NPS11_ARATH
ID NPS11_ARATH Reviewed; 265 AA.
AC Q944A9; O82173;
DT 17-JAN-2003, integrated into UniProtKB/Swiss-Prot.
DT 03-MAY-2011, sequence version 2.
DT 03-AUG-2022, entry version 130.
DE RecName: Full=Novel plant SNARE 11;
DE Short=AtNPSN11;
GN Name=NPSN11; OrderedLocusNames=At2g35190; ORFNames=T4C15.14;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10617197; DOI=10.1038/45471;
RA Lin X., Kaul S., Rounsley S.D., Shea T.P., Benito M.-I., Town C.D.,
RA Fujii C.Y., Mason T.M., Bowman C.L., Barnstead M.E., Feldblyum T.V.,
RA Buell C.R., Ketchum K.A., Lee J.J., Ronning C.M., Koo H.L., Moffat K.S.,
RA Cronin L.A., Shen M., Pai G., Van Aken S., Umayam L., Tallon L.J.,
RA Gill J.E., Adams M.D., Carrera A.J., Creasy T.H., Goodman H.M.,
RA Somerville C.R., Copenhaver G.P., Preuss D., Nierman W.C., White O.,
RA Eisen J.A., Salzberg S.L., Fraser C.M., Venter J.C.;
RT "Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana.";
RL Nature 402:761-768(1999).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=14593172; DOI=10.1126/science.1088305;
RA Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA Ecker J.R.;
RT "Empirical analysis of transcriptional activity in the Arabidopsis
RT genome.";
RL Science 302:842-846(2003).
RN [4]
RP CHARACTERIZATION.
RX PubMed=12068098; DOI=10.1104/pp.003970;
RA Zheng H., Bednarek S.Y., Sanderfoot A.A., Alonso J., Ecker J.R.,
RA Raikhel N.V.;
RT "NPSN11 is a cell plate-associated SNARE protein that interacts with the
RT syntaxin KNOLLE.";
RL Plant Physiol. 129:530-539(2002).
CC -!- FUNCTION: t-SNARE involved in diverse vesicle trafficking and membrane
CC fusion processes, including cell plate formation.
CC -!- SUBUNIT: Interacts with KNOLLE to form a t-SNARE complex. Does not
CC interact with SYP21, VTI12 or VPS45.
CC -!- SUBCELLULAR LOCATION: Membrane; Single-pass type IV membrane protein.
CC Note=Cell plate during cell division.
CC -!- TISSUE SPECIFICITY: Expressed in roots, stems, flower, siliques,
CC expanding leaves, but not in mature leaves. Not limited to dividing
CC cells.
CC -!- SIMILARITY: Belongs to the novel plant SNARE family. {ECO:0000305}.
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DR EMBL; AC004667; AAC61818.2; -; Genomic_DNA.
DR EMBL; CP002685; AEC09077.1; -; Genomic_DNA.
DR EMBL; AF439822; AAL27494.1; -; mRNA.
DR EMBL; AY143839; AAN28778.1; -; mRNA.
DR PIR; F84765; F84765.
DR RefSeq; NP_565800.1; NM_129072.4.
DR AlphaFoldDB; Q944A9; -.
DR SMR; Q944A9; -.
DR BioGRID; 3432; 12.
DR IntAct; Q944A9; 6.
DR STRING; 3702.AT2G35190.1; -.
DR SwissPalm; Q944A9; -.
DR PaxDb; Q944A9; -.
DR PRIDE; Q944A9; -.
DR ProteomicsDB; 250516; -.
DR EnsemblPlants; AT2G35190.1; AT2G35190.1; AT2G35190.
DR GeneID; 818086; -.
DR Gramene; AT2G35190.1; AT2G35190.1; AT2G35190.
DR KEGG; ath:AT2G35190; -.
DR Araport; AT2G35190; -.
DR TAIR; locus:2063459; AT2G35190.
DR eggNOG; ENOG502S126; Eukaryota.
DR HOGENOM; CLU_058321_0_0_1; -.
DR InParanoid; Q944A9; -.
DR OMA; MMVNESE; -.
DR OrthoDB; 1198270at2759; -.
DR PRO; PR:Q944A9; -.
DR Proteomes; UP000006548; Chromosome 2.
DR ExpressionAtlas; Q944A9; baseline and differential.
DR Genevisible; Q944A9; AT.
DR GO; GO:0009504; C:cell plate; IDA:TAIR.
DR GO; GO:0005783; C:endoplasmic reticulum; HDA:TAIR.
DR GO; GO:0005789; C:endoplasmic reticulum membrane; IBA:GO_Central.
DR GO; GO:0012507; C:ER to Golgi transport vesicle membrane; IBA:GO_Central.
DR GO; GO:0005794; C:Golgi apparatus; IBA:GO_Central.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0031902; C:late endosome membrane; IBA:GO_Central.
DR GO; GO:0031201; C:SNARE complex; IBA:GO_Central.
DR GO; GO:0005484; F:SNAP receptor activity; ISS:TAIR.
DR GO; GO:0000149; F:SNARE binding; IBA:GO_Central.
DR GO; GO:0000911; P:cytokinesis by cell plate formation; TAS:TAIR.
DR GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR GO; GO:0006890; P:retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum; IEA:InterPro.
DR GO; GO:0006906; P:vesicle fusion; IBA:GO_Central.
DR CDD; cd15861; SNARE_SNAP25N_23N_29N_SEC9N; 1.
DR InterPro; IPR044766; NPSN/SNAP25-like_N_SNARE.
DR InterPro; IPR005606; Sec20.
DR InterPro; IPR000727; T_SNARE_dom.
DR Pfam; PF03908; Sec20; 1.
DR SMART; SM00397; t_SNARE; 1.
DR PROSITE; PS50192; T_SNARE; 1.
PE 1: Evidence at protein level;
KW Cell cycle; Cell division; Coiled coil; Membrane; Protein transport;
KW Reference proteome; Transmembrane; Transmembrane helix; Transport.
FT CHAIN 1..265
FT /note="Novel plant SNARE 11"
FT /id="PRO_0000213616"
FT TOPO_DOM 1..215
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 216..236
FT /note="Helical; Anchor for type IV membrane protein"
FT /evidence="ECO:0000255"
FT TOPO_DOM 237..265
FT /note="Vesicular"
FT /evidence="ECO:0000255"
FT DOMAIN 144..206
FT /note="t-SNARE coiled-coil homology"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00202"
FT COILED 30..75
FT /evidence="ECO:0000255"
FT CONFLICT 177
FT /note="A -> P (in Ref. 3; AAL27494/AAN28778)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 265 AA; 29872 MW; 1232FE8448215128 CRC64;
MDPISAVSEE LAEIEGQIND IFRALSNGFQ KLEKIKDANR QSRQLEELTD KMRDCKSLIK
DFDREIKSLE SGNDASTNRM LNDRRQSMVK ELNSYVALKK KYSSNLASNN KRVDLFDGPG
EEHMEENVLL ASNMSNQELM DKGNSMMDDT DQAIERGKKI VQETINVGTD TSAALKAQTE
QMSRVVNELD SIHFSLKKAS KLVKEIGRQV ATDKCIMAFL FLIVIGVIAI IIVKIVNPNN
KDIRDIPGVG LAPPAMNRRL LWNHY
