ID   NPR3_ASPOR              Reviewed;         731 AA.
AC   Q2UBT9;
DT   11-SEP-2007, integrated into UniProtKB/Swiss-Prot.
DT   24-JAN-2006, sequence version 1.
DT   25-MAY-2022, entry version 69.
DE   RecName: Full=Nitrogen permease regulator 3;
DE   AltName: Full=Required for meiotic nuclear division protein 11;
DE   Flags: Precursor;
GN   Name=npr3; Synonyms=rmd11; ORFNames=AO090012000867;
OS   Aspergillus oryzae (strain ATCC 42149 / RIB 40) (Yellow koji mold).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus;
OC   Aspergillus subgen. Circumdati.
OX   NCBI_TaxID=510516;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 42149 / RIB 40;
RX   PubMed=16372010; DOI=10.1038/nature04300;
RA   Machida M., Asai K., Sano M., Tanaka T., Kumagai T., Terai G., Kusumoto K.,
RA   Arima T., Akita O., Kashiwagi Y., Abe K., Gomi K., Horiuchi H.,
RA   Kitamoto K., Kobayashi T., Takeuchi M., Denning D.W., Galagan J.E.,
RA   Nierman W.C., Yu J., Archer D.B., Bennett J.W., Bhatnagar D.,
RA   Cleveland T.E., Fedorova N.D., Gotoh O., Horikawa H., Hosoyama A.,
RA   Ichinomiya M., Igarashi R., Iwashita K., Juvvadi P.R., Kato M., Kato Y.,
RA   Kin T., Kokubun A., Maeda H., Maeyama N., Maruyama J., Nagasaki H.,
RA   Nakajima T., Oda K., Okada K., Paulsen I., Sakamoto K., Sawano T.,
RA   Takahashi M., Takase K., Terabayashi Y., Wortman J.R., Yamada O.,
RA   Yamagata Y., Anazawa H., Hata Y., Koide Y., Komori T., Koyama Y.,
RA   Minetoki T., Suharnan S., Tanaka A., Isono K., Kuhara S., Ogasawara N.,
RA   Kikuchi H.;
RT   "Genome sequencing and analysis of Aspergillus oryzae.";
RL   Nature 438:1157-1161(2005).
CC   -!- FUNCTION: Mediates inactivation of the TORC1 complex in response to
CC       amino acid starvation. Required for meiotic nuclear division (By
CC       similarity). {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the NPR3 family. {ECO:0000305}.
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DR   EMBL; AP007161; BAE60976.1; -; Genomic_DNA.
DR   AlphaFoldDB; Q2UBT9; -.
DR   STRING; 510516.Q2UBT9; -.
DR   EnsemblFungi; BAE60976; BAE60976; AO090012000867.
DR   HOGENOM; CLU_014314_1_0_1; -.
DR   OMA; ARTDYVW; -.
DR   Proteomes; UP000006564; Chromosome 4.
DR   GO; GO:0051321; P:meiotic cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0032007; P:negative regulation of TOR signaling; IEA:InterPro.
DR   InterPro; IPR005365; Npr3.
DR   PANTHER; PTHR13153; PTHR13153; 1.
DR   Pfam; PF03666; NPR3; 1.
PE   3: Inferred from homology;
KW   Meiosis; Reference proteome; Signal.
FT   SIGNAL          1..23
FT                   /evidence="ECO:0000255"
FT   CHAIN           24..731
FT                   /note="Nitrogen permease regulator 3"
FT                   /id="PRO_0000301794"
FT   REGION          34..90
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          129..156
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          168..187
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          549..599
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        138..156
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        570..585
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   731 AA;  81452 MW;  85275344D9AF1B6E CRC64;
     MSSIARPPDP CLVAIILIVR SRAGPRFVFH YPPNPLSENG LRAAPKGRRP SRAKSAKSND
     SSSSEESGST SDEDEEEAHA QSQNASSADV WEKLLSPSRS WHKRRFEVGI NDLAFVGWPV
     FVREDGTWRK QRRKKKKTKP EWEGGELGHN EIPGDVRDDA DEAIAASTET LSPHTMTASE
     SQRASMGSIR SSRTLSEMLD GDDKDSMTMF NVVFVLDPPL LEYSMRIREI YDNIIKKFAK
     ALKWEQARTD YVWREAQHIS HIKEKAKETR TSVNTLYSEL INHSSLARAI YTVYSNISAS
     KIASVSLSPD VSISLQIPPL TSTPYLPGPG DKAYPGLWLT TADSVTPADD PTADENTAPH
     QVLAKHFALL LLSDEATILK DVEASGGALA PALAHYIRCS KPTKSFAQIS ALSGIPLSTI
     QMLASHLVYW RRARAIPPLH QRDVYFVSPN CDLSKLEVAT AAYQLAFPTL PSLPKMLSAL
     SGTPRPYGSF IPSKDHKEAY FAILAWLLRG GWVTQLRTFA RVKVSPEIKM AVERALRREE
     VDKYLSKQGS SILSDHSKHN GDTSKNDDDD ASSSSSSSLA SQDSGEETPM PGRYKPDSKL
     HLSHSLLDQD TSLKTASLIL FPHRAPPLES RWLDEIVSRF PKQPRFSVRG RANIDENDPE
     YAGLRTAMKD LWPVYIKYFN GMDALEKVPV RENLKRKLVW QVLTRLGLVT GSQSYIELDP
     SEQVLIGVRH W