
RA Bonasio R., Zhang G., Ye C., Mutti N.S., Fang X., Qin N., Donahue G.,
RA Yang P., Li Q., Li C., Zhang P., Huang Z., Berger S.L., Reinberg D.,
RA Wang J., Liebig J.;
RT "Genomic comparison of the ants Camponotus floridanus and Harpegnathos
RT saltator.";
RL Science 329:1068-1071(2010).
RN [2] {ECO:0000305}
RP PROTEIN SEQUENCE OF 182-194; 198-210; 214-227; 231-244; 248-260; 264-281
RP AND 302-318, TISSUE SPECIFICITY, MASS SPECTROMETRY, IDENTIFICATION BY MASS
RP SPECTROMETRY, AND AMIDATION AT THR-194; SER-210; SER-227; SER-244; TYR-260;
RP GLU-281 AND TYR-318.
RX PubMed=25641051; DOI=10.1021/pr5011636;
RA Schmitt F., Vanselow J.T., Schlosser A., Kahnt J., Roessler W., Wegener C.;
RT "Neuropeptidomics of the carpenter ant Camponotus floridanus.";
RL J. Proteome Res. 14:1504-1514(2015).
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000305|PubMed:25641051}.
CC -!- MASS SPECTROMETRY: [Neuropeptide-like 1-1]: Mass=1359.73;
CC Method=Electrospray; Note=Neuropeptide-like 1-1.;
CC Evidence={ECO:0000269|PubMed:25641051};
CC -!- MASS SPECTROMETRY: [Neuropeptide-like 1-2]: Mass=1358.72;
CC Method=Electrospray; Note=Neuropeptide-like 1-2.;
CC Evidence={ECO:0000269|PubMed:25641051};
CC -!- MASS SPECTROMETRY: [Neuropeptide-like 1-3]: Mass=1471.8;
CC Method=Electrospray; Note=Neuropeptide-like 1-3.;
CC Evidence={ECO:0000269|PubMed:25641051};
CC -!- MASS SPECTROMETRY: [Neuropeptide-like 1-4]: Mass=1611.83;
CC Method=Electrospray; Note=Neuropeptide-like 1-4.;
CC Evidence={ECO:0000269|PubMed:25641051};
CC -!- MASS SPECTROMETRY: [Neuropeptide-like 1-5]: Mass=1375.73;
CC Method=Electrospray; Note=Neuropeptide-like 1-5.;
CC Evidence={ECO:0000269|PubMed:25641051};
CC -!- MASS SPECTROMETRY: [Neuropeptide-like 1-6]: Mass=2048.96;
CC Method=Electrospray; Note=Neuropeptide-like 1-6.;
CC Evidence={ECO:0000269|PubMed:25641051};
CC -!- MASS SPECTROMETRY: [Neuropeptide-like 1-7]: Mass=2036.12;
CC Method=Electrospray; Note=Neuropeptide-like 1-7.;
CC Evidence={ECO:0000269|PubMed:25641051};
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DR EMBL; GL435132; EFN73979.1; -; Genomic_DNA.
DR AlphaFoldDB; E1ZXU8; -.
DR STRING; 104421.E1ZXU8; -.
DR InParanoid; E1ZXU8; -.
DR OMA; DCRHGFK; -.
DR Proteomes; UP000000311; Unassembled WGS sequence.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR GO; GO:0007218; P:neuropeptide signaling pathway; IEA:UniProtKB-KW.
PE 1: Evidence at protein level;
KW Amidation; Cleavage on pair of basic residues; Direct protein sequencing;
KW Neuropeptide; Reference proteome; Secreted.
FT PROPEP 1..179
FT /evidence="ECO:0000305|PubMed:25641051"
FT /id="PRO_0000434224"
FT PEPTIDE 182..194
FT /note="Neuropeptide-like 1-1"
FT /evidence="ECO:0000269|PubMed:25641051"
FT /id="PRO_0000434225"
FT PEPTIDE 198..210
FT /note="Neuropeptide-like 1-2"
FT /evidence="ECO:0000269|PubMed:25641051"
FT /id="PRO_0000434226"
FT PEPTIDE 214..227
FT /note="Neuropeptide-like 1-3"
FT /evidence="ECO:0000269|PubMed:25641051"
FT /id="PRO_0000434227"
FT PEPTIDE 231..244
FT /note="Neuropeptide-like 1-4"
FT /evidence="ECO:0000269|PubMed:25641051"
FT /id="PRO_0000434228"
FT PEPTIDE 248..260
FT /note="Neuropeptide-like 1-5"
FT /evidence="ECO:0000269|PubMed:25641051"
FT /id="PRO_0000434229"
FT PEPTIDE 264..281
FT /note="Neuropeptide-like 1-6"
FT /evidence="ECO:0000269|PubMed:25641051"
FT /id="PRO_0000434230"
FT PROPEP 285..299
FT /evidence="ECO:0000305|PubMed:25641051"
FT /id="PRO_0000434231"
FT PEPTIDE 302..318
FT /note="Neuropeptide-like 1-7"
FT /evidence="ECO:0000269|PubMed:25641051"
FT /id="PRO_0000434232"
FT PROPEP 321..588
FT /evidence="ECO:0000305|PubMed:25641051"
FT /id="PRO_0000434233"
FT REGION 115..143
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 342..382
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 121..138
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 342..356
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 361..382
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT MOD_RES 194
FT /note="Threonine amide"
FT /evidence="ECO:0000269|PubMed:25641051"
FT MOD_RES 210
FT /note="Serine amide"
FT /evidence="ECO:0000269|PubMed:25641051"
FT MOD_RES 227
FT /note="Serine amide"
FT /evidence="ECO:0000269|PubMed:25641051"
FT MOD_RES 244
FT /note="Serine amide"
FT /evidence="ECO:0000269|PubMed:25641051"
FT MOD_RES 260
FT /note="Tyrosine amide"
FT /evidence="ECO:0000269|PubMed:25641051"
FT MOD_RES 281
FT /note="Glutamic acid 1-amide"
FT /evidence="ECO:0000269|PubMed:25641051"
FT MOD_RES 318
FT /note="Tyrosine amide"
FT /evidence="ECO:0000269|PubMed:25641051"
SQ SEQUENCE 588 AA; 67266 MW; 09B3CA27314767C8 CRC64;
MQCIPKKTFM AMLRIPEVRS NLAAYLRTAL MVQEVKNHDD MVHLKALSSE ENEDFEICIP
GGTYLELFRN PVLRSHLSAM ERSYKFPGRF LSEEVDSRDL IPESEKRSLA TLAKNGDLPI
TIQERESDND DEEKRSASSS DNVGSLHELF DEVSYRRRTP EIYDYLTEQD PEVLEYSPDK
RNVGSLARDF ALPTGRRHIA SVARDHGLPS GKRNVGSLAR QSMLPLSGKR NVASLARYYM
LPQSGKRNVA ALARDSSLPY GKRYLGSLAR SGSYPTRDYD EGKRSIASLA RSGDWPSVAK
RGRMTSGRIM ARVLNRRYGR SLSDDREAPS EPLDLQQLIR QGNSEGKENE WQATPFTVSE
DLDEGKAKNR SNRRIEASQT RHKRQIDFSD EYPLPVMQNN MLDYEDMMEA IADHYPNAEK
RFMGQTVSQP PLRVFRRVLF SYLDVMSTVF CRTCNQVEPH LLQTEKIYHI YVCQYQQIYQ
PHHVKDNPNT NEPTTMYNHY VQKKCSPMSS SSTHGIITVV RENPADGSSS NYTPDASTRS
LRPIFTPKTR YLQSLHGDCR HGFKRFLLLP DIDNFLRTSN SHIAPRSM
