ID   NPR3_ASPTN              Reviewed;         818 AA.
AC   Q0CQ46;
DT   11-SEP-2007, integrated into UniProtKB/Swiss-Prot.
DT   17-OCT-2006, sequence version 1.
DT   25-MAY-2022, entry version 57.
DE   RecName: Full=Nitrogen permease regulator 3;
DE   AltName: Full=Required for meiotic nuclear division protein 11;
DE   Flags: Precursor;
GN   Name=npr3; Synonyms=rmd11; ORFNames=ATEG_04188;
OS   Aspergillus terreus (strain NIH 2624 / FGSC A1156).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus;
OC   Aspergillus subgen. Circumdati.
OX   NCBI_TaxID=341663;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NIH 2624 / FGSC A1156;
RA   Birren B.W., Lander E.S., Galagan J.E., Nusbaum C., Devon K., Henn M.,
RA   Ma L.-J., Jaffe D.B., Butler J., Alvarez P., Gnerre S., Grabherr M.,
RA   Kleber M., Mauceli E.W., Brockman W., Rounsley S., Young S.K., LaButti K.,
RA   Pushparaj V., DeCaprio D., Crawford M., Koehrsen M., Engels R.,
RA   Montgomery P., Pearson M., Howarth C., Larson L., Luoma S., White J.,
RA   Alvarado L., Kodira C.D., Zeng Q., Oleary S., Yandava C., Denning D.W.,
RA   Nierman W.C., Milne T., Madden K.;
RT   "Annotation of the Aspergillus terreus NIH2624 genome.";
RL   Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Mediates inactivation of the TORC1 complex in response to
CC       amino acid starvation. Required for meiotic nuclear division (By
CC       similarity). {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the NPR3 family. {ECO:0000305}.
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DR   EMBL; CH476598; EAU35990.1; -; Genomic_DNA.
DR   RefSeq; XP_001213366.1; XM_001213366.1.
DR   AlphaFoldDB; Q0CQ46; -.
DR   SMR; Q0CQ46; -.
DR   STRING; 341663.Q0CQ46; -.
DR   PRIDE; Q0CQ46; -.
DR   EnsemblFungi; EAU35990; EAU35990; ATEG_04188.
DR   GeneID; 4318563; -.
DR   VEuPathDB; FungiDB:ATEG_04188; -.
DR   eggNOG; KOG3830; Eukaryota.
DR   HOGENOM; CLU_014314_1_0_1; -.
DR   OMA; ARTDYVW; -.
DR   OrthoDB; 628619at2759; -.
DR   Proteomes; UP000007963; Unassembled WGS sequence.
DR   GO; GO:0051321; P:meiotic cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0032007; P:negative regulation of TOR signaling; IEA:InterPro.
DR   InterPro; IPR005365; Npr3.
DR   PANTHER; PTHR13153; PTHR13153; 1.
DR   Pfam; PF03666; NPR3; 1.
PE   3: Inferred from homology;
KW   Meiosis; Reference proteome; Signal.
FT   SIGNAL          1..23
FT                   /evidence="ECO:0000255"
FT   CHAIN           24..818
FT                   /note="Nitrogen permease regulator 3"
FT                   /id="PRO_0000301795"
FT   REGION          31..97
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          118..188
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          219..293
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          640..685
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        82..97
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        151..166
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        230..254
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        261..288
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   818 AA;  89700 MW;  4E4910E95471959E CRC64;
     MSSIARPPDP CLVAIILIVR SRAGPRFVFH YPPNPLSDNG LKSAKKARRA SRTKSTRSSD
     SSSSDDSGPT SDEDEEEHQR LQQQQQQQQA QQQSSHIAGQ PLSVTHLAGS AVSRRSSNFG
     LDDHVGMAAS PGGESARAGS IGSGRTLLRK RGGNSDVEDD AGTSSDRQDD AGSSAMGGGR
     KGGPPPWESL LGLPAKVWEK LLSPSRAWHK RRFEVGINDL GRKKKKKPRA ERQGGELGHN
     EHTDDAREEA DAGEELMVAS TETLSPHQMS ASESQRASIA SSKTGRAPSE SLDVDDKDRM
     TMFNVVFVLD PPLLEYSMRS REIYDNIIKK FAKALKWEQA RTGYVWREAQ HISHIKEKAK
     EKGTSVNALY TELINQSSLA RAIYTVYTSI AASKIASVSL SPDVSISLQI PPLTSTPYLP
     GPTDEAYPGL WLTTADSVTP VDDPTANEST APHQVLAKHF ALLLLDSEAT ILKDVEASGG
     ALAPALAHYI RCSKPTKSFA QISASSGIPL PTIQMLASHL VYWRRARAIP PLHQRDTYIV
     SPNCDLSKLD VATAAYQLAF PTLPSLPKML SALSGTPRPY GSFIPSKDHK DAYFAILAWL
     LRGGWVTQLR SFSRVKVTPE IKMAVEVALR REEVDKYLSK RGNVSSDAGN RGDSSEHDDD
     DASSSSSSSL ASQDSGEETP MPGRYKQDSE LQLTRSLLDR NTSLKTSSLI LFPHRASPLE
     SRWMDEIVSR FPDNPRPARP GTEGDPEQAG LQTSLKQFWP TYIKYFNGYD ALEKISVREN
     LKRKHVWQVL TRLGLVTGSQ ASLDLDPREQ VLVSVRHW