NPY1R_SHEEP
ID NPY1R_SHEEP Reviewed; 116 AA.
AC Q28602;
DT 15-JUL-1998, integrated into UniProtKB/Swiss-Prot.
DT 01-NOV-1996, sequence version 1.
DT 25-MAY-2022, entry version 83.
DE RecName: Full=Neuropeptide Y receptor type 1;
DE Short=NPY1-R;
DE Flags: Fragment;
GN Name=NPY1R;
OS Ovis aries (Sheep).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC Caprinae; Ovis.
OX NCBI_TaxID=9940;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA].
RC TISSUE=Hypothalamus;
RX PubMed=9347250; DOI=10.1016/s0739-7240(97)00028-3;
RA Dyer C.J., Simmons J.M., Matteri R.L., Keisler D.H.;
RT "cDNA cloning and tissue-specific gene expression of ovine leptin, NPY-Y1
RT receptor, and NPY-Y2 receptor.";
RL Domest. Anim. Endocrinol. 14:295-303(1997).
CC -!- FUNCTION: Receptor for neuropeptide Y and peptide YY.
CC -!- SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein.
CC -!- SIMILARITY: Belongs to the G-protein coupled receptor 1 family.
CC {ECO:0000255|PROSITE-ProRule:PRU00521}.
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DR EMBL; U62122; AAB51032.1; -; mRNA.
DR AlphaFoldDB; Q28602; -.
DR SMR; Q28602; -.
DR STRING; 9940.ENSOARP00000014658; -.
DR eggNOG; KOG3656; Eukaryota.
DR Proteomes; UP000002356; Unplaced.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0004983; F:neuropeptide Y receptor activity; IEA:InterPro.
DR InterPro; IPR000276; GPCR_Rhodpsn.
DR InterPro; IPR017452; GPCR_Rhodpsn_7TM.
DR InterPro; IPR000351; NPY1_rcpt.
DR PANTHER; PTHR24235:SF24; PTHR24235:SF24; 1.
DR Pfam; PF00001; 7tm_1; 1.
DR PRINTS; PR00237; GPCRRHODOPSN.
DR PROSITE; PS50262; G_PROTEIN_RECEP_F1_2; 1.
PE 2: Evidence at transcript level;
KW Cell membrane; G-protein coupled receptor; Glycoprotein; Lipoprotein;
KW Membrane; Palmitate; Receptor; Reference proteome; Transducer;
KW Transmembrane; Transmembrane helix.
FT CHAIN <1..>116
FT /note="Neuropeptide Y receptor type 1"
FT /id="PRO_0000069924"
FT TRANSMEM <1..6
FT /note="Helical; Name=3"
FT /evidence="ECO:0000255"
FT TOPO_DOM 7..24
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 25..45
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 46..81
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 82..102
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 103..>116
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT CARBOHYD 56
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT NON_TER 1
FT NON_TER 116
SQ SEQUENCE 116 AA; 13690 MW; 4E398366FFAC6670 CRC64;
LVLIAVERHQ LIINPRGWRP SNRHAYVGIA VIWVLAVASS LPFLIYQVLT DEPFQNVTLD
AFKDKYVCFD KFPSDSHRLS YTTLLLVLQY FGPLCFIFIC YFKIYIRLKR RNNMMD