ID   NPY2R_SHEEP             Reviewed;         146 AA.
AC   P79211;
DT   15-JUL-1998, integrated into UniProtKB/Swiss-Prot.
DT   01-MAY-1997, sequence version 1.
DT   25-MAY-2022, entry version 82.
DE   RecName: Full=Neuropeptide Y receptor type 2;
DE            Short=NPY2-R;
DE   AltName: Full=NPY-Y2 receptor;
DE            Short=Y2 receptor;
DE   Flags: Fragment;
GN   Name=NPY2R;
OS   Ovis aries (Sheep).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC   Caprinae; Ovis.
OX   NCBI_TaxID=9940;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RC   TISSUE=Hypothalamus;
RX   PubMed=9347250; DOI=10.1016/s0739-7240(97)00028-3;
RA   Dyer C.J., Simmons J.M., Matteri R.L., Keisler D.H.;
RT   "cDNA cloning and tissue-specific gene expression of ovine leptin, NPY-Y1
RT   receptor, and NPY-Y2 receptor.";
RL   Domest. Anim. Endocrinol. 14:295-303(1997).
CC   -!- FUNCTION: Receptor for neuropeptide Y and peptide YY.
CC   -!- SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein.
CC   -!- SIMILARITY: Belongs to the G-protein coupled receptor 1 family.
CC       {ECO:0000255|PROSITE-ProRule:PRU00521}.
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DR   EMBL; U83458; AAB41232.1; -; mRNA.
DR   AlphaFoldDB; P79211; -.
DR   SMR; P79211; -.
DR   STRING; 9940.ENSOARP00000016097; -.
DR   eggNOG; KOG3656; Eukaryota.
DR   Proteomes; UP000002356; Unplaced.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0004983; F:neuropeptide Y receptor activity; IEA:InterPro.
DR   InterPro; IPR000276; GPCR_Rhodpsn.
DR   InterPro; IPR017452; GPCR_Rhodpsn_7TM.
DR   InterPro; IPR001358; NPY2_rcpt.
DR   Pfam; PF00001; 7tm_1; 1.
DR   PRINTS; PR00237; GPCRRHODOPSN.
DR   PRINTS; PR01014; NRPEPTIDEY2R.
DR   PROSITE; PS00237; G_PROTEIN_RECEP_F1_1; 1.
DR   PROSITE; PS50262; G_PROTEIN_RECEP_F1_2; 1.
PE   2: Evidence at transcript level;
KW   Cell membrane; Disulfide bond; G-protein coupled receptor; Lipoprotein;
KW   Membrane; Palmitate; Receptor; Reference proteome; Transducer;
KW   Transmembrane; Transmembrane helix.
FT   CHAIN           <1..>146
FT                   /note="Neuropeptide Y receptor type 2"
FT                   /id="PRO_0000069933"
FT   TOPO_DOM        <1..8
FT                   /note="Extracellular"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        9..29
FT                   /note="Helical; Name=3"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        30..49
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        50..70
FT                   /note="Helical; Name=4"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        71..100
FT                   /note="Extracellular"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        101..121
FT                   /note="Helical; Name=5"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        122..>146
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   DISULFID        7..87
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00521"
FT   NON_TER         1
FT   NON_TER         146
SQ   SEQUENCE   146 AA;  16315 MW;  B34D9F082ADB2900 CRC64;
     KMGPVLCHLV PYAQGLAVQV STITLTVIAL DRHRCIVYHL ESKISKQISF LIIGLAWGVS
     ALLASPLAIF REYSLIEIIP DFEIVACTEK WPGEEKGIYG TVYSLLSLLI LYVLPLGIIS
     FSYARIWSKL KNHVSPGAAH DHYHQR