ID   NPMA_BOVIN              Reviewed;          18 AA.
AC   P15506;
DT   01-APR-1990, integrated into UniProtKB/Swiss-Prot.
DT   01-APR-1990, sequence version 1.
DT   25-MAY-2022, entry version 51.
DE   RecName: Full=Morphine-modulating neuropeptide A;
OS   Bos taurus (Bovine).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC   Bovinae; Bos.
OX   NCBI_TaxID=9913;
RN   [1]
RP   PROTEIN SEQUENCE, AMIDATION AT PHE-18, AND SYNTHESIS.
RC   TISSUE=Brain;
RX   PubMed=3865193; DOI=10.1073/pnas.82.22.7757;
RA   Yang H.-Y.T., Fratta W., Majane E.A., Costa E.;
RT   "Isolation, sequencing, synthesis, and pharmacological characterization of
RT   two brain neuropeptides that modulate the action of morphine.";
RL   Proc. Natl. Acad. Sci. U.S.A. 82:7757-7761(1985).
CC   -!- FUNCTION: Modulates the action of morphine.
CC   -!- SUBCELLULAR LOCATION: Secreted.
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DR   PIR; A24749; A24749.
DR   AlphaFoldDB; P15506; -.
DR   Proteomes; UP000009136; Unplaced.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0007218; P:neuropeptide signaling pathway; IEA:UniProtKB-KW.
PE   1: Evidence at protein level;
KW   Amidation; Direct protein sequencing; Neuropeptide; Reference proteome;
KW   Secreted.
FT   PEPTIDE         1..18
FT                   /note="Morphine-modulating neuropeptide A"
FT                   /id="PRO_0000044177"
FT   MOD_RES         18
FT                   /note="Phenylalanine amide"
FT                   /evidence="ECO:0000269|PubMed:3865193"
SQ   SEQUENCE   18 AA;  1921 MW;  EC52DAE1F45CFCFB CRC64;
     AGEGLSSPFW SLAAPQRF